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Items: 1 to 20 of 109

1.

5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia.

Ley TJ, DeSimone J, Anagnou NP, Keller GH, Humphries RK, Turner PH, Young NS, Keller P, Nienhuis AW.

N Engl J Med. 1982 Dec 9;307(24):1469-75.

PMID:
6183586
2.

5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia.

Ley TJ, DeSimone J, Noguchi CT, Turner PH, Schechter AN, Heller P, Nienhuis AW.

Blood. 1983 Aug;62(2):370-80.

3.

DNA methylation and globin gene expression in patients treated with 5-azacytidine.

Ley TJ, Anagnou NP, Noguchi CT, Schechter AN, DeSimone J, Heller P, Nienhuis AW.

Prog Clin Biol Res. 1983;134:457-74.

PMID:
6198660
4.

5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin.

Humphries RK, Dover G, Young NS, Moore JG, Charache S, Ley T, Nienhuis AW.

J Clin Invest. 1985 Feb;75(2):547-57.

5.

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders.

Perrine SP, Ginder GD, Faller DV, Dover GH, Ikuta T, Witkowska HE, Cai SP, Vichinsky EP, Olivieri NF.

N Engl J Med. 1993 Jan 14;328(2):81-6.

6.

In vivo demethylation of chicken embryonic beta-type globin genes with 5-azacytidine.

Ginder GD, Whitters M, Kelley K, Chase RA.

Prog Clin Biol Res. 1983;134:501-10.

PMID:
6198663
7.
9.

Induction of hemoglobin F synthesis in patients with beta thalassemia.

Ley TJ, Nienhuis AW.

Annu Rev Med. 1985;36:485-98. Review.

PMID:
2581500
10.

Human leukemia K-562 cells: induction of erythroid differentiation by 5-azacytidine.

Gambari R, del Senno L, Barbieri R, Viola L, Tripodi M, Raschellà G, Fantoni A.

Cell Differ. 1984 Jun;14(2):87-97.

PMID:
6205767
11.

Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.

Smith RD, Li J, Noguchi CT, Schechter AN.

Blood. 2000 Feb 1;95(3):863-9.

12.
13.

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.

DeSimone J, Heller P, Hall L, Zwiers D.

Proc Natl Acad Sci U S A. 1982 Jul;79(14):4428-31.

14.

Perturbations in the erythroid marrow progenitor cell pools may play a role in the augmentation of HbF by 5-azacytidine.

Torrealba-de Ron AT, Papayannopoulou T, Knapp MS, Fu MF, Knitter G, Stamatoyannopoulos G.

Blood. 1984 Jan;63(1):201-10.

15.

Cellular and molecular effects of a pulse butyrate regimen and new inducers of globin gene expression and hematopoiesis.

Ikuta T, Atweh G, Boosalis V, White GL, Da Fonseca S, Boosalis M, Faller DV, Perrine SP.

Ann N Y Acad Sci. 1998 Jun 30;850:87-99. Review.

PMID:
9668531
16.

Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease.

Fucharoen S, Siritanaratkul N, Winichagoon P, Chowthaworn J, Siriboon W, Muangsup W, Chaicharoen S, Poolsup N, Chindavijak B, Pootrakul P, Piankijagum A, Schechter AN, Rodgers GP.

Blood. 1996 Feb 1;87(3):887-92.

17.

DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11.

Ley TJ, Chiang YL, Haidaris D, Anagnou NP, Wilson VL, Anderson WF.

Proc Natl Acad Sci U S A. 1984 Nov;81(21):6618-22.

18.

Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy.

Persons DA, Allay ER, Sabatino DE, Kelly P, Bodine DM, Nienhuis AW.

Blood. 2001 May 15;97(10):3275-82.

19.
20.

5-Azacytidine increases fetal hemoglobin production in a patient with sickle cell disease.

Dover GJ, Charache SH, Boyer SH, Talbot CC Jr, Smith KD.

Prog Clin Biol Res. 1983;134:475-88.

PMID:
6198661
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