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Results: 1 to 20 of 81

2.

A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group.

Bone RC, Balk RA, Fein AM, Perl TM, Wenzel RP, Reines HD, Quenzer RW, Iberti TJ, Macintyre N, Schein RM.

Crit Care Med. 1995 Jun;23(6):994-1006. Erratum in: Crit Care Med 1995 Sep;23(9):1616.

PMID:
7774238
[PubMed - indexed for MEDLINE]
3.

Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group.

Dhainaut JF, Tenaillon A, Le Tulzo Y, Schlemmer B, Solet JP, Wolff M, Holzapfel L, Zeni F, Dreyfuss D, Mira JP, et al.

Crit Care Med. 1994 Nov;22(11):1720-8.

PMID:
7956274
[PubMed - indexed for MEDLINE]
4.

Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group.

Ziegler EJ, Fisher CJ Jr, Sprung CL, Straube RC, Sadoff JC, Foulke GE, Wortel CH, Fink MP, Dellinger RP, Teng NN, et al.

N Engl J Med. 1991 Feb 14;324(7):429-36.

PMID:
1988827
[PubMed - indexed for MEDLINE]
Free Article
5.

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death.

Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, François B, Guy JS, Brückmann M, Rea-Neto A, Rossaint R, Perrotin D, Sablotzki A, Arkins N, Utterback BG, Macias WL; Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) Study Group.

N Engl J Med. 2005 Sep 29;353(13):1332-41.

PMID:
16192478
[PubMed - indexed for MEDLINE]
Free Article
6.

A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock.

Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA, Balk RA.

N Engl J Med. 1987 Sep 10;317(11):653-8.

PMID:
3306374
[PubMed - indexed for MEDLINE]
7.

Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial.

Dellinger RP, Tomayko JF, Angus DC, Opal S, Cupo MA, McDermott S, Ducher A, Calandra T, Cohen J; Lipid Infusion and Patient Outcomes in Sepsis (LIPOS) Investigators.

Crit Care Med. 2009 Nov;37(11):2929-38. doi: 10.1097/CCM.0b013e3181b0266c.

PMID:
19770753
[PubMed - indexed for MEDLINE]
8.

Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group.

Dhainaut JF, Tenaillon A, Hemmer M, Damas P, Le Tulzo Y, Radermacher P, Schaller MD, Sollet JP, Wolff M, Holzapfel L, Zeni F, Vedrinne JM, de Vathaire F, Gourlay ML, Guinot P, Mira JP.

Crit Care Med. 1998 Dec;26(12):1963-71.

PMID:
9875905
[PubMed - indexed for MEDLINE]
9.

High-dose corticosteroids in patients with the adult respiratory distress syndrome.

Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, Sibbald WJ, Kariman K, Higgins S, Bradley R, Metz CA, et al.

N Engl J Med. 1987 Dec 17;317(25):1565-70.

PMID:
3317054
[PubMed - indexed for MEDLINE]
10.
11.

Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group.

Niewoehner DE, Erbland ML, Deupree RH, Collins D, Gross NJ, Light RW, Anderson P, Morgan NA.

N Engl J Med. 1999 Jun 24;340(25):1941-7.

PMID:
10379017
[PubMed - indexed for MEDLINE]
Free Article
12.

Mitoxantrone: a review of its use in multiple sclerosis.

Scott LJ, Figgitt DP.

CNS Drugs. 2004;18(6):379-96. Review.

PMID:
15089110
[PubMed - indexed for MEDLINE]
13.

Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome.

Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA.

Chest. 1987 Dec;92(6):1032-6. Erratum in: Chest 1988 Aug;94(2):448.

PMID:
3315478
[PubMed - indexed for MEDLINE]
14.

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis.

Rice TW, Wheeler AP, Bernard GR, Vincent JL, Angus DC, Aikawa N, Demeyer I, Sainati S, Amlot N, Cao C, Ii M, Matsuda H, Mouri K, Cohen J.

Crit Care Med. 2010 Aug;38(8):1685-94. doi: 10.1097/CCM.0b013e3181e7c5c9.

PMID:
20562702
[PubMed - indexed for MEDLINE]
15.

Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock.

Angstwurm MW, Engelmann L, Zimmermann T, Lehmann C, Spes CH, Abel P, Strauss R, Meier-Hellmann A, Insel R, Radke J, Schüttler J, Gärtner R.

Crit Care Med. 2007 Jan;35(1):118-26.

PMID:
17095947
[PubMed - indexed for MEDLINE]
16.

Multicenter evaluation of a human monoclonal antibody to Enterobacteriaceae common antigen in patients with Gram-negative sepsis.

Albertson TE, Panacek EA, MacArthur RD, Johnson SB, Benjamin E, Matuschak GM, Zaloga G, Maki D, Silverstein J, Tobias JK, Haenftling K, Black G, Cowens JW; MAB-T88 Sepsis Study Group.

Crit Care Med. 2003 Feb;31(2):419-27.

PMID:
12576946
[PubMed - indexed for MEDLINE]
17.

Termination of the Department of Veterans Affairs Cooperative Study of steroid therapy for systemic sepsis.

Peduzzi P.

Control Clin Trials. 1991 Jun;12(3):395-407.

PMID:
1651210
[PubMed - indexed for MEDLINE]
18.

A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study.

Bracken MB, Shepard MJ, Collins WF, Holford TR, Young W, Baskin DS, Eisenberg HM, Flamm E, Leo-Summers L, Maroon J, et al.

N Engl J Med. 1990 May 17;322(20):1405-11.

PMID:
2278545
[PubMed - indexed for MEDLINE]
Free Article
19.

Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group.

Opal SM, Fisher CJ Jr, Dhainaut JF, Vincent JL, Brase R, Lowry SF, Sadoff JC, Slotman GJ, Levy H, Balk RA, Shelly MP, Pribble JP, LaBrecque JF, Lookabaugh J, Donovan H, Dubin H, Baughman R, Norman J, DeMaria E, Matzel K, Abraham E, Seneff M.

Crit Care Med. 1997 Jul;25(7):1115-24.

PMID:
9233735
[PubMed - indexed for MEDLINE]
20.

Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study.

Abraham E, Reinhart K, Svoboda P, Seibert A, Olthoff D, Dal Nogare A, Postier R, Hempelmann G, Butler T, Martin E, Zwingelstein C, Percell S, Shu V, Leighton A, Creasey AA.

Crit Care Med. 2001 Nov;29(11):2081-9.

PMID:
11700399
[PubMed - indexed for MEDLINE]

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