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Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence.

Ono Y, Fujii T, Igarashi K, Kuno T, Tanaka C, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1989 Jul;86(13):4868-71.


Protein kinase C contains two phorbol ester binding domains.

Burns DJ, Bell RM.

J Biol Chem. 1991 Sep 25;266(27):18330-8.


Residues in the second cysteine-rich region of protein kinase C delta relevant to phorbol ester binding as revealed by site-directed mutagenesis.

Kazanietz MG, Wang S, Milne GW, Lewin NE, Liu HL, Blumberg PM.

J Biol Chem. 1995 Sep 15;270(37):21852-9.


Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

Ono Y, Fujii T, Ogita K, Kikkawa U, Igarashi K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1989 May;86(9):3099-103.


Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C.

Kaibuchi K, Fukumoto Y, Oku N, Takai Y, Arai K, Muramatsu M.

J Biol Chem. 1989 Aug 15;264(23):13489-96.


Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products.

Kazanietz MG, Bustelo XR, Barbacid M, Kolch W, Mischak H, Wong G, Pettit GR, Bruns JD, Blumberg PM.

J Biol Chem. 1994 Apr 15;269(15):11590-4.


Effector-dependent conformational changes in protein kinase C gamma through epitope mapping with inhibitory monoclonal antibodies.

Cazaubon S, Webster C, Camoin L, Strosberg AD, Parker P.

Eur J Biochem. 1990 Dec 27;194(3):799-804.


Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors.

Areces LB, Kazanietz MG, Blumberg PM.

J Biol Chem. 1994 Jul 29;269(30):19553-8.


The ultraviolet studies on protein-lipid interaction of a protein kinase C-gamma phorbol-binding domain.

Kowara R, Gryckiewicz E, Matecki A, Pawelczyk T.

Acta Biochim Pol. 1999;46(2):405-17.


Low affinity binding of phorbol esters to protein kinase C and its recombinant cysteine-rich region in the absence of phospholipids.

Kazanietz MG, Barchi JJ Jr, Omichinski JG, Blumberg PM.

J Biol Chem. 1995 Jun 16;270(24):14679-84.


Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor.

Ahmed S, Kozma R, Monfries C, Hall C, Lim HH, Smith P, Lim L.

Biochem J. 1990 Dec 15;272(3):767-73.


Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters.

Shindo M, Irie K, Masuda A, Ohigashi H, Shirai Y, Miyasaka K, Saito N.

J Biol Chem. 2003 May 16;278(20):18448-54. Epub 2003 Mar 5.


The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain.

Sakane F, Kai M, Wada I, Imai S, Kanoh H.

Biochem J. 1996 Sep 1;318 ( Pt 2):583-90.

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