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Results: 1 to 20 of 107

1.

The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity.

Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA.

Cancer Cell. 2013 Mar 18;23(3):332-46. doi: 10.1016/j.ccr.2013.02.016. Erratum in: Cancer Cell. 2013 Jun 10;23(6):853. Fazil, Ladan [corrected to Fazli, Ladan].

PMID:
23518348
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells.

Chen L, Siddiqui S, Bose S, Mooso B, Asuncion A, Bedolla RG, Vinall R, Tepper CG, Gandour-Edwards R, Shi X, Lu XH, Siddiqui J, Chinnaiyan AM, Mehra R, Devere White RW, Carraway KL 3rd, Ghosh PM.

Cancer Res. 2010 Jul 15;70(14):5994-6003. doi: 10.1158/0008-5472.CAN-09-4440. Epub 2010 Jun 29.

PMID:
20587519
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J.

Cancer Res. 2012 Jul 15;72(14):3457-62. doi: 10.1158/0008-5472.CAN-11-3892. Epub 2012 Jun 18.

PMID:
22710436
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival.

Peacock SO, Fahrenholtz CD, Burnstein KL.

Mol Endocrinol. 2012 Dec;26(12):1967-79. doi: 10.1210/me.2012-1165. Epub 2012 Sep 28.

PMID:
23023561
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancer.

Takayama K, Horie-Inoue K, Suzuki T, Urano T, Ikeda K, Fujimura T, Takahashi S, Homma Y, Ouchi Y, Inoue S.

Mol Endocrinol. 2012 May;26(5):748-61. doi: 10.1210/me.2011-1242. Epub 2012 Mar 28.

PMID:
22456197
[PubMed - indexed for MEDLINE]
7.

Angiogenin mediates androgen-stimulated prostate cancer growth and enables castration resistance.

Li S, Hu MG, Sun Y, Yoshioka N, Ibaragi S, Sheng J, Sun G, Kishimoto K, Hu GF.

Mol Cancer Res. 2013 Oct;11(10):1203-14. doi: 10.1158/1541-7786.MCR-13-0072. Epub 2013 Jul 12.

PMID:
23851444
[PubMed - indexed for MEDLINE]
8.

A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells.

Imberg-Kazdan K, Ha S, Greenfield A, Poultney CS, Bonneau R, Logan SK, Garabedian MJ.

Genome Res. 2013 Apr;23(4):581-91. doi: 10.1101/gr.144774.112. Epub 2013 Feb 12.

PMID:
23403032
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.

Linn DE, Yang X, Xie Y, Alfano A, Deshmukh D, Wang X, Shimelis H, Chen H, Li W, Xu K, Chen M, Qiu Y.

J Biol Chem. 2012 Jun 29;287(27):22959-68. doi: 10.1074/jbc.M111.338350. Epub 2012 May 14.

PMID:
22584579
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.

Whitworth H, Bhadel S, Ivey M, Conaway M, Spencer A, Hernan R, Holemon H, Gioeli D.

PLoS One. 2012;7(6):e38950. doi: 10.1371/journal.pone.0038950. Epub 2012 Jun 27.

PMID:
22761715
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions.

Decker KF, Zheng D, He Y, Bowman T, Edwards JR, Jia L.

Nucleic Acids Res. 2012 Nov;40(21):10765-79. doi: 10.1093/nar/gks888. Epub 2012 Sep 27.

PMID:
23019221
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Deubiquitinating enzyme Usp12 is a novel co-activator of the androgen receptor.

Burska UL, Harle VJ, Coffey K, Darby S, Ramsey H, O'Neill D, Logan IR, Gaughan L, Robson CN.

J Biol Chem. 2013 Nov 8;288(45):32641-50. doi: 10.1074/jbc.M113.485912. Epub 2013 Sep 21.

PMID:
24056413
[PubMed - indexed for MEDLINE]
13.

Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer.

Li B, Lu W, Yang Q, Yu X, Matusik RJ, Chen Z.

Prostate. 2014 Apr;74(4):421-32. doi: 10.1002/pros.22763. Epub 2013 Dec 17.

PMID:
24347472
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer.

Logan IR, Gaughan L, McCracken SR, Sapountzi V, Leung HY, Robson CN.

Mol Cell Biol. 2006 Sep;26(17):6502-10.

PMID:
16914734
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression.

Shiota M, Yokomizo A, Tada Y, Inokuchi J, Kashiwagi E, Masubuchi D, Eto M, Uchiumi T, Naito S.

Oncogene. 2010 Jan 14;29(2):237-50. doi: 10.1038/onc.2009.322. Epub 2009 Oct 5.

PMID:
19802001
[PubMed - indexed for MEDLINE]
16.

Peroxiredoxin 2 in the nucleus and cytoplasm distinctly regulates androgen receptor activity in prostate cancer cells.

Shiota M, Yokomizo A, Kashiwagi E, Takeuchi A, Fujimoto N, Uchiumi T, Naito S.

Free Radic Biol Med. 2011 Jul 1;51(1):78-87. doi: 10.1016/j.freeradbiomed.2011.04.001. Epub 2011 Apr 14.

PMID:
21539911
[PubMed - indexed for MEDLINE]
17.

p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2).

Liu T, Li Y, Gu H, Zhu G, Li J, Cao L, Li F.

J Biol Chem. 2013 Feb 1;288(5):3359-69. doi: 10.1074/jbc.M112.384289. Epub 2012 Nov 6.

PMID:
23132866
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor.

Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, Kim K, Sawyers CL.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16759-65. doi: 10.1073/pnas.1012443107. Epub 2010 Sep 7.

PMID:
20823238
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage.

Li L, Xie H, Liang L, Gao Y, Zhang D, Fang L, Lee SO, Luo J, Chen X, Wang X, Chang LS, Yeh S, Wang Y, He D, Chang C.

Carcinogenesis. 2013 Feb;34(2):257-67. doi: 10.1093/carcin/bgs337. Epub 2012 Oct 26.

PMID:
23104178
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Testosterone boosts for treatment of castration resistant prostate cancer: an experimental implementation of intermittent androgen deprivation.

Thelen P, Heinrich E, Bremmer F, Trojan L, Strauss A.

Prostate. 2013 Nov;73(15):1699-709. doi: 10.1002/pros.22711. Epub 2013 Jul 19.

PMID:
23868789
[PubMed - indexed for MEDLINE]

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