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Results: 1 to 20 of 189

1.

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay.

Kheradpour P, Ernst J, Melnikov A, Rogov P, Wang L, Zhang X, Alston J, Mikkelsen TS, Kellis M.

Genome Res. 2013 May;23(5):800-11. doi: 10.1101/gr.144899.112. Epub 2013 Mar 19.

PMID:
23512712
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay.

Melnikov A, Murugan A, Zhang X, Tesileanu T, Wang L, Rogov P, Feizi S, Gnirke A, Callan CG Jr, Kinney JB, Kellis M, Lander ES, Mikkelsen TS.

Nat Biotechnol. 2012 Feb 26;30(3):271-7. doi: 10.1038/nbt.2137.

PMID:
22371084
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs.

Starr MO, Ho MC, Gunther EJ, Tu YK, Shur AS, Goetz SE, Borok MJ, Kang V, Drewell RA.

Dev Biol. 2011 Nov 15;359(2):290-302. doi: 10.1016/j.ydbio.2011.07.028. Epub 2011 Jul 28.

PMID:
21821017
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mapping and analysis of chromatin state dynamics in nine human cell types.

Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE.

Nature. 2011 May 5;473(7345):43-9. doi: 10.1038/nature09906. Epub 2011 Mar 23.

PMID:
21441907
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes.

Zhang Q, Reddy PM, Yu CY, Bastiani C, Higgs D, Stamatoyannopoulos G, Papayannopoulou T, Shen CK.

Mol Cell Biol. 1993 Apr;13(4):2298-308.

PMID:
8455611
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Identification of biologically relevant enhancers in human erythroid cells.

Su MY, Steiner LA, Bogardus H, Mishra T, Schulz VP, Hardison RC, Gallagher PG.

J Biol Chem. 2013 Mar 22;288(12):8433-44. doi: 10.1074/jbc.M112.413260. Epub 2013 Jan 22.

PMID:
23341446
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types.

Ernst J, Kellis M.

Genome Res. 2013 Jul;23(7):1142-54. doi: 10.1101/gr.144840.112. Epub 2013 Apr 17.

PMID:
23595227
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gamma-globin gene promoter elements required for interaction with globin enhancers.

Langdon SD, Kaufman RE.

Blood. 1998 Jan 1;91(1):309-18.

PMID:
9414299
[PubMed - indexed for MEDLINE]
Free Article
10.

The in vivo dissection of direct RFX-target gene promoters in C. elegans reveals a novel cis-regulatory element, the C-box.

Burghoorn J, Piasecki BP, Crona F, Phirke P, Jeppsson KE, Swoboda P.

Dev Biol. 2012 Aug 15;368(2):415-26. doi: 10.1016/j.ydbio.2012.05.033. Epub 2012 Jun 5.

PMID:
22683808
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Transcriptional control of muscle plasticity: differential regulation of troponin I genes by electrical activity.

Calvo S, Stauffer J, Nakayama M, Buonanno A.

Dev Genet. 1996;19(2):169-81.

PMID:
8900050
[PubMed - indexed for MEDLINE]
13.

Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer.

Ceelie H, Spaargaren-Van Riel CC, De Jong M, Bertina RM, Vos HL.

J Thromb Haemost. 2003 Aug;1(8):1688-98.

PMID:
12911579
[PubMed - indexed for MEDLINE]
14.

E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer.

Coulson JM, Fiskerstrand CE, Woll PJ, Quinn JP.

Biochem J. 1999 Dec 15;344 Pt 3:961-70.

PMID:
10585887
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

ATBF1, a multiple-homeodomain zinc finger protein, selectively down-regulates AT-rich elements of the human alpha-fetoprotein gene.

Yasuda H, Mizuno A, Tamaoki T, Morinaga T.

Mol Cell Biol. 1994 Feb;14(2):1395-401.

PMID:
7507206
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control.

Burzynski GM, Reed X, Taher L, Stine ZE, Matsui T, Ovcharenko I, McCallion AS.

Genome Res. 2012 Nov;22(11):2278-89. doi: 10.1101/gr.139717.112. Epub 2012 Jul 3.

PMID:
22759862
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity.

Kaufman CK, Sinha S, Bolotin D, Fan J, Fuchs E.

Mol Cell Biol. 2002 Jun;22(12):4293-308.

PMID:
12024040
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Identification and functional analysis of a novel human CYP2E1 far upstream enhancer.

Shadley JD, Divakaran K, Munson K, Hines RN, Douglas K, McCarver DG.

Mol Pharmacol. 2007 Jun;71(6):1630-9. Epub 2007 Mar 12.

PMID:
17353354
[PubMed - indexed for MEDLINE]
Free Article
19.

The role of viral enhancer "core" motif-related sequences in regulating T cell receptor-gamma and -delta gene expression.

Hsiang YH, Spencer D, Wang S, Speck NA, Raulet DH.

J Immunol. 1993 May 1;150(9):3905-16.

PMID:
8473739
[PubMed - indexed for MEDLINE]

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