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Results: 1 to 20 of 142

1.

Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity.

Krosch TC, Sangwan V, Banerjee S, Mujumdar N, Dudeja V, Saluja AK, Vickers SM.

Am J Surg. 2013 Apr;205(4):387-96. doi: 10.1016/j.amjsurg.2013.01.008. Epub 2013 Feb 19.

PMID:
23428154
[PubMed - indexed for MEDLINE]
2.

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo.

Antonoff MB, Chugh R, Borja-Cacho D, Dudeja V, Clawson KA, Skube SJ, Sorenson BS, Saltzman DA, Vickers SM, Saluja AK.

Surgery. 2009 Aug;146(2):282-90. doi: 10.1016/j.surg.2009.04.023.

PMID:
19628086
[PubMed - indexed for MEDLINE]
3.

Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways.

Mujumdar N, Mackenzie TN, Dudeja V, Chugh R, Antonoff MB, Borja-Cacho D, Sangwan V, Dawra R, Vickers SM, Saluja AK.

Gastroenterology. 2010 Aug;139(2):598-608. doi: 10.1053/j.gastro.2010.04.046. Epub 2010 Apr 29.

PMID:
20434451
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of Hsp-70 in triptolide-mediated cell death of neuroblastoma.

Antonoff MB, Chugh R, Skube SJ, Dudeja V, Borja-Cacho D, Clawson KA, Vickers SM, Saluja AK.

J Surg Res. 2010 Sep;163(1):72-8. doi: 10.1016/j.jss.2010.04.047. Epub 2010 May 20.

PMID:
20638672
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Autophagy in pancreatic cancer: an emerging mechanism of cell death.

Mujumdar N, Saluja AK.

Autophagy. 2010 Oct;6(7):997-8. doi: 10.4161/auto.6.7.13334. Epub 2010 Oct 16.

PMID:
20818166
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Antagonist effect of triptolide on AKT activation by truncated retinoid X receptor-alpha.

Lu N, Liu J, Liu J, Zhang C, Jiang F, Wu H, Chen L, Zeng W, Cao X, Yan T, Wang G, Zhou H, Lin B, Yan X, Zhang XK, Zeng JZ.

PLoS One. 2012;7(4):e35722. doi: 10.1371/journal.pone.0035722. Epub 2012 Apr 24.

PMID:
22545132
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells.

Yinjun L, Jie J, Yungui W.

Leuk Res. 2005 Jan;29(1):99-105.

PMID:
15541481
[PubMed - indexed for MEDLINE]
8.

Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells.

Chang HJ, Kim MH, Baek MK, Park JS, Chung IJ, Shin BA, Ahn BW, Jung YD.

Anticancer Res. 2007 Sep-Oct;27(5A):3411-7.

PMID:
17970088
[PubMed - indexed for MEDLINE]
Free Article
9.

Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma.

Clawson KA, Borja-Cacho D, Antonoff MB, Saluja AK, Vickers SM.

J Surg Res. 2010 Oct;163(2):244-9. doi: 10.1016/j.jss.2010.03.067. Epub 2010 Apr 25.

PMID:
20691980
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.

Jiang XH, Wong BC, Lin MC, Zhu GH, Kung HF, Jiang SH, Yang D, Lam SK.

Oncogene. 2001 Nov 29;20(55):8009-18.

PMID:
11753684
[PubMed - indexed for MEDLINE]
Free Article
11.

[Study of triptolide-induced apoptosis in MUTZ-1 cells and its allied mechanism].

Deng J, Jin J.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Jun;13(3):434-9. Chinese.

PMID:
15972136
[PubMed - indexed for MEDLINE]
12.

Triptolide inhibits proliferation and induces apoptosis of human melanoma A375 cells.

Tao Y, Zhang ML, Ma PC, Sun JF, Zhou WQ, Cao YP, Li LJ.

Asian Pac J Cancer Prev. 2012;13(4):1611-5.

PMID:
22799376
[PubMed - indexed for MEDLINE]
Free Article
13.

TRAIL and triptolide: an effective combination that induces apoptosis in pancreatic cancer cells.

Borja-Cacho D, Yokoyama Y, Chugh RK, Mujumdar NR, Dudeja V, Clawson KA, Dawra RK, Saluja AK, Vickers SM.

J Gastrointest Surg. 2010 Feb;14(2):252-60. doi: 10.1007/s11605-009-1065-6. Epub 2009 Dec 16.

PMID:
20013316
[PubMed - indexed for MEDLINE]
14.

Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation.

Shi X, Jin Y, Cheng C, Zhang H, Zou W, Zheng Q, Lu Z, Chen Q, Lai Y, Pan J.

Clin Cancer Res. 2009 Mar 1;15(5):1686-97. doi: 10.1158/1078-0432.CCR-08-2141. Epub 2009 Feb 24.

PMID:
19240172
[PubMed - indexed for MEDLINE]
Free Article
15.

Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice.

Hsu YY, Jong YJ, Tsai HH, Tseng YT, An LM, Lo YC.

Br J Pharmacol. 2012 Jun;166(3):1114-26. doi: 10.1111/j.1476-5381.2012.01829.x.

PMID:
22220673
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway.

Wu PP, Liu KC, Huang WW, Ma CY, Lin H, Yang JS, Chung JG.

Oncol Rep. 2011 Feb;25(2):551-7. doi: 10.3892/or.2010.1080. Epub 2010 Dec 8.

PMID:
21152873
[PubMed - indexed for MEDLINE]
17.

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

Phillips PA, Dudeja V, McCarroll JA, Borja-Cacho D, Dawra RK, Grizzle WE, Vickers SM, Saluja AK.

Cancer Res. 2007 Oct 1;67(19):9407-16.

PMID:
17909050
[PubMed - indexed for MEDLINE]
Free Article
18.

Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'.

Lu L, Kanwar J, Schmitt S, Cui QC, Zhang C, Zhao C, Dou QP.

Anticancer Res. 2011 Jan;31(1):1-10.

PMID:
21273574
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells.

Zhao F, Chen Y, Zeng LL, Li R, Zeng R, Wen L, Liu Y, Zhang C.

Acta Pharmacol Sin. 2010 Jun;31(6):733-40. doi: 10.1038/aps.2010.49.

PMID:
20523343
[PubMed - indexed for MEDLINE]
Free Article
20.

Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.

Banerjee S, Sangwan V, McGinn O, Chugh R, Dudeja V, Vickers SM, Saluja AK.

J Biol Chem. 2013 Nov 22;288(47):33927-38. doi: 10.1074/jbc.M113.500983. Epub 2013 Oct 15.

PMID:
24129563
[PubMed - indexed for MEDLINE]

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