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Results: 1 to 20 of 203

1.

MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments.

Hendrix CW, Chen BA, Guddera V, Hoesley C, Justman J, Nakabiito C, Salata R, Soto-Torres L, Patterson K, Minnis AM, Gandham S, Gomez K, Richardson BA, Bumpus NN.

PLoS One. 2013;8(1):e55013. doi: 10.1371/journal.pone.0055013. Epub 2013 Jan 30.

PMID:
23383037
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate.

Anton PA, Cranston RD, Kashuba A, Hendrix CW, Bumpus NN, Richardson-Harman N, Elliott J, Janocko L, Khanukhova E, Dennis R, Cumberland WG, Ju C, Carballo-Diéguez A, Mauck C, McGowan I.

AIDS Res Hum Retroviruses. 2012 Nov;28(11):1412-21. doi: 10.1089/AID.2012.0262. Epub 2012 Oct 9.

PMID:
22943559
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Adherence and acceptability in MTN 001: a randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women.

Minnis AM, Gandham S, Richardson BA, Guddera V, Chen BA, Salata R, Nakabiito C, Hoesley C, Justman J, Soto-Torres L, Patterson K, Gomez K, Hendrix CW.

AIDS Behav. 2013 Feb;17(2):737-47. doi: 10.1007/s10461-012-0333-8.

PMID:
23065145
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pharmacokinetics and topical vaginal effects of two tenofovir gels in rabbits.

Clark MR, Friend DR.

AIDS Res Hum Retroviruses. 2012 Nov;28(11):1458-66. doi: 10.1089/AID.2011.0328. Epub 2012 Apr 17.

PMID:
22394281
[PubMed - indexed for MEDLINE]
5.

Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue.

Louissaint NA, Cao YJ, Skipper PL, Liberman RG, Tannenbaum SR, Nimmagadda S, Anderson JR, Everts S, Bakshi R, Fuchs EJ, Hendrix CW.

AIDS Res Hum Retroviruses. 2013 Nov;29(11):1443-50. doi: 10.1089/AID.2013.0044. Epub 2013 May 29.

PMID:
23600365
[PubMed - indexed for MEDLINE]
6.

A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets for the prevention of HIV infection.

Gengiah TN, Baxter C, Mansoor LE, Kharsany AB, Abdool Karim SS.

Expert Opin Investig Drugs. 2012 May;21(5):695-715. doi: 10.1517/13543784.2012.667072. Epub 2012 Mar 7. Review.

PMID:
22394224
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Durable protection from vaginal simian-human immunodeficiency virus infection in macaques by tenofovir gel and its relationship to drug levels in tissue.

Dobard C, Sharma S, Martin A, Pau CP, Holder A, Kuklenyik Z, Lipscomb J, Hanson DL, Smith J, Novembre FJ, García-Lerma JG, Heneine W.

J Virol. 2012 Jan;86(2):718-25. doi: 10.1128/JVI.05842-11. Epub 2011 Nov 9.

PMID:
22072766
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques.

Nuttall J, Kashuba A, Wang R, White N, Allen P, Roberts J, Romano J.

Antimicrob Agents Chemother. 2012 Jan;56(1):103-9. doi: 10.1128/AAC.00597-11. Epub 2011 Oct 10.

PMID:
21986823
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel.

Gao Y, Katz DF.

PLoS One. 2013 Sep 11;8(9):e74404. doi: 10.1371/journal.pone.0074404. eCollection 2013.

PMID:
24040241
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The clinical pharmacology of antiretrovirals for HIV prevention.

Hendrix CW.

Curr Opin HIV AIDS. 2012 Nov;7(6):498-504. doi: 10.1097/COH.0b013e32835847ae. Review.

PMID:
22964888
[PubMed - indexed for MEDLINE]
11.

Pharmacokinetics and placental transfer of single-dose tenofovir 1% vaginal gel in term pregnancy.

Beigi R, Noguchi L, Parsons T, Macio I, Kunjara Na Ayudhya RP, Chen J, Hendrix CW, Mâsse B, Valentine M, Piper J, Watts DH.

J Infect Dis. 2011 Nov 15;204(10):1527-31. doi: 10.1093/infdis/jir562. Epub 2011 Sep 19.

PMID:
21930612
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Considerations regarding antiretroviral chemoprophylaxis in MSM.

Poynten IM, Zablotska I, Grulich AE.

Curr Opin HIV AIDS. 2012 Nov;7(6):549-56. doi: 10.1097/COH.0b013e3283582c71. Review.

PMID:
22918448
[PubMed - indexed for MEDLINE]
13.

Pharmacokinetics and safety of tenofovir in HIV-infected women during labor and their infants during the first week of life.

Mirochnick M, Taha T, Kreitchmann R, Nielsen-Saines K, Kumwenda N, Joao E, Pinto J, Santos B, Parsons T, Kearney B, Emel L, Herron C, Richardson P, Hudelson SE, Eshleman SH, George K, Fowler MG, Sato P, Mofenson L; HPTN 057 Protocol Team.

J Acquir Immune Defic Syndr. 2014 Jan 1;65(1):33-41. doi: 10.1097/QAI.0b013e3182a921eb.

PMID:
23979002
[PubMed - indexed for MEDLINE]
14.

Pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against HIV-1 infection.

Duwal S, Schütte C, von Kleist M.

PLoS One. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. Epub 2012 Jul 11. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/fb73d0f4-1cd8-481d-bddd-20439896102a.

PMID:
22808148
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A perspective on progress and gaps in HIV prevention science.

Kiser PF, Mesquita PM, Herold BC.

AIDS Res Hum Retroviruses. 2012 Nov;28(11):1373-8. doi: 10.1089/AID.2012.0277.

PMID:
22966871
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A 90-day tenofovir reservoir intravaginal ring for mucosal HIV prophylaxis.

Johnson TJ, Clark MR, Albright TH, Nebeker JS, Tuitupou AL, Clark JT, Fabian J, McCabe RT, Chandra N, Doncel GF, Friend DR, Kiser PF.

Antimicrob Agents Chemother. 2012 Dec;56(12):6272-83. doi: 10.1128/AAC.01431-12. Epub 2012 Sep 24.

PMID:
23006751
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Safety and adherence to intermittent pre-exposure prophylaxis (PrEP) for HIV-1 in African men who have sex with men and female sex workers.

Mutua G, Sanders E, Mugo P, Anzala O, Haberer JE, Bangsberg D, Barin B, Rooney JF, Mark D, Chetty P, Fast P, Priddy FH.

PLoS One. 2012;7(4):e33103. doi: 10.1371/journal.pone.0033103. Epub 2012 Apr 12.

PMID:
22511916
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Safety, adherence and acceptability of intermittent tenofovir/emtricitabine as HIV pre-exposure prophylaxis (PrEP) among HIV-uninfected Ugandan volunteers living in HIV-serodiscordant relationships: a randomized, clinical trial.

Kibengo FM, Ruzagira E, Katende D, Bwanika AN, Bahemuka U, Haberer JE, Bangsberg DR, Barin B, Rooney JF, Mark D, Chetty P, Fast P, Kamali A, Priddy FH.

PLoS One. 2013 Sep 26;8(9):e74314. doi: 10.1371/journal.pone.0074314. eCollection 2013.

PMID:
24086333
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.

Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, Kharsany AB, Sibeko S, Mlisana KP, Omar Z, Gengiah TN, Maarschalk S, Arulappan N, Mlotshwa M, Morris L, Taylor D; CAPRISA 004 Trial Group.

Science. 2010 Sep 3;329(5996):1168-74. doi: 10.1126/science.1193748. Epub 2010 Jul 19. Erratum in: Science. 2011 Jul 29;333(6042):524.

PMID:
20643915
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Antiviral activity of genital tract secretions after oral or topical tenofovir pre-exposure prophylaxis for HIV-1.

Herold BC, Dezzutti CS, Richardson BA, Marrazzo J, Mesquita PM, Carpenter C, Huber A, Louissaint N, Marzinke MA, Hillier SL, Hendrix CW.

J Acquir Immune Defic Syndr. 2014 May 1;66(1):65-73. doi: 10.1097/QAI.0000000000000110.

PMID:
24457633
[PubMed - indexed for MEDLINE]

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