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Results: 1 to 20 of 104

1.

Intestinal alkaline phosphatase inhibits the proinflammatory nucleotide uridine diphosphate.

Moss AK, Hamarneh SR, Mohamed MM, Ramasamy S, Yammine H, Patel P, Kaliannan K, Alam SN, Muhammad N, Moaven O, Teshager A, Malo NS, Narisawa S, Millán JL, Warren HS, Hohmann E, Malo MS, Hodin RA.

Am J Physiol Gastrointest Liver Physiol. 2013 Mar 15;304(6):G597-604. doi: 10.1152/ajpgi.00455.2012. Epub 2013 Jan 10.

PMID:
23306083
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.

Chen KT, Malo MS, Moss AK, Zeller S, Johnson P, Ebrahimi F, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G467-75. doi: 10.1152/ajpgi.00364.2009. Epub 2010 May 20.

PMID:
20489044
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The effect of intestinal alkaline phosphatase on intestinal epithelial cells, macrophages and chronic colitis in mice.

Lee C, Chun J, Hwang SW, Kang SJ, Im JP, Kim JS.

Life Sci. 2014 Apr 1;100(2):118-24. doi: 10.1016/j.lfs.2014.02.003. Epub 2014 Feb 16.

PMID:
24548630
[PubMed - indexed for MEDLINE]
4.

A role for intestinal alkaline phosphatase in the maintenance of local gut immunity.

Chen KT, Malo MS, Beasley-Topliffe LK, Poelstra K, Millan JL, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA.

Dig Dis Sci. 2011 Apr;56(4):1020-7. doi: 10.1007/s10620-010-1396-x. Epub 2010 Sep 16.

PMID:
20844955
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Intestinal inflammation increases the expression of the P2Y6 receptor on epithelial cells and the release of CXC chemokine ligand 8 by UDP.

Grbic DM, Degagné E, Langlois C, Dupuis AA, Gendron FP.

J Immunol. 2008 Feb 15;180(4):2659-68.

PMID:
18250478
[PubMed - indexed for MEDLINE]
Free Article
6.

Intestinal alkaline phosphatase contributes to the reduction of severe intestinal epithelial damage.

Bol-Schoenmakers M, Fiechter D, Raaben W, Hassing I, Bleumink R, Kruijswijk D, Maijoor K, Tersteeg-Zijderveld M, Brands R, Pieters R.

Eur J Pharmacol. 2010 May 10;633(1-3):71-7. doi: 10.1016/j.ejphar.2010.01.023. Epub 2010 Feb 2.

PMID:
20132812
[PubMed - indexed for MEDLINE]
7.

Impaired mucosal barrier function in the small intestine of the cystic fibrosis mouse.

De Lisle RC, Mueller R, Boyd M.

J Pediatr Gastroenterol Nutr. 2011 Oct;53(4):371-9. doi: 10.1097/MPG.0b013e318219c397.

PMID:
21970994
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Alterations of the mucosal immune system in inflammatory bowel disease.

MacDermott RP.

J Gastroenterol. 1996 Dec;31(6):907-16. Review.

PMID:
9027661
[PubMed - indexed for MEDLINE]
9.

Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates.

Malo MS, Moaven O, Muhammad N, Biswas B, Alam SN, Economopoulos KP, Gul SS, Hamarneh SR, Malo NS, Teshager A, Mohamed MM, Tao Q, Narisawa S, Millán JL, Hohmann EL, Warren HS, Robson SC, Hodin RA.

Am J Physiol Gastrointest Liver Physiol. 2014 May 15;306(10):G826-38. doi: 10.1152/ajpgi.00357.2013. Epub 2014 Apr 10.

PMID:
24722905
[PubMed - indexed for MEDLINE]
10.

Posttranslational inhibition of proinflammatory chemokine secretion in intestinal epithelial cells: implications for specific IBD indications.

Hörmannsperger G, Clavel T, Hoffmann M, Reiff C, Kelly D, Loh G, Blaut M, Hölzlwimmer G, Haller D.

J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S10-5. doi: 10.1097/MCG.0b013e3181e102c1.

PMID:
20562631
[PubMed - indexed for MEDLINE]
11.

The pro-inflammatory cytokines, IL-1beta and TNF-alpha, inhibit intestinal alkaline phosphatase gene expression.

Malo MS, Biswas S, Abedrapo MA, Yeh L, Chen A, Hodin RA.

DNA Cell Biol. 2006 Dec;25(12):684-95.

PMID:
17233117
[PubMed - indexed for MEDLINE]
12.

P2Y6 receptor contributes to neutrophil recruitment to inflamed intestinal mucosa by increasing CXC chemokine ligand 8 expression in an AP-1-dependent manner in epithelial cells.

Grbic DM, Degagné É, Larrivée JF, Bilodeau MS, Vinette V, Arguin G, Stankova J, Gendron FP.

Inflamm Bowel Dis. 2012 Aug;18(8):1456-69. doi: 10.1002/ibd.21931. Epub 2011 Nov 17.

PMID:
22095787
[PubMed - indexed for MEDLINE]
13.

Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota.

Bates JM, Akerlund J, Mittge E, Guillemin K.

Cell Host Microbe. 2007 Dec 13;2(6):371-82.

PMID:
18078689
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Intestinal alkaline phosphatase has beneficial effects in mouse models of chronic colitis.

Ramasamy S, Nguyen DD, Eston MA, Alam SN, Moss AK, Ebrahimi F, Biswas B, Mostafa G, Chen KT, Kaliannan K, Yammine H, Narisawa S, Millán JL, Warren HS, Hohmann EL, Mizoguchi E, Reinecker HC, Bhan AK, Snapper SB, Malo MS, Hodin RA.

Inflamm Bowel Dis. 2011 Feb;17(2):532-42. doi: 10.1002/ibd.21377.

PMID:
20645323
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease.

Gadaleta RM, van Erpecum KJ, Oldenburg B, Willemsen EC, Renooij W, Murzilli S, Klomp LW, Siersema PD, Schipper ME, Danese S, Penna G, Laverny G, Adorini L, Moschetta A, van Mil SW.

Gut. 2011 Apr;60(4):463-72. doi: 10.1136/gut.2010.212159. Epub 2011 Jan 17.

PMID:
21242261
[PubMed - indexed for MEDLINE]
16.

Role of ecto-NTPDases on UDP-sensitive P2Y(6) receptor activation during osteogenic differentiation of primary bone marrow stromal cells from postmenopausal women.

Noronha-Matos JB, Costa MA, Magalhães-Cardoso MT, Ferreirinha F, Pelletier J, Freitas R, Neves JM, Sévigny J, Correia-de-Sá P.

J Cell Physiol. 2012 Jun;227(6):2694-709. doi: 10.1002/jcp.23014.

PMID:
21898410
[PubMed - indexed for MEDLINE]
17.

The pyrimidinergic P2Y6 receptor mediates a novel release of proinflammatory cytokines and chemokines in monocytic cells stimulated with UDP.

Cox MA, Gomes B, Palmer K, Du K, Wiekowski M, Wilburn B, Petro M, Chou CC, Desquitado C, Schwarz M, Lunn C, Lundell D, Narula SK, Zavodny PJ, Jenh CH.

Biochem Biophys Res Commun. 2005 May 6;330(2):467-73.

PMID:
15796906
[PubMed - indexed for MEDLINE]
18.

Elevated lipopolysaccharide in the colon evokes intestinal inflammation, aggravated in immune modulator-impaired mice.

Im E, Riegler FM, Pothoulakis C, Rhee SH.

Am J Physiol Gastrointest Liver Physiol. 2012 Aug 15;303(4):G490-7. doi: 10.1152/ajpgi.00120.2012. Epub 2012 Jun 21.

PMID:
22723263
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

Korcok J, Raimundo LN, Du X, Sims SM, Dixon SJ.

J Biol Chem. 2005 Apr 29;280(17):16909-15. Epub 2005 Feb 18.

PMID:
15722352
[PubMed - indexed for MEDLINE]
Free Article
20.

A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response.

Pike AF, Kramer NI, Blaauboer BJ, Seinen W, Brands R.

Biochim Biophys Acta. 2013 Dec;1832(12):2044-56. doi: 10.1016/j.bbadis.2013.07.016. Epub 2013 Jul 27.

PMID:
23899605
[PubMed - indexed for MEDLINE]

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