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Results: 1 to 20 of 94

1.

NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.

Wallez Y, Mace PD, Pasquale EB, Riedl SJ.

Genes Cancer. 2012 May;3(5-6):382-93. doi: 10.1177/1947601912460050.

PMID:
23226576
[PubMed]
Free PMC Article
2.

NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.

Mace PD, Wallez Y, Dobaczewska MK, Lee JJ, Robinson H, Pasquale EB, Riedl SJ.

Nat Struct Mol Biol. 2011 Nov 13;18(12):1381-7. doi: 10.1038/nsmb.2152.

PMID:
22081014
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases.

Vuori K, Hirai H, Aizawa S, Ruoslahti E.

Mol Cell Biol. 1996 Jun;16(6):2606-13.

PMID:
8649368
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling.

Kirsch K, Kensinger M, Hanafusa H, August A.

BMC Cell Biol. 2002 Jul 15;3:18.

PMID:
12119061
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance.

Garron ML, Arsenieva D, Zhong J, Bloom AB, Lerner A, O'Neill GM, Arold ST.

J Mol Biol. 2009 Feb 13;386(1):190-203. doi: 10.1016/j.jmb.2008.12.010. Epub 2008 Dec 13.

PMID:
19103205
[PubMed - indexed for MEDLINE]
6.

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs.

Nojima Y, Morino N, Mimura T, Hamasaki K, Furuya H, Sakai R, Sato T, Tachibana K, Morimoto C, Yazaki Y, et al.

J Biol Chem. 1995 Jun 23;270(25):15398-402.

PMID:
7541040
[PubMed - indexed for MEDLINE]
Free Article
7.

Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.

Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK.

Mol Cancer Res. 2005 Jun;3(6):307-15.

PMID:
15972849
[PubMed - indexed for MEDLINE]
Free Article
8.

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase.

Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT.

J Biol Chem. 1996 Jun 7;271(23):13649-55.

PMID:
8662921
[PubMed - indexed for MEDLINE]
Free Article
9.

T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G.

Ohashi Y, Tachibana K, Kamiguchi K, Fujita H, Morimoto C.

J Biol Chem. 1998 Mar 13;273(11):6446-51.

PMID:
9497377
[PubMed - indexed for MEDLINE]
Free Article
10.

p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.

Salgia R, Pisick E, Sattler M, Li JL, Uemura N, Wong WK, Burky SA, Hirai H, Chen LB, Griffin JD.

J Biol Chem. 1996 Oct 11;271(41):25198-203.

PMID:
8810278
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of c-SRC activity and function by the adapter protein CAS.

Burnham MR, Bruce-Staskal PJ, Harte MT, Weidow CL, Ma A, Weed SA, Bouton AH.

Mol Cell Biol. 2000 Aug;20(16):5865-78.

PMID:
10913170
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.

Manié SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, Druker BJ, Avraham H, Haghayeghi N, Sattler M, Salgia R, Griffin JD, Golemis EA, Freedman AS.

J Biol Chem. 1997 Feb 14;272(7):4230-6.

PMID:
9020138
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases.

Dail M, Kalo MS, Seddon JA, Côté JF, Vuori K, Pasquale EB.

J Biol Chem. 2004 Oct 1;279(40):41892-902. Epub 2004 Jul 22.

PMID:
15272013
[PubMed - indexed for MEDLINE]
Free Article
16.

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.

Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, Hanks SK.

J Biol Chem. 2004 Sep 10;279(37):38331-7. Epub 2004 Jul 6.

PMID:
15247284
[PubMed - indexed for MEDLINE]
Free Article
17.

Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src.

Ruest PJ, Shin NY, Polte TR, Zhang X, Hanks SK.

Mol Cell Biol. 2001 Nov;21(22):7641-52.

PMID:
11604500
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Molecular basis for regulation of Src by the docking protein p130Cas.

Nasertorabi F, Tars K, Becherer K, Kodandapani R, Liljas L, Vuori K, Ely KR.

J Mol Recognit. 2006 Jan-Feb;19(1):30-8.

PMID:
16245368
[PubMed - indexed for MEDLINE]
19.

Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy.

Kovacic-Milivojević B, Roediger F, Almeida EA, Damsky CH, Gardner DG, Ilić D.

Mol Biol Cell. 2001 Aug;12(8):2290-307.

PMID:
11514617
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB.

Oncogene. 2001 Feb 22;20(8):951-61.

PMID:
11314030
[PubMed - indexed for MEDLINE]
Free Article
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