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Results: 1 to 20 of 96

1.

The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Astermark J, Donfield SM, Gomperts ED, Schwarz J, Menius ED, Pavlova A, Oldenburg J, Kessing B, DiMichele DM, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Blood. 2013 Feb 21;121(8):1446-54. doi: 10.1182/blood-2012-06-434803. Epub 2012 Dec 6.

PMID:
23223434
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Unraveling the genetics of inhibitors in hemophilia.

Gouw SC, Fijnvandraat K.

Blood. 2013 Feb 21;121(8):1250-1. doi: 10.1182/blood-2012-12-472647.

PMID:
23429985
[PubMed - indexed for MEDLINE]
Free Article
3.

The multifactorial etiology of inhibitor development in hemophilia: genetics and environment.

Gouw SC, van den Berg HM.

Semin Thromb Hemost. 2009 Nov;35(8):723-34. doi: 10.1055/s-0029-1245105. Epub 2010 Feb 18. Review.

PMID:
20169509
[PubMed - indexed for MEDLINE]
4.

F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study Combined Cohort.

Haemophilia. 2013 Jan;19(1):113-8. doi: 10.1111/hae.12004. Epub 2012 Sep 7.

PMID:
22958194
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development in hemophilia patients.

Astermark J, Berntorp E, White GC, Kroner BL; MIBS Study Group.

Haemophilia. 2001 May;7(3):267-72.

PMID:
11380630
[PubMed - indexed for MEDLINE]
6.

Prevention and prediction of inhibitor risk.

Astermark J.

Haemophilia. 2012 Jul;18 Suppl 4:38-42. doi: 10.1111/j.1365-2516.2012.02827.x.

PMID:
22726081
[PubMed - indexed for MEDLINE]
7.

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.

Repessé Y, Peyron I, Dimitrov JD, Dasgupta S, Moshai EF, Costa C, Borel-Derlon A, Guillet B, D'Oiron R, Aouba A, Rothschild C, Oldenburg J, Pavlova A, Kaveri SV, Lacroix-Desmazes S; ABIRISK consortium.

Haematologica. 2013 Oct;98(10):1650-5. doi: 10.3324/haematol.2013.084665. Epub 2013 May 28.

PMID:
23716558
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Factor VIII haplotypes in severe hemophilia A patients in India.

Pinto P, Ghosh K, Shetty S.

Ann Hematol. 2013 Jul;92(7):999-1000. doi: 10.1007/s00277-012-1658-0. Epub 2012 Dec 23. No abstract available.

PMID:
23262994
[PubMed - indexed for MEDLINE]
9.

Overview of inhibitors.

Astermark J.

Semin Hematol. 2006 Apr;43(2 Suppl 4):S3-7. Review.

PMID:
16690373
[PubMed - indexed for MEDLINE]
10.

Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study.

Gouw SC, van der Bom JG, Auerswald G, Ettinghausen CE, Tedgård U, van den Berg HM.

Blood. 2007 Jun 1;109(11):4693-7. Epub 2007 Jan 11.

PMID:
17218379
[PubMed - indexed for MEDLINE]
Free Article
11.

Immune response to FVIII in hemophilia A: an overview of risk factors.

Ghosh K, Shetty S.

Clin Rev Allergy Immunol. 2009 Oct;37(2):58-66. doi: 10.1007/s12016-009-8118-1. Review.

PMID:
19148784
[PubMed - indexed for MEDLINE]
12.

The Malmö International Brother Study (MIBS). Genetic defects and inhibitor development in siblings with severe hemophilia A.

Astermark J, Oldenburg J, Escobar M, White GC 2nd, Berntorp E; Malmö International Brother Study study group.

Haematologica. 2005 Jul;90(7):924-31.

PMID:
15996930
[PubMed - indexed for MEDLINE]
Free Article
13.

Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A.

Gouw SC, van den Berg HM, le Cessie S, van der Bom JG.

J Thromb Haemost. 2007 Jul;5(7):1383-90. Epub 2007 Apr 20.

PMID:
17456190
[PubMed - indexed for MEDLINE]
14.

Age at first treatment and immune tolerance to factor VIII in severe hemophilia.

van der Bom JG, Mauser-Bunschoten EP, Fischer K, van den Berg HM.

Thromb Haemost. 2003 Mar;89(3):475-9.

PMID:
12624630
[PubMed - indexed for MEDLINE]
15.

Immune regulatory gene polymorphisms as predisposing risk factors for the development of factor VIII inhibitors in Indian severe haemophilia A patients.

Pinto P, Ghosh K, Shetty S.

Haemophilia. 2012 Sep;18(5):794-7. doi: 10.1111/j.1365-2516.2012.02845.x. Epub 2012 May 28.

PMID:
22630053
[PubMed - indexed for MEDLINE]
16.

Antibody formation and specificity in Bethesda-negative brother pairs with haemophilia A.

Klintman J, Hillarp A, Donfield S, Berntorp E, Astermark J.

Haemophilia. 2013 Jan;19(1):106-12. doi: 10.1111/j.1365-2516.2012.02903.x. Epub 2012 Jul 5.

PMID:
22762454
[PubMed - indexed for MEDLINE]
17.

Influence of the type of F8 gene mutation on inhibitor development in a single centre cohort of severe haemophilia A patients.

Gouw SC, Van Der Bom JG, Van Den Berg HM, Zewald RA, Ploos Van Amstel JK, Mauser-Bunschoten EP.

Haemophilia. 2011 Mar;17(2):275-81. doi: 10.1111/j.1365-2516.2010.02420.x. Epub 2010 Nov 11.

PMID:
21070499
[PubMed - indexed for MEDLINE]
18.

Incidence of inhibitors in a cohort of 838 males with hemophilia A previously treated with factor VIII concentrates.

Kempton CL, Soucie JM, Abshire TC.

J Thromb Haemost. 2006 Dec;4(12):2576-81. Epub 2006 Sep 26. Erratum in: J Thromb Haemost. 2007 Mar;5(3):657.

PMID:
17002659
[PubMed - indexed for MEDLINE]
19.

Inhibitors in childhood hemophilia A: genetic and treatment-related risk factors for development and eradication.

DiMichele DM.

Pediatr Blood Cancer. 2013;60 Suppl 1:S30-3. doi: 10.1002/pbc.24338. Epub 2012 Oct 25. Review.

PMID:
23109404
[PubMed - indexed for MEDLINE]
20.

Environmental and genetic factors influencing inhibitor development.

Oldenburg J, Schröder J, Brackmann HH, Müller-Reible C, Schwaab R, Tuddenham E.

Semin Hematol. 2004 Jan;41(1 Suppl 1):82-8. Review.

PMID:
14872427
[PubMed - indexed for MEDLINE]
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