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The superhealing MRL background improves muscular dystrophy.

Heydemann A, Swaggart KA, Kim GH, Holley-Cuthrell J, Hadhazy M, McNally EM.

Skelet Muscle. 2012 Dec 5;2(1):26. doi: 10.1186/2044-5040-2-26.


Biochemical and Functional Comparisons of mdx and Sgcg (-/-) Muscular Dystrophy Mouse Models.

Roberts NW, Holley-Cuthrell J, Gonzalez-Vega M, Mull AJ, Heydemann A.

Biomed Res Int. 2015;2015:131436. doi: 10.1155/2015/131436. Epub 2015 May 3.


Cardiac function in muscular dystrophy associates with abdominal muscle pathology.

Gardner BB, Swaggart KA, Kim G, Watson S, McNally EM.

J Neuromuscul Dis. 2015;2(1):39-49.


Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy.

Goldstein JA, Bogdanovich S, Beiriger A, Wren LM, Rossi AE, Gao QQ, Gardner BB, Earley JU, Molkentin JD, McNally EM.

Hum Mol Genet. 2014 Dec 20;23(25):6722-31. doi: 10.1093/hmg/ddu390. Epub 2014 Jul 28.


Increased AMP-activated protein kinase in skeletal muscles of Murphy Roth Large mice and its potential role in altered metabolism.

Berhanu TK, Holley-Cuthrell J, Roberts NW, Mull AJ, Heydemann A.

Physiol Rep. 2014 Mar 20;2(3):e00252. doi: 10.1002/phy2.252. Print 2014.


Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair.

Swaggart KA, Demonbreun AR, Vo AH, Swanson KE, Kim EY, Fahrenbach JP, Holley-Cuthrell J, Eskin A, Chen Z, Squire K, Heydemann A, Palmer AA, Nelson SF, McNally EM.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6004-9. doi: 10.1073/pnas.1324242111. Epub 2014 Apr 9.


Modifiers of heart and muscle function: where genetics meets physiology.

Swaggart KA, McNally EM.

Exp Physiol. 2014 Apr;99(4):621-6. doi: 10.1113/expphysiol.2013.075887. Epub 2013 Nov 8. Review.


A new model of experimental fibrosis in hindlimb skeletal muscle of adult mdx mouse mimicking muscular dystrophy.

Desguerre I, Arnold L, Vignaud A, Cuvellier S, Yacoub-Youssef H, Gherardi RK, Chelly J, Chretien F, Mounier R, Ferry A, Chazaud B.

Muscle Nerve. 2012 Jun;45(6):803-14. doi: 10.1002/mus.23341.


Interplay between heart and skeletal muscle disease in heart failure: the 2011 George E. Brown Memorial Lecture.

McNally EM, Goldstein JA.

Circ Res. 2012 Mar 2;110(5):749-54. doi: 10.1161/CIRCRESAHA.111.256776.


Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.

Chun JL, O'Brien R, Berry SE.

Neuromuscul Disord. 2012 Apr;22(4):368-79. doi: 10.1016/j.nmd.2011.07.003. Epub 2012 Jan 21.


Distinct genetic regions modify specific muscle groups in muscular dystrophy.

Swaggart KA, Heydemann A, Palmer AA, McNally EM.

Physiol Genomics. 2011 Jan 7;43(1):24-31. doi: 10.1152/physiolgenomics.00172.2010. Epub 2010 Oct 19.


Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.

Guerron AD, Rawat R, Sali A, Spurney CF, Pistilli E, Cha HJ, Pandey GS, Gernapudi R, Francia D, Farajian V, Escolar DM, Bossi L, Becker M, Zerr P, de la Porte S, Gordish-Dressman H, Partridge T, Hoffman EP, Nagaraju K.

PLoS One. 2010 Jun 21;5(6):e11220. doi: 10.1371/journal.pone.0011220.


Quantitative trait locus analysis of ovarian cysts derived from rete ovarii in MRL/MpJ mice.

Lee SH, Ichii O, Otsuka S, Hashimoto Y, Kon Y.

Mamm Genome. 2010 Apr;21(3-4):162-71. doi: 10.1007/s00335-010-9254-x. Epub 2010 Feb 25.


Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse.

Spurney CF, Cha HJ, Sali A, Pandey GS, Pistilli E, Guerron AD, Gordish-Dressman H, Hoffman EP, Nagaraju K.

PLoS One. 2010 Jan 29;5(1):e8976. doi: 10.1371/journal.pone.0008976.


Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice.

Heydemann A, Ceco E, Lim JE, Hadhazy M, Ryder P, Moran JL, Beier DR, Palmer AA, McNally EM.

J Clin Invest. 2009 Dec;119(12):3703-12. doi: 10.1172/JCI39845. Epub 2009 Nov 2. Erratum in: J Clin Invest. 2010 Feb;120(2):645.


Genetic manipulation of dysferlin expression in skeletal muscle: novel insights into muscular dystrophy.

Millay DP, Maillet M, Roche JA, Sargent MA, McNally EM, Bloch RJ, Molkentin JD.

Am J Pathol. 2009 Nov;175(5):1817-23. doi: 10.2353/ajpath.2009.090107. Epub 2009 Oct 15.


Overexpression of Galgt2 reduces dystrophic pathology in the skeletal muscles of alpha sarcoglycan-deficient mice.

Xu R, DeVries S, Camboni M, Martin PT.

Am J Pathol. 2009 Jul;175(1):235-47. doi: 10.2353/ajpath.2009.080967. Epub 2009 Jun 4.


Sarcolemmal neuronal nitric oxide synthase defect in limb-girdle muscular dystrophy: an adverse modulating factor in the disease course?

Fanin M, Tasca E, Nascimbeni AC, Angelini C.

J Neuropathol Exp Neurol. 2009 Apr;68(4):383-90. doi: 10.1097/NEN.0b013e31819cd612.


Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models.

Iwata Y, Katanosaka Y, Arai Y, Shigekawa M, Wakabayashi S.

Hum Mol Genet. 2009 Mar 1;18(5):824-34. doi: 10.1093/hmg/ddn408. Epub 2008 Dec 2.


Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone.

Huebner KD, Jassal DS, Halevy O, Pines M, Anderson JE.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1550-61. doi: 10.1152/ajpheart.01253.2007. Epub 2008 Feb 8.

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