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Results: 1 to 20 of 224

1.

Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.

Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29.

PMID:
23202365
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells.

Woo CH, Shishido T, McClain C, Lim JH, Li JD, Yang J, Yan C, Abe J.

Circ Res. 2008 Mar 14;102(5):538-45. doi: 10.1161/CIRCRESAHA.107.156877. Epub 2008 Jan 24.

PMID:
18218985
[PubMed - indexed for MEDLINE]
Free Article
3.

The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 ligase PIAS1.

Li S, Yang C, Hong Y, Bi H, Zhao F, Liu Y, Ao X, Pang P, Xing X, Chang AK, Xiao L, Zhang Y, Wu H.

Biol Cell. 2012 May;104(5):287-96. doi: 10.1111/boc.201100116. Epub 2012 Mar 7.

PMID:
22283414
[PubMed - indexed for MEDLINE]
4.

Protein inhibitor of activated STAT 1 (PIAS1) is identified as the SUMO E3 ligase of CCAAT/enhancer-binding protein β (C/EBPβ) during adipogenesis.

Liu Y, Zhang YD, Guo L, Huang HY, Zhu H, Huang JX, Liu Y, Zhou SR, Dang YJ, Li X, Tang QQ.

Mol Cell Biol. 2013 Nov;33(22):4606-17. doi: 10.1128/MCB.00723-13. Epub 2013 Sep 23.

PMID:
24061474
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes.

Lee JH, Park SM, Kim OS, Lee CS, Woo JH, Park SJ, Joe EH, Jou I.

Mol Cell. 2009 Sep 24;35(6):806-17. doi: 10.1016/j.molcel.2009.07.021.

PMID:
19782030
[PubMed - indexed for MEDLINE]
Free Article
6.

De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.

Heo KS, Chang E, Le NT, Cushman H, Yeh ET, Fujiwara K, Abe J.

Circ Res. 2013 Mar 15;112(6):911-23. doi: 10.1161/CIRCRESAHA.111.300179. Epub 2013 Feb 4.

PMID:
23381569
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Targeting the PIAS1 SUMO ligase pathway to control inflammation.

Liu B, Shuai K.

Trends Pharmacol Sci. 2008 Oct;29(10):505-9. doi: 10.1016/j.tips.2008.07.008. Epub 2008 Aug 26.

PMID:
18755518
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.

Jennewein C, Kuhn AM, Schmidt MV, Meilladec-Jullig V, von Knethen A, Gonzalez FJ, Brüne B.

J Immunol. 2008 Oct 15;181(8):5646-52.

PMID:
18832723
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity.

Liu B, Yang Y, Chernishof V, Loo RR, Jang H, Tahk S, Yang R, Mink S, Shultz D, Bellone CJ, Loo JA, Shuai K.

Cell. 2007 Jun 1;129(5):903-14.

PMID:
17540171
[PubMed - indexed for MEDLINE]
Free Article
10.

The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death.

Leitao BB, Jones MC, Brosens JJ.

FASEB J. 2011 Oct;25(10):3416-25. doi: 10.1096/fj.11-186346. Epub 2011 Jun 15.

PMID:
21676946
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The transcriptional repression activity of KyoT2 on the Notch/RBP-J pathway is regulated by PIAS1-catalyzed SUMOylation.

Wang J, Qin H, Liang J, Zhu Y, Liang L, Zheng M, Han H.

J Mol Biol. 2007 Jun 29;370(1):27-38. Epub 2007 Apr 12.

PMID:
17509614
[PubMed - indexed for MEDLINE]
12.

Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5.

Du JX, Yun CC, Bialkowska A, Yang VW.

J Biol Chem. 2007 Feb 16;282(7):4782-93. Epub 2006 Dec 18.

PMID:
17178721
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.

Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP.

Nature. 2009 Dec 17;462(7275):935-9. doi: 10.1038/nature08657.

PMID:
20016603
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory.

Chen YC, Hsu WL, Ma YL, Tai DJ, Lee EH.

J Neurosci. 2014 Jul 16;34(29):9574-89. doi: 10.1523/JNEUROSCI.4302-13.2014.

PMID:
25031400
[PubMed - indexed for MEDLINE]
Free Article
15.

The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.

Rabellino A, Carter B, Konstantinidou G, Wu SY, Rimessi A, Byers LA, Heymach JV, Girard L, Chiang CM, Teruya-Feldstein J, Scaglioni PP.

Cancer Res. 2012 May 1;72(9):2275-84. doi: 10.1158/0008-5472.CAN-11-3159. Epub 2012 Mar 9.

PMID:
22406621
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation.

Mascle XH, Lussier-Price M, Cappadocia L, Estephan P, Raiola L, Omichinski JG, Aubry M.

J Biol Chem. 2013 Dec 20;288(51):36312-27. doi: 10.1074/jbc.M113.486845. Epub 2013 Oct 30.

PMID:
24174529
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors.

Cox B, Briscoe J, Ulloa F.

PLoS One. 2010 Aug 11;5(8):e11996. doi: 10.1371/journal.pone.0011996.

PMID:
20711444
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.

Liang M, Melchior F, Feng XH, Lin X.

J Biol Chem. 2004 May 28;279(22):22857-65. Epub 2004 Mar 17.

PMID:
15028714
[PubMed - indexed for MEDLINE]
Free Article
19.

High mobility group nucleosomal binding domain 2 (HMGN2) SUMOylation by the SUMO E3 ligase PIAS1 decreases the binding affinity to nucleosome core particles.

Wu J, Kim S, Kwak MS, Jeong JB, Min HJ, Yoon HG, Ahn JH, Shin JS.

J Biol Chem. 2014 Jul 18;289(29):20000-11. doi: 10.1074/jbc.M114.555425. Epub 2014 May 28.

PMID:
24872413
[PubMed - indexed for MEDLINE]
20.

Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis.

Chen P, Zhao D, Sun Y, Huang L, Zhang S, Yuan Y.

Oncol Rep. 2012 Dec;28(6):2149-55. doi: 10.3892/or.2012.2030. Epub 2012 Sep 12.

PMID:
22972521
[PubMed - indexed for MEDLINE]
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