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Results: 1 to 20 of 106

1.

The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration.

Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A.

Immunity. 2012 Dec 14;37(6):971-85. doi: 10.1016/j.immuni.2012.10.007. Epub 2012 Nov 15.

PMID:
23159437
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells.

Zhou XF, Yu J, Chang M, Zhang M, Zhou D, Cammas F, Sun SC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20083-8. doi: 10.1073/pnas.1214704109. Epub 2012 Nov 19.

PMID:
23169648
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation.

Seitan VC, Hao B, Tachibana-Konwalski K, Lavagnolli T, Mira-Bontenbal H, Brown KE, Teng G, Carroll T, Terry A, Horan K, Marks H, Adams DJ, Schatz DG, Aragon L, Fisher AG, Krangel MS, Nasmyth K, Merkenschlager M.

Nature. 2011 Aug 10;476(7361):467-71. doi: 10.1038/nature10312.

PMID:
21832993
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.

Rodewald HR, Awad K, Moingeon P, D'Adamio L, Rabinowitz D, Shinkai Y, Alt FW, Reinherz EL.

J Exp Med. 1993 Apr 1;177(4):1079-92.

PMID:
8096236
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.

Shih HY, Krangel MS.

J Exp Med. 2010 Aug 30;207(9):1835-41. doi: 10.1084/jem.20100772. Epub 2010 Aug 9.

PMID:
20696701
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

PTIP promotes chromatin changes critical for immunoglobulin class switch recombination.

Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A.

Science. 2010 Aug 20;329(5994):917-23. doi: 10.1126/science.1187942. Epub 2010 Jul 29.

PMID:
20671152
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells.

D'Cruz LM, Knell J, Fujimoto JK, Goldrath AW.

Nat Immunol. 2010 Mar;11(3):240-9. doi: 10.1038/ni.1845. Epub 2010 Feb 14. Erratum in: Nat Immunol. 2010 Jul;11(7):644.

PMID:
20154672
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS.

Blood. 2007 Mar 1;109(5):1887-96. Epub 2006 Oct 31.

PMID:
17077325
[PubMed - indexed for MEDLINE]
Free Article
9.

β-Catenin induces T-cell transformation by promoting genomic instability.

Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):391-6. doi: 10.1073/pnas.1315752111. Epub 2013 Dec 26.

PMID:
24371308
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure.

Hawwari A, Krangel MS.

J Exp Med. 2005 Aug 15;202(4):467-72. Epub 2005 Aug 8.

PMID:
16087716
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination.

Abarrategui I, Krangel MS.

EMBO J. 2007 Oct 17;26(20):4380-90. Epub 2007 Sep 20.

PMID:
17882258
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters.

Hawwari A, Bock C, Krangel MS.

Nat Immunol. 2005 May;6(5):481-9. Epub 2005 Apr 3.

PMID:
15806105
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer.

Hao B, Krangel MS.

J Immunol. 2011 Sep 1;187(5):2484-91. doi: 10.4049/jimmunol.1100468. Epub 2011 Jul 22.

PMID:
21784972
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers.

Tani-Ichi S, Satake M, Ikuta K.

Int Immunol. 2011 Sep;23(9):553-63. doi: 10.1093/intimm/dxr055. Epub 2011 Jul 12.

PMID:
21750145
[PubMed - indexed for MEDLINE]
Free Article
15.

Fidelity and infidelity in commitment to B-lymphocyte lineage development.

Rolink AG, Schaniel C, Busslinger M, Nutt SL, Melchers F.

Immunol Rev. 2000 Jun;175:104-11. Review.

PMID:
10933595
[PubMed - indexed for MEDLINE]
16.

The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.

Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.

PLoS One. 2011;6(6):e20639. doi: 10.1371/journal.pone.0020639. Epub 2011 Jun 3.

PMID:
21673984
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.

Hu T, Simmons A, Yuan J, Bender TP, Alberola-Ila J.

Nat Immunol. 2010 May;11(5):435-41. doi: 10.1038/ni.1865. Epub 2010 Apr 11.

PMID:
20383148
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.

Hathcock KS, Bowen S, Livak F, Hodes RJ.

PLoS One. 2013 Apr 23;8(4):e62188. doi: 10.1371/journal.pone.0062188. Print 2013.

PMID:
23626787
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

TCRA gene rearrangement in immature thymocytes in absence of CD3, pre-TCR, and TCR signaling.

Mancini SJ, Candéias SM, Di Santo JP, Ferrier P, Marche PN, Jouvin-Marche E.

J Immunol. 2001 Oct 15;167(8):4485-93.

PMID:
11591775
[PubMed - indexed for MEDLINE]
Free Article
20.

The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo.

Yannoutsos N, Wilson P, Yu W, Chen HT, Nussenzweig A, Petrie H, Nussenzweig MC.

J Exp Med. 2001 Aug 20;194(4):471-80.

PMID:
11514603
[PubMed - indexed for MEDLINE]
Free PMC Article

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