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Specificity of an anti-capsid antibody associated with Hepatitis B Virus-related acute liver failure.

Wu W, Chen Z, Cheng N, Watts NR, Stahl SJ, Farci P, Purcell RH, Wingfield PT, Steven AC.

J Struct Biol. 2013 Jan;181(1):53-60. doi: 10.1016/j.jsb.2012.10.004. Epub 2012 Oct 16.


Epitope diversity of hepatitis B virus capsids: quasi-equivalent variations in spike epitopes and binding of different antibodies to the same epitope.

Harris A, Belnap DM, Watts NR, Conway JF, Cheng N, Stahl SJ, Vethanayagam JG, Wingfield PT, Steven AC.

J Mol Biol. 2006 Jan 20;355(3):562-76. Epub 2005 Nov 8.


Non-canonical binding of an antibody resembling a naïve B cell receptor immunoglobulin to hepatitis B virus capsids.

Watts NR, Cardone G, Vethanayagam JG, Cheng N, Hultgren C, Stahl SJ, Steven AC, Sällberg M, Wingfield PT.

J Mol Biol. 2008 Jun 20;379(5):1119-29. doi: 10.1016/j.jmb.2008.04.009. Epub 2008 Apr 9.


B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.

Farci P, Diaz G, Chen Z, Govindarajan S, Tice A, Agulto L, Pittaluga S, Boon D, Yu C, Engle RE, Haas M, Simon R, Purcell RH, Zamboni F.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8766-71. doi: 10.1073/pnas.1003854107. Epub 2010 Apr 26.


Epitope-distal effects accompany the binding of two distinct antibodies to hepatitis B virus capsids.

Bereszczak JZ, Rose RJ, van Duijn E, Watts NR, Wingfield PT, Steven AC, Heck AJ.

J Am Chem Soc. 2013 May 1;135(17):6504-12. doi: 10.1021/ja402023x. Epub 2013 Apr 18.


Characterization of a conformational epitope on hepatitis B virus core antigen and quasiequivalent variations in antibody binding.

Conway JF, Watts NR, Belnap DM, Cheng N, Stahl SJ, Wingfield PT, Steven AC.

J Virol. 2003 Jun;77(11):6466-73.


HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis.

Missale G, Redeker A, Person J, Fowler P, Guilhot S, Schlicht HJ, Ferrari C, Chisari FV.

J Exp Med. 1993 Mar 1;177(3):751-62.


Hepatitis B virus capsid: localization of the putative immunodominant loop (residues 78 to 83) on the capsid surface, and implications for the distinction between c and e-antigens.

Conway JF, Cheng N, Zlotnick A, Stahl SJ, Wingfield PT, Belnap DM, Kanngiesser U, Noah M, Steven AC.

J Mol Biol. 1998 Jun 26;279(5):1111-21.


Cryo-EM study of Hepatitis B virus core antigen capsids decorated with antibodies from a human patient.

Kandiah E, Watts NR, Cheng N, Cardone G, Stahl SJ, Heller T, Liang TJ, Wingfield PT, Steven AC.

J Struct Biol. 2012 Jan;177(1):145-51. doi: 10.1016/j.jsb.2011.10.003. Epub 2011 Oct 25.


Specificity of humoral and cellular immune response against recombinant particles of nucleocapsid protein of human hepatitis B virus in rabbits.

Isaguliants MG, Kadoshnikov YP, Kalinina TI, Smirnov VD, Wahren B.

Biochemistry (Mosc). 1998 May;63(5):551-8.


Two distinct subtypes of hepatitis B virus-related acute liver failure are separable by quantitative serum immunoglobulin M anti-hepatitis B core antibody and hepatitis B virus DNA levels.

Dao DY, Hynan LS, Yuan HJ, Sanders C, Balko J, Attar N, Lok AS, Word RA, Lee WM; Acute Liver Failure Study Group.

Hepatology. 2012 Mar;55(3):676-84. doi: 10.1002/hep.24732. Epub 2012 Jan 31.


The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity.

Schödel F, Moriarty AM, Peterson DL, Zheng JA, Hughes JL, Will H, Leturcq DJ, McGee JS, Milich DR.

J Virol. 1992 Jan;66(1):106-14. Erratum in: J Virol 1992 Jun;66(6):3977.


Identification of a dominant immunogenic epitope of the nucleocapsid (HBc) of the hepatitis B virus.

Waters JA, Jowett TP, Thomas HC.

J Med Virol. 1986 May;19(1):79-86.


Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site.

Milich DR, McLachlan A, Thornton GB, Hughes JL.

Nature. 1987 Oct 8-14;329(6139):547-9.


Molecular basis for the high degree of antigenic cross-reactivity between hepatitis B virus capsids (HBcAg) and dimeric capsid-related protein (HBeAg): insights into the enigmatic nature of the e-antigen.

Watts NR, Vethanayagam JG, Ferns RB, Tedder RS, Harris A, Stahl SJ, Steven AC, Wingfield PT.

J Mol Biol. 2010 May 14;398(4):530-41. doi: 10.1016/j.jmb.2010.03.026. Epub 2010 Mar 20.


Immunoreactivity of HCV/HBV epitopes displayed in an epitope-presenting system.

Chen Y, Xiong X, Liu X, Li J, Wen Y, Chen Y, Dai Q, Cao Z, Yu W.

Mol Immunol. 2006 Feb;43(5):436-42. Epub 2005 Apr 2.


Characterization of minor and major antigenic regions within the hepatitis B virus nucleocapsid.

Tordjeman M, Fontan G, Rabillon V, Martin J, Trepo C, Hoffenbach A, Mabrouk K, Sabatier JM, Van Rietschoten J, Somme G.

J Med Virol. 1993 Nov;41(3):221-9.


The immune response to hepatitis B virus.

Waters JA, Pignatelli M, Brown D, O'Rourke S, Lever A, Thomas HC.

Postgrad Med J. 1987;63 Suppl 2:51-6. Review.


Hepatitis B virus core and e antigen: immune recognition and use as a vaccine carrier moiety.

Schödel F, Peterson D, Milich D.

Intervirology. 1996;39(1-2):104-10.

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