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Results: 1 to 20 of 95

1.

A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

Yamanaka K, Dorjsuren D, Eoff RL, Egli M, Maloney DJ, Jadhav A, Simeonov A, Lloyd RS.

PLoS One. 2012;7(10):e45032. doi: 10.1371/journal.pone.0045032. Epub 2012 Oct 8.

PMID:
23056190
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ.

Kasiviswanathan R, Minko IG, Lloyd RS, Copeland WC.

J Biol Chem. 2013 May 17;288(20):14247-55. doi: 10.1074/jbc.M113.458802. Epub 2013 Mar 30.

PMID:
23543747
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta.

Minko IG, Washington MT, Kanuri M, Prakash L, Prakash S, Lloyd RS.

J Biol Chem. 2003 Jan 10;278(2):784-90. Epub 2002 Oct 24.

PMID:
12401796
[PubMed - indexed for MEDLINE]
Free Article
4.

Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.

Suzuki N, Ohashi E, Hayashi K, Ohmori H, Grollman AP, Shibutani S.

Biochemistry. 2001 Dec 18;40(50):15176-83.

PMID:
11735400
[PubMed - indexed for MEDLINE]
5.

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S.

Biochemistry. 2002 May 14;41(19):6100-6.

PMID:
11994005
[PubMed - indexed for MEDLINE]
6.

Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

Minko IG, Kozekov ID, Harris TM, Rizzo CJ, Lloyd RS, Stone MP.

Chem Res Toxicol. 2009 May;22(5):759-78. doi: 10.1021/tx9000489. Review.

PMID:
19397281
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.

Sassa A, Niimi N, Fujimoto H, Katafuchi A, Grúz P, Yasui M, Gupta RC, Johnson F, Ohta T, Nohmi T.

Mutat Res. 2011 Jan 10;718(1-2):10-7. doi: 10.1016/j.mrgentox.2010.11.002. Epub 2010 Nov 13.

PMID:
21078407
[PubMed - indexed for MEDLINE]
8.

Replication bypass of N2-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι.

Klug AR, Harbut MB, Lloyd RS, Minko IG.

Chem Res Toxicol. 2012 Mar 19;25(3):755-62. doi: 10.1021/tx300011w. Epub 2012 Feb 29.

PMID:
22332732
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links.

Yamanaka K, Minko IG, Takata K, Kolbanovskiy A, Kozekov ID, Wood RD, Rizzo CJ, Lloyd RS.

Chem Res Toxicol. 2010 Mar 15;23(3):689-95. doi: 10.1021/tx900449u.

PMID:
20102227
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ.

You C, Swanson AL, Dai X, Yuan B, Wang J, Wang Y.

J Biol Chem. 2013 Oct 4;288(40):28548-56. doi: 10.1074/jbc.M113.480459. Epub 2013 Aug 21.

PMID:
23965998
[PubMed - indexed for MEDLINE]
11.

Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links.

Minko IG, Harbut MB, Kozekov ID, Kozekova A, Jakobs PM, Olson SB, Moses RE, Harris TM, Rizzo CJ, Lloyd RS.

J Biol Chem. 2008 Jun 20;283(25):17075-82. doi: 10.1074/jbc.M801238200. Epub 2008 Apr 22.

PMID:
18434313
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Translesion synthesis past equine estrogen-derived 2'-deoxyadenosine DNA adducts by human DNA polymerases eta and kappa.

Yasui M, Laxmi YR, Ananthoju SR, Suzuki N, Kim SY, Shibutani S.

Biochemistry. 2006 May 16;45(19):6187-94.

PMID:
16681391
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.

Yasui M, Dong H, Bonala RR, Suzuki N, Ohmori H, Hanaoka F, Johnson F, Grollman AP, Shibutani S.

Biochemistry. 2004 Nov 30;43(47):15005-13.

PMID:
15554708
[PubMed - indexed for MEDLINE]
14.

Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells.

Yang IY, Miller H, Wang Z, Frank EG, Ohmori H, Hanaoka F, Moriya M.

J Biol Chem. 2003 Apr 18;278(16):13989-94. Epub 2003 Feb 12.

PMID:
12584190
[PubMed - indexed for MEDLINE]
Free Article
15.

Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.

Minko IG, Yamanaka K, Kozekov ID, Kozekova A, Indiani C, O'Donnell ME, Jiang Q, Goodman MF, Rizzo CJ, Lloyd RS.

Chem Res Toxicol. 2008 Oct;21(10):1983-90. doi: 10.1021/tx800174a. Epub 2008 Sep 13.

PMID:
18788757
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Translesion synthesis past tamoxifen-derived DNA adducts by human DNA polymerases eta and kappa.

Yasui M, Suzuki N, Laxmi YR, Shibutani S.

Biochemistry. 2006 Oct 3;45(39):12167-74.

PMID:
17002316
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Translesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo.

Lee DH, Pfeifer GP.

Mutat Res. 2008 May 10;641(1-2):19-26. doi: 10.1016/j.mrfmmm.2008.02.006. Epub 2008 Feb 15.

PMID:
18359049
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa.

Suzuki N, Itoh S, Poon K, Masutani C, Hanaoka F, Ohmori H, Yoshizawa I, Shibutani S.

Biochemistry. 2004 May 25;43(20):6304-11.

PMID:
15147214
[PubMed - indexed for MEDLINE]
19.

A role for polymerase eta in the cellular tolerance to cisplatin-induced damage.

Albertella MR, Green CM, Lehmann AR, O'Connor MJ.

Cancer Res. 2005 Nov 1;65(21):9799-806.

PMID:
16267001
[PubMed - indexed for MEDLINE]
Free Article
20.

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site.

Hashimoto K, Cho Y, Yang IY, Akagi J, Ohashi E, Tateishi S, de Wind N, Hanaoka F, Ohmori H, Moriya M.

J Biol Chem. 2012 Mar 16;287(12):9613-22. doi: 10.1074/jbc.M111.331728. Epub 2012 Feb 2.

PMID:
22303021
[PubMed - indexed for MEDLINE]
Free PMC Article

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