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Items: 1 to 20 of 87

1.

A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function.

Araya CL, Fowler DM, Chen W, Muniez I, Kelly JW, Fields S.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16858-63. doi: 10.1073/pnas.1209751109. Epub 2012 Oct 3.

2.

How protein stability and new functions trade off.

Tokuriki N, Stricher F, Serrano L, Tawfik DS.

PLoS Comput Biol. 2008 Feb 29;4(2):e1000002. doi: 10.1371/journal.pcbi.1000002.

3.

Influence of hPin1 WW N-terminal domain boundaries on function, protein stability, and folding.

Jäger M, Nguyen H, Dendle M, Gruebele M, Kelly JW.

Protein Sci. 2007 Jul;16(7):1495-501.

4.

Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: validation and mechanisms.

Monsellier E, Bedouelle H.

J Mol Biol. 2006 Sep 22;362(3):580-93. Epub 2006 Jul 28.

PMID:
16926023
5.

Sequence determinants of thermodynamic stability in a WW domain--an all-beta-sheet protein.

Jäger M, Dendle M, Kelly JW.

Protein Sci. 2009 Aug;18(8):1806-13. doi: 10.1002/pro.172.

6.

Structure-based mutant stability predictions on proteins of unknown structure.

Gonnelli G, Rooman M, Dehouck Y.

J Biotechnol. 2012 Oct 31;161(3):287-93. doi: 10.1016/j.jbiotec.2012.06.020. Epub 2012 Jul 8.

PMID:
22782143
7.

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins.

Olivera-Nappa A, Andrews BA, Asenjo JA.

BMC Bioinformatics. 2011 Apr 27;12:122. doi: 10.1186/1471-2105-12-122.

10.

Protein promiscuity: drug resistance and native functions--HIV-1 case.

Fernández A, Tawfik DS, Berkhout B, Sanders R, Kloczkowski A, Sen T, Jernigan B.

J Biomol Struct Dyn. 2005 Jun;22(6):615-24.

PMID:
15842167
11.

A three-state prediction of single point mutations on protein stability changes.

Capriotti E, Fariselli P, Rossi I, Casadio R.

BMC Bioinformatics. 2008 Mar 26;9 Suppl 2:S6. doi: 10.1186/1471-2105-9-S2-S6.

12.

Optimizing protein stability in vivo.

Foit L, Morgan GJ, Kern MJ, Steimer LR, von Hacht AA, Titchmarsh J, Warriner SL, Radford SE, Bardwell JC.

Mol Cell. 2009 Dec 11;36(5):861-71. doi: 10.1016/j.molcel.2009.11.022.

13.
14.

The relationship between conservation, thermodynamic stability, and function in the SH3 domain hydrophobic core.

Di Nardo AA, Larson SM, Davidson AR.

J Mol Biol. 2003 Oct 24;333(3):641-55.

PMID:
14556750
15.

Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability.

Chen J, Lu Z, Sakon J, Stites WE.

J Mol Biol. 2000 Oct 20;303(2):125-30.

PMID:
11023780
16.

The linear interaction energy method for the prediction of protein stability changes upon mutation.

Wickstrom L, Gallicchio E, Levy RM.

Proteins. 2012 Jan;80(1):111-25. doi: 10.1002/prot.23168. Epub 2011 Oct 31.

17.

Engineering proteins with tunable thermodynamic and kinetic stabilities.

Pey AL, Rodriguez-Larrea D, Bomke S, Dammers S, Godoy-Ruiz R, Garcia-Mira MM, Sanchez-Ruiz JM.

Proteins. 2008 Apr;71(1):165-74.

PMID:
17932922
18.

Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein.

Schuler B, Fürst F, Osterroth F, Steinbacher S, Huber R, Seckler R.

Proteins. 2000 Apr 1;39(1):89-101.

PMID:
10737931
19.

Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease.

McCutchen SL, Lai Z, Miroy GJ, Kelly JW, Colón W.

Biochemistry. 1995 Oct 17;34(41):13527-36.

PMID:
7577941
20.
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