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Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials.

Mexas AM, Graf EH, Pace MJ, Yu JJ, Papasavvas E, Azzoni L, Busch MP, Di Mascio M, Foulkes AS, Migueles SA, Montaner LJ, O'Doherty U.

AIDS. 2012 Nov 28;26(18):2295-306. doi: 10.1097/QAD.0b013e32835a5c2f.


Ongoing Trials.

[No authors listed]

Hematol Oncol. 2015 Jun;33 Suppl 1:322-32. doi: 10.1002/hon.2230. No abstract available.


HIV reservoirs as obstacles and opportunities for an HIV cure.

Chun TW, Moir S, Fauci AS.

Nat Immunol. 2015 May 19;16(6):584-9. doi: 10.1038/ni.3152.


Eradication of HIV-1 from CNS reservoirs: current strategies and future priorities.

Joseph J.

J Neurovirol. 2015 Jun;21(3):219-21. doi: 10.1007/s13365-015-0337-z. Epub 2015 May 5. No abstract available.


Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission.

Chéret A, Bacchus-Souffan C, Avettand-Fenoël V, Mélard A, Nembot G, Blanc C, Samri A, Sáez-Cirión A, Hocqueloux L, Lascoux-Combe C, Allavena C, Goujard C, Valantin MA, Leplatois A, Meyer L, Rouzioux C, Autran B; OPTIPRIM ANRS-147 Study Group.

J Antimicrob Chemother. 2015 Jul;70(7):2108-20. doi: 10.1093/jac/dkv084. Epub 2015 Apr 21.


HIV Replication at Low Copy Number and its Correlation with the HIV Reservoir: A Clinical Perspective.

Sarmati L, D'Ettorre G, Parisi SG, Andreoni M.

Curr HIV Res. 2015;13(3):250-7.


Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration.

Thierry S, Munir S, Thierry E, Subra F, Leh H, Zamborlini A, Saenz D, Levy DN, Lesbats P, Saïb A, Parissi V, Poeschla E, Deprez E, Delelis O.

Retrovirology. 2015 Mar 12;12:24. doi: 10.1186/s12977-015-0153-9.


Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription.

Bermejo M, López-Huertas MR, Hedgpeth J, Mateos E, Rodríguez-Mora S, Maleno MJ, Plana M, Swindle J, Alcamí J, Coiras M.

Biochem Pharmacol. 2015 Apr 15;94(4):241-56. doi: 10.1016/j.bcp.2015.02.009. Epub 2015 Feb 27.


Broadly neutralizing antibody and the HIV reservoir in acute HIV infection: a strategy toward HIV remission?

Ananworanich J, McSteen B, Robb ML.

Curr Opin HIV AIDS. 2015 May;10(3):198-206. doi: 10.1097/COH.0000000000000144.


Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients.

Puertas MC, Salgado M, Morón-López S, Ouchi D, Muñoz-Moreno JA, Moltó J, Clotet B, Martinez-Picado J.

AIDS. 2014 Sep 10;28(14):2157-9. doi: 10.1097/QAD.0000000000000374.


Cross-clade ultrasensitive PCR-based assays to measure HIV persistence in large-cohort studies.

Vandergeeten C, Fromentin R, Merlini E, Lawani MB, DaFonseca S, Bakeman W, McNulty A, Ramgopal M, Michael N, Kim JH, Ananworanich J, Chomont N.

J Virol. 2014 Nov;88(21):12385-96. doi: 10.1128/JVI.00609-14. Epub 2014 Aug 13.


Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1.

Hill AL, Rosenbloom DI, Fu F, Nowak MA, Siliciano RF.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13475-80. doi: 10.1073/pnas.1406663111. Epub 2014 Aug 5. Erratum in: Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15598.


HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy.

Besson GJ, Lalama CM, Bosch RJ, Gandhi RT, Bedison MA, Aga E, Riddler SA, McMahon DK, Hong F, Mellors JW.

Clin Infect Dis. 2014 Nov 1;59(9):1312-21. doi: 10.1093/cid/ciu585. Epub 2014 Jul 29.


Improved virologic outcomes over time for HIV-infected patients on antiretroviral therapy in a cohort from Rio de Janeiro, 1997-2011.

Martin DA, Luz PM, Lake JE, Clark JL, Veloso VG, Moreira RI, Cardoso SW, Klausner JD, Grinsztejn B.

BMC Infect Dis. 2014 Jun 11;14:322. doi: 10.1186/1471-2334-14-322.


Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment.

Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM; California Collaborative Treatment Group 592 Team.

J Virol. 2014 Jul;88(14):7818-27. doi: 10.1128/JVI.00831-14. Epub 2014 Apr 30.


HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy.

Murray JM, Zaunders JJ, McBride KL, Xu Y, Bailey M, Suzuki K, Cooper DA, Emery S, Kelleher AD, Koelsch KK; PINT Study Team.

J Virol. 2014 Mar;88(6):3516-26. doi: 10.1128/JVI.03331-13. Epub 2014 Jan 8.


Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification.

Cardozo EF, Luo R, Piovoso MJ, Zurakowski R.

J Theor Biol. 2014 Mar 21;345:61-9. doi: 10.1016/j.jtbi.2013.12.020. Epub 2013 Dec 28.


Lymphoma and Epstein-Barr virus DNA in blood during interleukin-2 therapy in antiretroviral-naïve HIV-1-infected patients: a substudy of the ANRS 119 trial.

de Lastours V, LeGoff J, Brière J, Agbalika F, Boulet T, Lévy Y, Simon F, Aboulker JP, Molina JM.

HIV Med. 2014 Jan;15(1):23-9. doi: 10.1111/hiv.12077. Epub 2013 Sep 6.


Effect of antiretroviral therapy on HIV reservoirs in elite controllers.

Chun TW, Shawn Justement J, Murray D, Kim CJ, Blazkova J, Hallahan CW, Benko E, Costiniuk CT, Kandel G, Ostrowski M, Kaul R, Moir S, Casazza JP, Koup RA, Kovacs C, Fauci AS.

J Infect Dis. 2013 Nov 1;208(9):1443-7. doi: 10.1093/infdis/jit306. Epub 2013 Jul 11.


Lack of correlation between the size of HIV proviral DNA reservoir and the level of immune activation in HIV-infected patients with a sustained undetectable HIV viral load for 10 years.

Poizot-Martin I, Faucher O, Obry-Roguet V, Nicolino-Brunet C, Ronot-Bregigeon S, Dignat-George F, Tamalet C.

J Clin Virol. 2013 Aug;57(4):351-5. doi: 10.1016/j.jcv.2013.04.007. Epub 2013 May 8.

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