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Deficiency in the nuclear-related factor erythroid 2 transcription factor (Nrf1) leads to genetic instability.

Oh DH, Rigas D, Cho A, Chan JY.

FEBS J. 2012 Nov;279(22):4121-30. doi: 10.1111/febs.12005. Epub 2012 Oct 4.


Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

Leung L, Kwong M, Hou S, Lee C, Chan JY.

J Biol Chem. 2003 Nov 28;278(48):48021-9. Epub 2003 Sep 10.


The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells.

Engelbert D, Schnerch D, Baumgarten A, Wäsch R.

Oncogene. 2008 Feb 7;27(7):907-17. Epub 2007 Aug 13.


Nrf1 is critical for redox balance and survival of liver cells during development.

Chen L, Kwong M, Lu R, Ginzinger D, Lee C, Leung L, Chan JY.

Mol Cell Biol. 2003 Jul;23(13):4673-86.


NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes.

Hirotsu Y, Hataya N, Katsuoka F, Yamamoto M.

Mol Cell Biol. 2012 Jul;32(14):2760-70. doi: 10.1128/MCB.06706-11. Epub 2012 May 14.


Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes.

Zhao R, Hou Y, Zhang Q, Woods CG, Xue P, Fu J, Yarborough K, Guan D, Andersen ME, Pi J.

Environ Health Perspect. 2012 Apr;120(4):583-9. doi: 10.1289/ehp.1104580. Epub 2012 Jan 3.


RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation.

Amato A, Lentini L, Schillaci T, Iovino F, Di Leonardo A.

BMC Cell Biol. 2009 Nov 2;10:79. doi: 10.1186/1471-2121-10-79.


Expression of transcription factors during megakaryocytic differentiation of CD34+ cells from human cord blood induced by thrombopoietin.

Terui K, Takahashi Y, Kitazawa J, Toki T, Yokoyama M, Ito E.

Tohoku J Exp Med. 2000 Dec;192(4):259-73.


Effects of Kruppel-like factor 6 on osteosarcoma cell biological behavior.

Jianwei Z, Enzhong B, Fan L, Jian L, Ning A.

Tumour Biol. 2013 Apr;34(2):1097-105. doi: 10.1007/s13277-013-0651-0. Epub 2013 Jan 16.


Abnormal differentiation of erythroid precursors in p45 NF-E2(-/-) mice.

Gasiorek JJ, Nouhi Z, Blank V.

Exp Hematol. 2012 May;40(5):393-400. doi: 10.1016/j.exphem.2012.01.007. Epub 2012 Jan 17.


Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.

Xing W, Singgih A, Kapoor A, Alarcon CM, Baylink DJ, Mohan S.

J Biol Chem. 2007 Jul 27;282(30):22052-61. Epub 2007 May 17.


Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblasts.

Pratt CH, Curtain M, Donahue LR, Shopland LS.

PLoS One. 2011 Mar 25;6(3):e18065. doi: 10.1371/journal.pone.0018065.


Hydrogen peroxide-induced poly(ADP-ribosyl)ation regulates osteogenic differentiation-associated cell death.

Robaszkiewicz A, Erdélyi K, Kovács K, Kovács I, Bai P, Rajnavölgyi E, Virág L.

Free Radic Biol Med. 2012 Oct 15;53(8):1552-64. doi: 10.1016/j.freeradbiomed.2012.08.567. Epub 2012 Aug 20.


Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1.

Li M, Vascotto C, Xu S, Dai N, Qing Y, Zhong Z, Tell G, Wang D.

Free Radic Biol Med. 2012 Jul 15;53(2):237-48. doi: 10.1016/j.freeradbiomed.2012.04.002. Epub 2012 May 11.


Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C.

Kuzmanov A, Wielockx B, Rezaei M, Kettelhake A, Breier G.

Int J Cancer. 2012 Sep 1;131(5):E603-13. doi: 10.1002/ijc.27360. Epub 2012 Jan 3.


The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic β-cell proliferation and the expression of insulin regulators.

Shi K, Parekh VI, Roy S, Desai SS, Agarwal SK.

Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb.

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