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Results: 1 to 20 of 125

1.

Natural genetic variation in yeast longevity.

Stumpferl SW, Brand SE, Jiang JC, Korona B, Tiwari A, Dai J, Seo JG, Jazwinski SM.

Genome Res. 2012 Oct;22(10):1963-73. doi: 10.1101/gr.136549.111. Epub 2012 Sep 5.

PMID:
22955140
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.

Kwan EX, Foss EJ, Tsuchiyama S, Alvino GM, Kruglyak L, Kaeberlein M, Raghuraman MK, Brewer BJ, Kennedy BK, Bedalov A.

PLoS Genet. 2013;9(3):e1003329. doi: 10.1371/journal.pgen.1003329. Epub 2013 Mar 7.

PMID:
23505383
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SIR2 and other genes are abundantly expressed in long-lived natural segregants for replicative aging of the budding yeast Saccharomyces cerevisiae.

Guo Z, Adomas AB, Jackson ED, Qin H, Townsend JP.

FEMS Yeast Res. 2011 Jun;11(4):345-55. doi: 10.1111/j.1567-1364.2011.00723.x. Epub 2011 Mar 1.

PMID:
21306556
[PubMed - indexed for MEDLINE]
4.

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae.

Ha CW, Huh WK.

Aging (Albany NY). 2011 Mar;3(3):319-24. Review.

PMID:
21415463
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Calorie restriction effects on silencing and recombination at the yeast rDNA.

Smith DL Jr, Li C, Matecic M, Maqani N, Bryk M, Smith JS.

Aging Cell. 2009 Dec;8(6):633-42. doi: 10.1111/j.1474-9726.2009.00516.x. Epub 2009 Sep 2.

PMID:
19732044
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Yin and Yang of histone H2B roles in silencing and longevity: a tale of two arginines.

Dai J, Hyland EM, Norris A, Boeke JD.

Genetics. 2010 Nov;186(3):813-28. doi: 10.1534/genetics.110.118489. Epub 2010 Aug 16.

PMID:
20713692
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors.

Smith JS, Caputo E, Boeke JD.

Mol Cell Biol. 1999 Apr;19(4):3184-97.

PMID:
10082585
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Sir2 deletion prevents lifespan extension in 32 long-lived mutants.

Delaney JR, Sutphin GL, Dulken B, Sim S, Kim JR, Robison B, Schleit J, Murakami CJ, Carr D, An EH, Choi E, Chou A, Fletcher M, Jelic M, Liu B, Lockshon D, Moller RM, Pak DN, Peng Q, Peng ZJ, Pham KM, Sage M, Solanky A, Steffen KK, Tsuchiya M, Tsuchiyama S, Johnson S, Raabe C, Suh Y, Zhou Z, Liu X, Kennedy BK, Kaeberlein M.

Aging Cell. 2011 Dec;10(6):1089-91. doi: 10.1111/j.1474-9726.2011.00742.x. Epub 2011 Oct 3.

PMID:
21902802
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae.

Kim S, Benguria A, Lai CY, Jazwinski SM.

Mol Biol Cell. 1999 Oct;10(10):3125-36.

PMID:
10512855
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.

McClure JM, Wierman MB, Maqani N, Smith JS.

J Biol Chem. 2012 Jun 15;287(25):20957-66. doi: 10.1074/jbc.M112.367524. Epub 2012 Apr 26.

PMID:
22539348
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast.

Kobayashi T, Horiuchi T, Tongaonkar P, Vu L, Nomura M.

Cell. 2004 May 14;117(4):441-53.

PMID:
15137938
[PubMed - indexed for MEDLINE]
12.

QTL analysis of high thermotolerance with superior and downgraded parental yeast strains reveals new minor QTLs and converges on novel causative alleles involved in RNA processing.

Yang Y, Foulquié-Moreno MR, Clement L, Erdei E, Tanghe A, Schaerlaekens K, Dumortier F, Thevelein JM.

PLoS Genet. 2013;9(8):e1003693. doi: 10.1371/journal.pgen.1003693. Epub 2013 Aug 15.

PMID:
23966873
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Calorie restriction reduces rDNA recombination independently of rDNA silencing.

Riesen M, Morgan A.

Aging Cell. 2009 Dec;8(6):624-32. doi: 10.1111/j.1474-9726.2009.00514.x. Epub 2009 Sep 2.

PMID:
19732046
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae.

Ha CW, Sung MK, Huh WK.

Nucleic Acids Res. 2012 Jun;40(11):4892-903. doi: 10.1093/nar/gks188. Epub 2012 Feb 22.

PMID:
22362748
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Perinuclear cohibin complexes maintain replicative life span via roles at distinct silent chromatin domains.

Chan JN, Poon BP, Salvi J, Olsen JB, Emili A, Mekhail K.

Dev Cell. 2011 Jun 14;20(6):867-79. doi: 10.1016/j.devcel.2011.05.014.

PMID:
21664583
[PubMed - indexed for MEDLINE]
Free Article
16.

An unusual form of transcriptional silencing in yeast ribosomal DNA.

Smith JS, Boeke JD.

Genes Dev. 1997 Jan 15;11(2):241-54.

PMID:
9009206
[PubMed - indexed for MEDLINE]
Free Article
17.

Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.

Fritze CE, Verschueren K, Strich R, Easton Esposito R.

EMBO J. 1997 Nov 3;16(21):6495-509.

PMID:
9351831
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis.

Swinnen S, Schaerlaekens K, Pais T, Claesen J, Hubmann G, Yang Y, Demeke M, Foulquié-Moreno MR, Goovaerts A, Souvereyns K, Clement L, Dumortier F, Thevelein JM.

Genome Res. 2012 May;22(5):975-84. doi: 10.1101/gr.131698.111. Epub 2012 Mar 7.

PMID:
22399573
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast.

Sinha H, David L, Pascon RC, Clauder-Münster S, Krishnakumar S, Nguyen M, Shi G, Dean J, Davis RW, Oefner PJ, McCusker JH, Steinmetz LM.

Genetics. 2008 Nov;180(3):1661-70. doi: 10.1534/genetics.108.092932. Epub 2008 Sep 9.

PMID:
18780730
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p.

Smith JS, Brachmann CB, Pillus L, Boeke JD.

Genetics. 1998 Jul;149(3):1205-19.

PMID:
9649515
[PubMed - indexed for MEDLINE]
Free PMC Article

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