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Items: 1 to 20 of 117


Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.

Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K.

BMC Genomics. 2012 Aug 20;13:411. doi: 10.1186/1471-2164-13-411.


Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.

Boon AC, deBeauchamp J, Hollmann A, Luke J, Kotb M, Rowe S, Finkelstein D, Neale G, Lu L, Williams RW, Webby RJ.

J Virol. 2009 Oct;83(20):10417-26. doi: 10.1128/JVI.00514-09. Epub 2009 Aug 12.


Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection.

Bahgat MM, Błazejewska P, Schughart K.

Virol J. 2011 Jan 20;8:27. doi: 10.1186/1743-422X-8-27.


Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.

Shin DL, Hatesuer B, Bergmann S, Nedelko T, Schughart K.

J Virol. 2015 Oct;89(19):9998-10009. doi: 10.1128/JVI.01305-15. Epub 2015 Jul 22.


RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection.

Wilk E, Pandey AK, Leist SR, Hatesuer B, Preusse M, Pommerenke C, Wang J, Schughart K.

BMC Genomics. 2015 Sep 2;16:655. doi: 10.1186/s12864-015-1867-8.


Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection.

Alberts R, Srivastava B, Wu H, Viegas N, Geffers R, Klawonn F, Novoselova N, do Valle TZ, Panthier JJ, Schughart K.

Microbes Infect. 2010 Apr;12(4):309-18. doi: 10.1016/j.micinf.2010.01.008. Epub 2010 Jan 28.


Host genetic background strongly influences the response to influenza a virus infections.

Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD, Schughart K.

PLoS One. 2009;4(3):e4857. doi: 10.1371/journal.pone.0004857. Epub 2009 Mar 18.


Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice.

Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F.

BMC Microbiol. 2013 Dec 17;13:293. doi: 10.1186/1471-2180-13-293.


Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains.

Preusse M, Schughart K, Wilk E, Klawonn F, Pessler F.

BMC Res Notes. 2015 Jun 6;8:225. doi: 10.1186/s13104-015-1195-8.


A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice.

Boon AC, Williams RW, Sinasac DS, Webby RJ.

BMC Genomics. 2014 Nov 24;15:1017. doi: 10.1186/1471-2164-15-1017.


Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.

Dengler L, May M, Wilk E, Bahgat MM, Schughart K.

Virol J. 2012 Sep 19;9:212. doi: 10.1186/1743-422X-9-212.


A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice.

Thompson RL, Williams RW, Kotb M, Sawtell NM.

PLoS One. 2014 Mar 20;9(3):e92342. doi: 10.1371/journal.pone.0092342. eCollection 2014.


Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice.

Yadav JS, Pradhan S, Kapoor R, Bangar H, Burzynski BB, Prows DR, Levin L.

Infect Immun. 2011 Aug;79(8):3204-15. doi: 10.1128/IAI.01389-10. Epub 2011 May 31.


2009 pandemic H1N1 influenza A virus strains display differential pathogenicity in C57BL/6J but not BALB/c mice.

Otte A, Gabriel G.

Virulence. 2011 Nov-Dec;2(6):563-6. doi: 10.4161/viru.2.6.18148. Epub 2011 Nov 1.


Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT.

PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28.


Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight.

Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC.

BMC Genomics. 2008 Sep 25;9:444. doi: 10.1186/1471-2164-9-444.


Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68.

Boivin GA, Pothlichet J, Skamene E, Brown EG, Loredo-Osti JC, Sladek R, Vidal SM.

J Immunol. 2012 Apr 15;188(8):3949-60. doi: 10.4049/jimmunol.1103320. Epub 2012 Mar 16.


MicroRNA expression profile of mouse lung infected with 2009 pandemic H1N1 influenza virus.

Wu Z, Hao R, Li P, Zhang X, Liu N, Qiu S, Wang L, Wang Y, Xue W, Liu K, Yang G, Cui J, Zhang C, Song H.

PLoS One. 2013 Sep 16;8(9):e74190. doi: 10.1371/journal.pone.0074190. eCollection 2013.


Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.

Mitsos LM, Cardon LR, Fortin A, Ryan L, LaCourse R, North RJ, Gros P.

Genes Immun. 2000 Dec;1(8):467-77.


Quantitative genetics of age-related retinal degeneration: a second F1 intercross between the A/J and C57BL/6 strains.

Danciger M, Yang H, Ralston R, Liu Y, Matthes MT, Peirce J, Lavail MM.

Mol Vis. 2007 Jan 25;13:79-85.

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