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Results: 1 to 20 of 96

1.

Cancer vulnerabilities unveiled by genomic loss.

Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC.

Cell. 2012 Aug 17;150(4):842-54. doi: 10.1016/j.cell.2012.07.023.

PMID:
22901813
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.

Lassmann S, Weis R, Makowiec F, Roth J, Danciu M, Hopt U, Werner M.

J Mol Med (Berl). 2007 Mar;85(3):293-304. Epub 2006 Dec 2.

PMID:
17143621
[PubMed - indexed for MEDLINE]
3.

Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines.

Hermans KG, van Alewijk DC, Veltman JA, van Weerden W, van Kessel AG, Trapman J.

Genes Chromosomes Cancer. 2004 Mar;39(3):171-84.

PMID:
14732919
[PubMed - indexed for MEDLINE]
4.

Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes.

Kok K, Naylor SL, Buys CH.

Adv Cancer Res. 1997;71:27-92. Review.

PMID:
9111863
[PubMed - indexed for MEDLINE]
5.

Passenger deletions generate therapeutic vulnerabilities in cancer.

Muller FL, Colla S, Aquilanti E, Manzo VE, Genovese G, Lee J, Eisenson D, Narurkar R, Deng P, Nezi L, Lee MA, Hu B, Hu J, Sahin E, Ong D, Fletcher-Sananikone E, Ho D, Kwong L, Brennan C, Wang YA, Chin L, DePinho RA.

Nature. 2012 Aug 16;488(7411):337-42. doi: 10.1038/nature11331.

PMID:
22895339
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.

Lee GY, Haverty PM, Li L, Kljavin NM, Bourgon R, Lee J, Stern H, Modrusan Z, Seshagiri S, Zhang Z, Davis D, Stokoe D, Settleman J, de Sauvage FJ, Neve RM.

Cancer Res. 2014 Jun 1;74(11):3114-26. doi: 10.1158/0008-5472.CAN-13-2683. Epub 2014 Apr 22.

PMID:
24755469
[PubMed - indexed for MEDLINE]
7.

Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast.

Hawthorn L, Luce J, Stein L, Rothschild J.

BMC Cancer. 2010 Aug 27;10:460. doi: 10.1186/1471-2407-10-460.

PMID:
20799942
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL.

Bartos JD, Gaile DP, McQuaid DE, Conroy JM, Darbary H, Nowak NJ, Block A, Petrelli NJ, Mittelman A, Stoler DL, Anderson GR.

Mutat Res. 2007 Feb 3;615(1-2):1-11. Epub 2007 Jan 2.

PMID:
17196995
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data.

Ɓastowska M, Viprey V, Santibanez-Koref M, Wappler I, Peters H, Cullinane C, Roberts P, Hall AG, Tweddle DA, Pearson AD, Lewis I, Burchill SA, Jackson MS.

Oncogene. 2007 Nov 22;26(53):7432-44. Epub 2007 May 28.

PMID:
17533364
[PubMed - indexed for MEDLINE]
10.

Comprehensive copy number profiles of breast cancer cell model genomes.

Shadeo A, Lam WL.

Breast Cancer Res. 2006;8(1):R9. Epub 2006 Jan 3.

PMID:
16417655
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis.

Yamanaka S, Sunamura M, Furukawa T, Sun L, Lefter LP, Abe T, Yatsuoka T, Fujimura H, Shibuya E, Kotobuki N, Oshimura M, Sakurada A, Sato M, Kondo T, Matsuno S, Horii A.

Lab Invest. 2004 Oct;84(10):1339-51.

PMID:
15300227
[PubMed - indexed for MEDLINE]
Free Article
12.

Breast tumor copy number aberration phenotypes and genomic instability.

Fridlyand J, Snijders AM, Ylstra B, Li H, Olshen A, Segraves R, Dairkee S, Tokuyasu T, Ljung BM, Jain AN, McLennan J, Ziegler J, Chin K, Devries S, Feiler H, Gray JW, Waldman F, Pinkel D, Albertson DG.

BMC Cancer. 2006 Apr 18;6:96.

PMID:
16620391
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The PMAIP1 gene on chromosome 18 is a candidate tumor suppressor gene in human pancreatic cancer.

Ishida M, Sunamura M, Furukawa T, Lefter LP, Morita R, Akada M, Egawa S, Unno M, Horii A.

Dig Dis Sci. 2008 Sep;53(9):2576-82. doi: 10.1007/s10620-007-0154-1. Epub 2008 Jan 31.

PMID:
18231856
[PubMed - indexed for MEDLINE]
14.

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer.

Kloth JN, Oosting J, van Wezel T, Szuhai K, Knijnenburg J, Gorter A, Kenter GG, Fleuren GJ, Jordanova ES.

BMC Genomics. 2007 Feb 20;8:53.

PMID:
17311676
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular profiling of patient-derived breast cancer xenografts.

Reyal F, Guyader C, Decraene C, Lucchesi C, Auger N, Assayag F, De Plater L, Gentien D, Poupon MF, Cottu P, De Cremoux P, Gestraud P, Vincent-Salomon A, Fontaine JJ, Roman-Roman S, Delattre O, Decaudin D, Marangoni E.

Breast Cancer Res. 2012 Jan 16;14(1):R11.

PMID:
22247967
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Involvement of the multiple tumor suppressor genes and 12-lipoxygenase in human prostate cancer. Therapeutic implications.

Gao X, Porter AT, Honn KV.

Adv Exp Med Biol. 1997;407:41-53. Review.

PMID:
9321930
[PubMed - indexed for MEDLINE]
17.

1p36 tumor suppression--a matter of dosage?

Henrich KO, Schwab M, Westermann F.

Cancer Res. 2012 Dec 1;72(23):6079-88. doi: 10.1158/0008-5472.CAN-12-2230. Epub 2012 Nov 20. Review.

PMID:
23172308
[PubMed - indexed for MEDLINE]
Free Article
18.

Genome-wide gene copy number and expression analysis of primary gastric tumors and gastric cancer cell lines.

Junnila S, Kokkola A, Karjalainen-Lindsberg ML, Puolakkainen P, Monni O.

BMC Cancer. 2010 Mar 1;10:73. doi: 10.1186/1471-2407-10-73.

PMID:
20187983
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.

Cell. 2009 May 29;137(5):835-48. doi: 10.1016/j.cell.2009.05.006.

PMID:
19490893
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer.

Fan B, Dachrut S, Coral H, Yuen ST, Chu KM, Law S, Zhang L, Ji J, Leung SY, Chen X.

PLoS One. 2012;7(4):e29824. doi: 10.1371/journal.pone.0029824. Epub 2012 Apr 23.

PMID:
22539939
[PubMed - indexed for MEDLINE]
Free PMC Article

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