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Results: 1 to 20 of 94

1.

Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.

Wallace MD, Pfefferle AD, Shen L, McNairn AJ, Cerami EG, Fallon BL, Rinaldi VD, Southard TL, Perou CM, Schimenti JC.

Genetics. 2012 Oct;192(2):385-96. doi: 10.1534/genetics.112.142802. Epub 2012 Jul 30.

PMID:
22851646
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.

Herschkowitz JI, Zhao W, Zhang M, Usary J, Murrow G, Edwards D, Knezevic J, Greene SB, Darr D, Troester MA, Hilsenbeck SG, Medina D, Perou CM, Rosen JM.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2778-83. doi: 10.1073/pnas.1018862108. Epub 2011 Jun 1.

PMID:
21633010
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.

Holstege H, van Beers E, Velds A, Liu X, Joosse SA, Klarenbeek S, Schut E, Kerkhoven R, Klijn CN, Wessels LF, Nederlof PM, Jonkers J.

BMC Cancer. 2010 Aug 24;10:455. doi: 10.1186/1471-2407-10-455.

PMID:
20735817
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.

Sangha N, Wu R, Kuick R, Powers S, Mu D, Fiander D, Yuen K, Katabuchi H, Tashiro H, Fearon ER, Cho KR.

Neoplasia. 2008 Dec;10(12):1362-72, following 1372.

PMID:
19048115
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways.

Shapira S, Barkan B, Friedman E, Kloog Y, Stein R.

Cell Death Differ. 2007 May;14(5):895-906. Epub 2006 Nov 10. Erratum in: Cell Death Differ. 2007 May;14(5):1070. Fridman, E [corrected to Friedman, E].

PMID:
17096025
[PubMed - indexed for MEDLINE]
Free Article
7.

Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells.

Li F, Munchhof AM, White HA, Mead LE, Krier TR, Fenoglio A, Chen S, Wu X, Cai S, Yang FC, Ingram DA.

Hum Mol Genet. 2006 Jun 1;15(11):1921-30. Epub 2006 Apr 27.

PMID:
16644864
[PubMed - indexed for MEDLINE]
Free Article
8.

Metastatic canine mammary carcinomas can be identified by a gene expression profile that partly overlaps with human breast cancer profiles.

Klopfleisch R, Lenze D, Hummel M, Gruber AD.

BMC Cancer. 2010 Nov 9;10:618. doi: 10.1186/1471-2407-10-618.

PMID:
21062462
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Comparative epigenomics of human and mouse mammary tumors.

Demircan B, Dyer LM, Gerace M, Lobenhofer EK, Robertson KD, Brown KD.

Genes Chromosomes Cancer. 2009 Jan;48(1):83-97. doi: 10.1002/gcc.20620.

PMID:
18836996
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer.

Staaf J, Jönsson G, Ringnér M, Baldetorp B, Borg A.

Breast Cancer Res. 2011;13(6):R129. doi: 10.1186/bcr3075. Epub 2011 Dec 14.

PMID:
22169037
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Comparative expression pathway analysis of human and canine mammary tumors.

Uva P, Aurisicchio L, Watters J, Loboda A, Kulkarni A, Castle J, Palombo F, Viti V, Mesiti G, Zappulli V, Marconato L, Abramo F, Ciliberto G, Lahm A, La Monica N, de Rinaldis E.

BMC Genomics. 2009 Mar 27;10:135. doi: 10.1186/1471-2164-10-135.

PMID:
19327144
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

High-resolution genomic and expression analyses of copy number alterations in breast tumors.

Haverty PM, Fridlyand J, Li L, Getz G, Beroukhim R, Lohr S, Wu TD, Cavet G, Zhang Z, Chant J.

Genes Chromosomes Cancer. 2008 Jun;47(6):530-42. doi: 10.1002/gcc.20558.

PMID:
18335499
[PubMed - indexed for MEDLINE]
13.

NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.

Xu J, Ismat FA, Wang T, Yang J, Epstein JA.

Circulation. 2007 Nov 6;116(19):2148-56. Epub 2007 Oct 22.

PMID:
17967772
[PubMed - indexed for MEDLINE]
Free Article
14.

Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis.

McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, Scheffzek K, Stemmer-Rachamimov AO, Sawyers CL, Brennan C, Messiaen L, Mellinghoff IK, Cichowski K.

Cancer Cell. 2009 Jul 7;16(1):44-54. doi: 10.1016/j.ccr.2009.05.009.

PMID:
19573811
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Identifying the Ubiquitin Ligase complex that regulates the NF1 tumor suppressor and Ras.

Hollstein PE, Cichowski K.

Cancer Discov. 2013 Aug;3(8):880-93. doi: 10.1158/2159-8290.CD-13-0146. Epub 2013 May 9.

PMID:
23661552
[PubMed - indexed for MEDLINE]
16.

The neurofibromin 1 type I isoform predominance characterises female population affected by sporadic breast cancer: preliminary data.

Marrero D, Peralta R, Valdivia A, De la Mora A, Romero P, Parra M, Mendoza N, Mendoza M, Rodriguez D, Camacho E, Duarte A, Castelazo G, Vanegas E, Garcia I, Vargas C, Arenas D, Jimenez F, Salcedo M.

J Clin Pathol. 2012 May;65(5):419-23. doi: 10.1136/jclinpath-2011-200569. Epub 2012 Mar 12.

PMID:
22412049
[PubMed - indexed for MEDLINE]
17.

Genome-wide copy number alterations in subtypes of invasive breast cancers in young white and African American women.

Loo LW, Wang Y, Flynn EM, Lund MJ, Bowles EJ, Buist DS, Liff JM, Flagg EW, Coates RJ, Eley JW, Hsu L, Porter PL.

Breast Cancer Res Treat. 2011 May;127(1):297-308. doi: 10.1007/s10549-010-1297-x. Epub 2011 Jan 25.

PMID:
21264507
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer.

Chan MM, Lu X, Merchant FM, Iglehart JD, Miron PL.

Carcinogenesis. 2005 Aug;26(8):1343-53. Epub 2005 Apr 21.

PMID:
15845649
[PubMed - indexed for MEDLINE]
Free Article
19.

Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor.

Cichowski K, Santiago S, Jardim M, Johnson BW, Jacks T.

Genes Dev. 2003 Feb 15;17(4):449-54.

PMID:
12600938
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.

Su W, Xing R, Guha A, Gutmann DH, Sherman LS.

Glia. 2007 May;55(7):723-33.

PMID:
17348023
[PubMed - indexed for MEDLINE]

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