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Related Citations for PubMed (Select 22814605)


Separase biosensor reveals that cohesin cleavage timing depends on phosphatase PP2A(Cdc55) regulation.

Yaakov G, Thorn K, Morgan DO.

Dev Cell. 2012 Jul 17;23(1):124-36. doi: 10.1016/j.devcel.2012.06.007.


Shugoshin prevents cohesin cleavage by PP2A(Cdc55)-dependent inhibition of separase.

Clift D, Bizzari F, Marston AL.

Genes Dev. 2009 Mar 15;23(6):766-80. doi: 10.1101/gad.507509.


Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis.

Katis VL, Lipp JJ, Imre R, Bogdanova A, Okaz E, Habermann B, Mechtler K, Nasmyth K, Zachariae W.

Dev Cell. 2010 Mar 16;18(3):397-409. doi: 10.1016/j.devcel.2010.01.014.


Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.

Hauf S, Waizenegger IC, Peters JM.

Science. 2001 Aug 17;293(5533):1320-3.


Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin.

McAleenan A, Clemente-Blanco A, Cordon-Preciado V, Sen N, Esteras M, Jarmuz A, Aragón L.

Nature. 2013 Jan 10;493(7431):250-4. doi: 10.1038/nature11630. Epub 2012 Nov 25.


The protease activity of yeast separase (esp1) is required for anaphase spindle elongation independently of its role in cleavage of cohesin.

Baskerville C, Segal M, Reed SI.

Genetics. 2008 Apr;178(4):2361-72. doi: 10.1534/genetics.107.085308.


The complete removal of cohesin from chromosome arms depends on separase.

Nakajima M, Kumada K, Hatakeyama K, Noda T, Peters JM, Hirota T.

J Cell Sci. 2007 Dec 1;120(Pt 23):4188-96. Epub 2007 Nov 14.


Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A.

Tang X, Wang Y.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16290-5. Epub 2006 Oct 18.


Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.

Hauf S, Roitinger E, Koch B, Dittrich CM, Mechtler K, Peters JM.

PLoS Biol. 2005 Mar;3(3):e69. Epub 2005 Mar 1.


DNA-dependent cohesin cleavage by separase.

Kucej M, Zou H.

Nucleus. 2010 Jan-Feb;1(1):4-7. doi: 10.4161/nucl.1.1.10010.


Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase.

Queralt E, Uhlmann F.

J Cell Biol. 2008 Sep 8;182(5):873-83. doi: 10.1083/jcb.200801054. Epub 2008 Sep 1.


Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast.

Alexandru G, Uhlmann F, Mechtler K, Poupart MA, Nasmyth K.

Cell. 2001 May 18;105(4):459-72.


[Activity of separase and its regulation].

Xie XY, Pu XY.

Yi Chuan. 2004 May;26(3):383-6. Review. Chinese.


Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19.

Sullivan M, Lehane C, Uhlmann F.

Nat Cell Biol. 2001 Sep;3(9):771-7.


Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast.

Queralt E, Lehane C, Novak B, Uhlmann F.

Cell. 2006 May 19;125(4):719-32.


Separase sensor reveals dual roles for separase coordinating cohesin cleavage and cdk1 inhibition.

Shindo N, Kumada K, Hirota T.

Dev Cell. 2012 Jul 17;23(1):112-23. doi: 10.1016/j.devcel.2012.06.015.


The budding yeast PP2ACdc55 protein phosphatase prevents the onset of anaphase in response to morphogenetic defects.

Chiroli E, Rossio V, Lucchini G, Piatti S.

J Cell Biol. 2007 May 21;177(4):599-611. Epub 2007 May 14.


Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

Riedel CG, Katis VL, Katou Y, Mori S, Itoh T, Helmhart W, Gálová M, Petronczki M, Gregan J, Cetin B, Mudrak I, Ogris E, Mechtler K, Pelletier L, Buchholz F, Shirahige K, Nasmyth K.

Nature. 2006 May 4;441(7089):53-61. Epub 2006 Mar 15.


Structure and function of the PP2A-shugoshin interaction.

Xu Z, Cetin B, Anger M, Cho US, Helmhart W, Nasmyth K, Xu W.

Mol Cell. 2009 Aug 28;35(4):426-41. doi: 10.1016/j.molcel.2009.06.031.

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