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Results: 1 to 20 of 103

1.

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

Fusco C, Micale L, Egorov M, Monti M, D'Addetta EV, Augello B, Cozzolino F, Calcagnì A, Fontana A, Polishchuk RS, Didelot G, Reymond A, Pucci P, Merla G.

PLoS One. 2012;7(7):e40440. doi: 10.1371/journal.pone.0040440. Epub 2012 Jul 9.

PMID:
22792322
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

Yan J, Seibenhener ML, Calderilla-Barbosa L, Diaz-Meco MT, Moscat J, Jiang J, Wooten MW, Wooten MC.

PLoS One. 2013 Sep 27;8(9):e76016. doi: 10.1371/journal.pone.0076016. eCollection 2013.

PMID:
24086678
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains.

Hao R, Nanduri P, Rao Y, Panichelli RS, Ito A, Yoshida M, Yao TP.

Mol Cell. 2013 Sep 26;51(6):819-28. doi: 10.1016/j.molcel.2013.08.016. Epub 2013 Sep 12.

PMID:
24035499
[PubMed - indexed for MEDLINE]
4.

HDAC6 mediates the acetylation of TRIM50.

Fusco C, Micale L, Augello B, Mandriani B, Pellico MT, De Nittis P, Calcagnì A, Monti M, Cozzolino F, Pucci P, Merla G.

Cell Signal. 2014 Feb;26(2):363-9. doi: 10.1016/j.cellsig.2013.11.036. Epub 2013 Dec 2.

PMID:
24308962
[PubMed - in process]
5.

A critical role for CHIP in the aggresome pathway.

Sha Y, Pandit L, Zeng S, Eissa NT.

Mol Cell Biol. 2009 Jan;29(1):116-28. doi: 10.1128/MCB.00829-08. Epub 2008 Oct 27.

PMID:
18955503
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

Ouyang H, Ali YO, Ravichandran M, Dong A, Qiu W, MacKenzie F, Dhe-Paganon S, Arrowsmith CH, Zhai RG.

J Biol Chem. 2012 Jan 20;287(4):2317-27. doi: 10.1074/jbc.M111.273730. Epub 2011 Nov 8.

PMID:
22069321
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate.

Watanabe Y, Tanaka M.

J Cell Sci. 2011 Aug 15;124(Pt 16):2692-701. doi: 10.1242/jcs.081232. Epub 2011 Jul 19.

PMID:
21771882
[PubMed - indexed for MEDLINE]
Free Article
8.

Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome.

Jiang Q, Ren Y, Feng J.

J Neurosci. 2008 Nov 26;28(48):12993-3002. doi: 10.1523/JNEUROSCI.2860-08.2008.

PMID:
19036992
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.

Carew JS, Medina EC, Esquivel JA 2nd, Mahalingam D, Swords R, Kelly K, Zhang H, Huang P, Mita AC, Mita MM, Giles FJ, Nawrocki ST.

J Cell Mol Med. 2010 Oct;14(10):2448-59. doi: 10.1111/j.1582-4934.2009.00832.x.

PMID:
19583815
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition.

Kalveram B, Schmidtke G, Groettrup M.

J Cell Sci. 2008 Dec 15;121(Pt 24):4079-88. doi: 10.1242/jcs.035006. Epub 2008 Nov 25.

PMID:
19033385
[PubMed - indexed for MEDLINE]
Free Article
11.

Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).

Hebron ML, Lonskaya I, Sharpe K, Weerasinghe PP, Algarzae NK, Shekoyan AR, Moussa CE.

J Biol Chem. 2013 Feb 8;288(6):4103-15. doi: 10.1074/jbc.M112.419945. Epub 2012 Dec 20.

PMID:
23258539
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration.

Richter-Landsberg C, Leyk J.

Acta Neuropathol. 2013 Dec;126(6):793-807. doi: 10.1007/s00401-013-1158-x. Epub 2013 Aug 3. Review.

PMID:
23912309
[PubMed - indexed for MEDLINE]
13.

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy.

Lee JY, Nagano Y, Taylor JP, Lim KL, Yao TP.

J Cell Biol. 2010 May 17;189(4):671-9. doi: 10.1083/jcb.201001039. Epub 2010 May 10.

PMID:
20457763
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.

Myeku N, Figueiredo-Pereira ME.

J Biol Chem. 2011 Jun 24;286(25):22426-40. doi: 10.1074/jbc.M110.149252. Epub 2011 May 2.

PMID:
21536669
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Selective autophagy: ubiquitin-mediated recognition and beyond.

Kraft C, Peter M, Hofmann K.

Nat Cell Biol. 2010 Sep;12(9):836-41. doi: 10.1038/ncb0910-836.

PMID:
20811356
[PubMed - indexed for MEDLINE]
16.

The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression.

Benavides M, Chow-Tsang LF, Zhang J, Zhong H.

Biochim Biophys Acta. 2013 Jan;1833(1):21-32. doi: 10.1016/j.bbamcr.2012.10.007. Epub 2012 Oct 12.

PMID:
23069210
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N.

Mol Cell. 2011 Oct 21;44(2):279-89. doi: 10.1016/j.molcel.2011.07.039.

PMID:
22017874
[PubMed - indexed for MEDLINE]
Free Article
18.

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.

Chin LS, Olzmann JA, Li L.

Biochem Soc Trans. 2010 Feb;38(Pt 1):144-9. doi: 10.1042/BST0380144. Review.

PMID:
20074049
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Fighting disease by selective autophagy of aggregate-prone proteins.

Knaevelsrud H, Simonsen A.

FEBS Lett. 2010 Jun 18;584(12):2635-45. doi: 10.1016/j.febslet.2010.04.041. Epub 2010 Apr 20. Review.

PMID:
20412801
[PubMed - indexed for MEDLINE]
Free Article
20.

Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.

Olzmann JA, Chin LS.

Autophagy. 2008 Jan;4(1):85-7. Epub 2007 Oct 15.

PMID:
17957134
[PubMed - indexed for MEDLINE]
Free PMC Article

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