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Related Citations for PubMed (Select 22786724)


Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase.

Kim HS, Das A, Gross CC, Bryceson YT, Long EO.

Immunity. 2010 Feb 26;32(2):175-86. doi: 10.1016/j.immuni.2010.02.004.


Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.

Sylvain NR, Nguyen K, Bunnell SC.

Sci Signal. 2011 Mar 8;4(163):ra14. doi: 10.1126/scisignal.2001178.


Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function.

May RM, Okumura M, Hsu CJ, Bassiri H, Yang E, Rak G, Mace EM, Philip NH, Zhang W, Baumgart T, Orange JS, Nichols KE, Kambayashi T.

Blood. 2013 Apr 18;121(16):3135-46. doi: 10.1182/blood-2012-12-474361. Epub 2013 Feb 13.


Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET.

Pauker MH, Hassan N, Noy E, Reicher B, Barda-Saad M.

Sci Signal. 2012 Apr 24;5(221):rs3. doi: 10.1126/scisignal.2002423.


Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

Eissmann P, Beauchamp L, Wooters J, Tilton JC, Long EO, Watzl C.

Blood. 2005 Jun 15;105(12):4722-9. Epub 2005 Feb 15.


Natural killer cell signaling pathways.

Vivier E, Nunès JA, Vély F.

Science. 2004 Nov 26;306(5701):1517-9.


A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, Ozaki Y, Watson SP.

Blood. 2006 Jan 15;107(2):542-9. Epub 2005 Sep 20.


The adaptor protein 3BP2 binds human CD244 and links this receptor to Vav signaling, ERK activation, and NK cell killing.

Saborit-Villarroya I, Del Valle JM, Romero X, Esplugues E, Lauzurica P, Engel P, Martín M.

J Immunol. 2005 Oct 1;175(7):4226-35.


SLP-76-Cbl-Grb2-Shc interactions in FcgammaRI signaling.

Chu J, Liu Y, Koretzky GA, Durden DL.

Blood. 1998 Sep 1;92(5):1697-706.


Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages.

Erdreich-Epstein A, Liu M, Kant AM, Izadi KD, Nolta JA, Durden DL.

J Leukoc Biol. 1999 Apr;65(4):523-34.


Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.

Hussain A, Mohammad DK, Gustafsson MO, Uslu M, Hamasy A, Nore BF, Mohamed AJ, Smith CI.

J Biol Chem. 2013 Mar 8;288(10):7338-50. doi: 10.1074/jbc.M112.374967. Epub 2013 Jan 4.


UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.

Sutherland CL, Chalupny NJ, Schooley K, VandenBos T, Kubin M, Cosman D.

J Immunol. 2002 Jan 15;168(2):671-9.


Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors.

Chen R, Relouzat F, Roncagalli R, Aoukaty A, Tan R, Latour S, Veillette A.

Mol Cell Biol. 2004 Jun;24(12):5144-56.


Vav1-phospholipase C-γ1 (Vav1-PLC-γ1) pathway initiated by T cell antigen receptor (TCRγδ) activation is required to overcome inhibition by ubiquitin ligase Cbl-b during γδT cell cytotoxicity.

Yin S, Zhang J, Mao Y, Hu Y, Cui L, Kang N, He W.

J Biol Chem. 2013 Sep 13;288(37):26448-62. doi: 10.1074/jbc.M113.484600. Epub 2013 Jul 29.


SLP-76 is recruited to CD22 and dephosphorylated by SHP-1, thereby regulating B cell receptor-induced c-Jun N-terminal kinase activation.

Mizuno K, Tagawa Y, Watanabe N, Ogimoto M, Yakura H.

Eur J Immunol. 2005 Feb;35(2):644-54.


NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.

Upshaw JL, Arneson LN, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ.

Nat Immunol. 2006 May;7(5):524-32. Epub 2006 Apr 2.


Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells.

Mesecke S, Urlaub D, Busch H, Eils R, Watzl C.

Sci Signal. 2011 May 31;4(175):ra36. doi: 10.1126/scisignal.2001325.

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