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Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation.

Zheng D, Giljohann DA, Chen DL, Massich MD, Wang XQ, Iordanov H, Mirkin CA, Paller AS.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11975-80. doi: 10.1073/pnas.1118425109. Epub 2012 Jul 6.


siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown.

Randeria PS, Seeger MA, Wang XQ, Wilson H, Shipp D, Mirkin CA, Paller AS.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5573-8. doi: 10.1073/pnas.1505951112. Epub 2015 Apr 20.


Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice.

Xian W, Kiguchi K, Imamoto A, Rupp T, Zilberstein A, DiGiovanni J.

Cell Growth Differ. 1995 Nov;6(11):1447-55.


Development of an efficient transdermal delivery system of small interfering RNA using functional peptides, Tat and AT-1002.

Uchida T, Kanazawa T, Takashima Y, Okada H.

Chem Pharm Bull (Tokyo). 2011;59(2):196-201.


Chemosensitization of cancer cells by siRNA using targeted nanogel delivery.

Dickerson EB, Blackburn WH, Smith MH, Kapa LB, Lyon LA, McDonald JF.

BMC Cancer. 2010 Jan 11;10:10. doi: 10.1186/1471-2407-10-10.


Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.

Franzke CW, Cobzaru C, Triantafyllopoulou A, Löffek S, Horiuchi K, Threadgill DW, Kurz T, van Rooijen N, Bruckner-Tuderman L, Blobel CP.

J Exp Med. 2012 Jun 4;209(6):1105-19. doi: 10.1084/jem.20112258. Epub 2012 May 7. Erratum in: J Exp Med. 2012 Dec 17;209(13):2517.


Topical delivery of siRNA into skin using SPACE-peptide carriers.

Chen M, Zakrewsky M, Gupta V, Anselmo AC, Slee DH, Muraski JA, Mitragotri S.

J Control Release. 2014 Apr 10;179:33-41. doi: 10.1016/j.jconrel.2014.01.006. Epub 2014 Jan 13.


Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function.

Xu Y, Tan LJ, Grachtchouk V, Voorhees JJ, Fisher GJ.

J Biol Chem. 2005 Dec 30;280(52):42694-700. Epub 2005 Oct 31.


Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery.

Tagalakis AD, He L, Saraiva L, Gustafsson KT, Hart SL.

Biomaterials. 2011 Sep;32(26):6302-15. doi: 10.1016/j.biomaterials.2011.05.022. Epub 2011 May 31.


Poly-L-arginine and dextran sulfate-based nanocomplex for epidermal growth factor receptor (EGFR) siRNA delivery: its application for head and neck cancer treatment.

Cho HJ, Chong S, Chung SJ, Shim CK, Kim DD.

Pharm Res. 2012 Apr;29(4):1007-19. doi: 10.1007/s11095-011-0642-z. Epub 2011 Dec 15.


Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods.

Puvanakrishnan P, Diagaradjane P, Kazmi SM, Dunn AK, Krishnan S, Tunnell JW.

Lasers Surg Med. 2012 Apr;44(4):310-7. doi: 10.1002/lsm.22019. Epub 2012 Mar 13.


Protein C is an autocrine growth factor for human skin keratinocytes.

Xue M, Campbell D, Jackson CJ.

J Biol Chem. 2007 May 4;282(18):13610-6. Epub 2007 Feb 9.


Therapeutic effects on atopic dermatitis by anti-RelA short interfering RNA combined with functional peptides Tat and AT1002.

Uchida T, Kanazawa T, Kawai M, Takashima Y, Okada H.

J Pharmacol Exp Ther. 2011 Aug;338(2):443-50. doi: 10.1124/jpet.111.180042. Epub 2011 Apr 29.

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