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Results: 1 to 20 of 96

1.

Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy.

Denmeade SR, Mhaka AM, Rosen DM, Brennen WN, Dalrymple S, Dach I, Olesen C, Gurel B, Demarzo AM, Wilding G, Carducci MA, Dionne CA, Møller JV, Nissen P, Christensen SB, Isaacs JT.

Sci Transl Med. 2012 Jun 27;4(140):140ra86. doi: 10.1126/scitranslmed.3003886. Erratum in: Sci Transl Med. 2012 Jul 18;4(143):143er4.

PMID:
22745436
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Use of methotrexate-based peptide substrates to characterize the substrate specificity of prostate-specific membrane antigen (PSMA).

Mhaka A, Gady AM, Rosen DM, Lo KM, Gillies SD, Denmeade SR.

Cancer Biol Ther. 2004 Jun;3(6):551-8. Epub 2004 Jun 10.

PMID:
15044850
[PubMed - indexed for MEDLINE]
Free Article
3.

In vitro and in vivo responses of advanced prostate tumors to PSMA ADC, an auristatin-conjugated antibody to prostate-specific membrane antigen.

Wang X, Ma D, Olson WC, Heston WD.

Mol Cancer Ther. 2011 Sep;10(9):1728-39. doi: 10.1158/1535-7163.MCT-11-0191. Epub 2011 Jul 12.

PMID:
21750220
[PubMed - indexed for MEDLINE]
Free Article
4.

Prostate-specific membrane antigen targeted imaging and therapy of prostate cancer using a PSMA inhibitor as a homing ligand.

Kularatne SA, Wang K, Santhapuram HK, Low PS.

Mol Pharm. 2009 May-Jun;6(3):780-9. doi: 10.1021/mp900069d.

PMID:
19361233
[PubMed - indexed for MEDLINE]
5.

A dimeric peptide that binds selectively to prostate-specific membrane antigen and inhibits its enzymatic activity.

Aggarwal S, Singh P, Topaloglu O, Isaacs JT, Denmeade SR.

Cancer Res. 2006 Sep 15;66(18):9171-7.

PMID:
16982760
[PubMed - indexed for MEDLINE]
Free Article
6.

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer.

Denmeade SR, Jakobsen CM, Janssen S, Khan SR, Garrett ES, Lilja H, Christensen SB, Isaacs JT.

J Natl Cancer Inst. 2003 Jul 2;95(13):990-1000.

PMID:
12837835
[PubMed - indexed for MEDLINE]
Free Article
7.

The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer.

Denmeade SR, Isaacs JT.

Cancer Biol Ther. 2005 Jan;4(1):14-22. Epub 2005 Jan 23. Review.

PMID:
15662118
[PubMed - indexed for MEDLINE]
Free Article
8.

Potent antitumor activity of an auristatin-conjugated, fully human monoclonal antibody to prostate-specific membrane antigen.

Ma D, Hopf CE, Malewicz AD, Donovan GP, Senter PD, Goeckeler WF, Maddon PJ, Olson WC.

Clin Cancer Res. 2006 Apr 15;12(8):2591-6.

PMID:
16638870
[PubMed - indexed for MEDLINE]
Free Article
9.

Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug.

Brennen WN, Rosen DM, Wang H, Isaacs JT, Denmeade SR.

J Natl Cancer Inst. 2012 Sep 5;104(17):1320-34. doi: 10.1093/jnci/djs336. Epub 2012 Aug 21.

PMID:
22911669
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Assessment of an 18F-labeled phosphoramidate peptidomimetic as a new prostate-specific membrane antigen-targeted imaging agent for prostate cancer.

Lapi SE, Wahnishe H, Pham D, Wu LY, Nedrow-Byers JR, Liu T, Vejdani K, VanBrocklin HF, Berkman CE, Jones EF.

J Nucl Med. 2009 Dec;50(12):2042-8. doi: 10.2967/jnumed.109.066589. Epub 2009 Nov 12.

PMID:
19910433
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector.

Williams BJ, Bhatia S, Adams LK, Boling S, Carroll JL, Li XL, Rogers DL, Korokhov N, Kovesdi I, Pereboev AV, Curiel DT, Mathis JM.

PLoS One. 2012;7(10):e46981. doi: 10.1371/journal.pone.0046981. Epub 2012 Oct 8.

PMID:
23056548
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Anti-tumor effects and lack of side effects in mice of an immunotoxin directed against human and mouse prostate-specific membrane antigen.

Huang X, Bennett M, Thorpe PE.

Prostate. 2004 Sep 15;61(1):1-11.

PMID:
15287089
[PubMed - indexed for MEDLINE]
13.

Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: implications for PSA surrogacy.

Kuroda K, Liu H, Kim S, Guo M, Navarro V, Bander NH.

Prostate. 2009 Oct 1;69(14):1579-85. doi: 10.1002/pros.21004.

PMID:
19575420
[PubMed - indexed for MEDLINE]
14.

Cloning and characterization of canine prostate-specific membrane antigen.

Schmidt S, Fracasso G, Colombatti M, Naim HY.

Prostate. 2013 May;73(6):642-50. doi: 10.1002/pros.22605. Epub 2013 Jan 28.

PMID:
23359458
[PubMed - indexed for MEDLINE]
15.

Preclinical evaluation of a recombinant anti-prostate specific membrane antigen single-chain immunotoxin against prostate cancer.

Wolf P, Alt K, Wetterauer D, Bühler P, Gierschner D, Katzenwadel A, Wetterauer U, Elsässer-Beile U.

J Immunother. 2010 Apr;33(3):262-71. doi: 10.1097/CJI.0b013e3181c5495c.

PMID:
20445346
[PubMed - indexed for MEDLINE]
16.

Paclitaxel-loaded iron platinum stealth immunomicelles are potent MRI imaging agents that prevent prostate cancer growth in a PSMA-dependent manner.

Taylor RM, Sillerud LO.

Int J Nanomedicine. 2012;7:4341-52. doi: 10.2147/IJN.S34381. Epub 2012 Aug 6.

PMID:
22915856
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy.

Wu X, Ding B, Gao J, Wang H, Fan W, Wang X, Zhang W, Wang X, Ye L, Zhang M, Ding X, Liu J, Zhu Q, Gao S.

Int J Nanomedicine. 2011;6:1747-56. doi: 10.2147/IJN.S23747. Epub 2011 Aug 19.

PMID:
21980237
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

PSMA-targeted dendrimers: a patent evaluation (WO2012078534).

Akhtar NH, Osborne JR, Fareedy SB, Tagawa ST.

Expert Opin Ther Pat. 2013 May;23(5):665-8. doi: 10.1517/13543776.2013.789501. Epub 2013 Apr 13.

PMID:
23581819
[PubMed - indexed for MEDLINE]
19.

Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells.

Vander Griend DJ, Antony L, Dalrymple SL, Xu Y, Christensen SB, Denmeade SR, Isaacs JT.

Mol Cancer Ther. 2009 May;8(5):1340-9. doi: 10.1158/1535-7163.MCT-08-1136. Epub 2009 May 5.

PMID:
19417145
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Prostate specific membrane antigen (PSMA): a novel modulator of p38 for proliferation, migration, and survival in prostate cancer cells.

Zhang Y, Guo Z, Du T, Chen J, Wang W, Xu K, Lin T, Huang H.

Prostate. 2013 Jun;73(8):835-41. doi: 10.1002/pros.22627. Epub 2012 Dec 19.

PMID:
23255296
[PubMed - indexed for MEDLINE]
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