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Items: 1 to 20 of 223

1.

A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.

Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D 3rd, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W.

Mol Cell. 2012 Jul 13;47(1):61-75. doi: 10.1016/j.molcel.2012.05.026. Epub 2012 Jun 14.

2.

Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair.

Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4491-6. doi: 10.1073/pnas.1118720109. Epub 2012 Mar 6.

3.

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.

Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y.

J Biol Chem. 2014 Mar 7;289(10):7003-10. doi: 10.1074/jbc.M113.533976. Epub 2014 Jan 22.

4.

FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.

Ali AM, Pradhan A, Singh TR, Du C, Li J, Wahengbam K, Grassman E, Auerbach AD, Pang Q, Meetei AR.

Blood. 2012 Apr 5;119(14):3285-94. doi: 10.1182/blood-2011-10-385963. Epub 2012 Feb 17.

5.

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.

Sims AE, Spiteri E, Sims RJ 3rd, Arita AG, Lach FP, Landers T, Wurm M, Freund M, Neveling K, Hanenberg H, Auerbach AD, Huang TT.

Nat Struct Mol Biol. 2007 Jun;14(6):564-7. Epub 2007 Apr 25.

PMID:
17460694
6.

Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.

Rego MA, Kolling FW 4th, Vuono EA, Mauro M, Howlett NG.

Blood. 2012 Sep 6;120(10):2109-17. doi: 10.1182/blood-2012-02-410472. Epub 2012 Jul 31.

7.

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ.

Cell. 2007 Apr 20;129(2):289-301. Epub 2007 Apr 5.

8.

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair.

Colnaghi L, Jones MJ, Cotto-Rios XM, Schindler D, Hanenberg H, Huang TT.

Blood. 2011 Feb 17;117(7):2247-56. doi: 10.1182/blood-2010-07-295758. Epub 2010 Oct 22.

9.
10.

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL.

Miles JA, Frost MG, Carroll E, Rowe ML, Howard MJ, Sidhu A, Chaugule VK, Alpi AF, Walden H.

J Biol Chem. 2015 Aug 21;290(34):20995-1006. doi: 10.1074/jbc.M115.675835. Epub 2015 Jul 6.

11.

The Fanconi anemia ID2 complex: dueling saxes at the crossroads.

Boisvert RA, Howlett NG.

Cell Cycle. 2014;13(19):2999-3015. doi: 10.4161/15384101.2014.956475. Review.

12.

Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain.

Lim K, Lee MK, Duong PT, Liu D, Sung S, Choi BS.

FEBS Lett. 2015 Oct 7;589(20 Pt B):3037-43. doi: 10.1016/j.febslet.2015.08.021. Epub 2015 Aug 28.

PMID:
26318859
13.

The genetic and biochemical basis of FANCD2 monoubiquitination.

Rajendra E, Oestergaard VH, Langevin F, Wang M, Dornan GL, Patel KJ, Passmore LA.

Mol Cell. 2014 Jun 5;54(5):858-69. doi: 10.1016/j.molcel.2014.05.001.

14.

Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.

Boisvert RA, Rego MA, Azzinaro PA, Mauro M, Howlett NG.

PLoS One. 2013 Nov 21;8(11):e81387. doi: 10.1371/journal.pone.0081387. eCollection 2013.

15.

Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway.

Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C.

J Biol Chem. 2010 Oct 8;285(41):31525-36. doi: 10.1074/jbc.M110.138206. Epub 2010 Jul 30.

16.

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ.

Mol Cell Biol. 2009 Dec;29(24):6427-37. doi: 10.1128/MCB.00086-09. Epub 2009 Oct 5.

17.

Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.

Joo W, Xu G, Persky NS, Smogorzewska A, Rudge DG, Buzovetsky O, Elledge SJ, Pavletich NP.

Science. 2011 Jul 15;333(6040):312-6. doi: 10.1126/science.1205805.

18.

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex.

Tumini E, Plevani P, Muzi-Falconi M, Marini F.

DNA Repair (Amst). 2011 Feb 7;10(2):149-58. doi: 10.1016/j.dnarep.2010.10.006. Epub 2010 Nov 24.

PMID:
21109493
19.

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.

Raghunandan M, Chaudhury I, Kelich SL, Hanenberg H, Sobeck A.

Cell Cycle. 2015;14(3):342-53. doi: 10.4161/15384101.2014.987614.

20.

Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.

Campbell SJ, Edwards RA, Leung CC, Neculai D, Hodge CD, Dhe-Paganon S, Glover JN.

J Biol Chem. 2012 Jul 6;287(28):23900-10. doi: 10.1074/jbc.M112.359653. Epub 2012 May 15.

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