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Results: 1 to 20 of 123

1.

Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid.

Bergfeld AK, Pearce OM, Diaz SL, Pham T, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28865-81. doi: 10.1074/jbc.M112.363549. Epub 2012 Jun 12.

PMID:
22692205
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Biosynthesis of N-glycolyneuraminic acid. The primary site of hydroxylation of N-acetylneuraminic acid is the cytosolic sugar nucleotide pool.

Muchmore EA, Milewski M, Varki A, Diaz S.

J Biol Chem. 1989 Dec 5;264(34):20216-23.

PMID:
2684973
[PubMed - indexed for MEDLINE]
Free Article
3.

Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine.

Bergfeld AK, Pearce OM, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28898-916. doi: 10.1074/jbc.M112.363499. Epub 2012 Jun 12.

PMID:
22692203
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2-8-linked N-glycolylneuraminic acid to enzymatic cleavage.

Davies LR, Pearce OM, Tessier MB, Assar S, Smutova V, Pajunen M, Sumida M, Sato C, Kitajima K, Finne J, Gagneux P, Pshezhetsky A, Woods R, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28917-31. doi: 10.1074/jbc.M112.365056. Epub 2012 Jun 12.

PMID:
22692207
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Metabolism of vertebrate amino sugars with N-glycolyl groups: mechanisms underlying gastrointestinal incorporation of the non-human sialic acid xeno-autoantigen N-glycolylneuraminic acid.

Banda K, Gregg CJ, Chow R, Varki NM, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28852-64. doi: 10.1074/jbc.M112.364182. Epub 2012 Jun 12.

PMID:
22692204
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

N-glycolylneuraminic acid on human epithelial cells prevents entry of influenza A viruses that possess N-glycolylneuraminic acid binding ability.

Takahashi T, Takano M, Kurebayashi Y, Masuda M, Kawagishi S, Takaguchi M, Yamanaka T, Minami A, Otsubo T, Ikeda K, Suzuki T.

J Virol. 2014 Aug;88(15):8445-56. doi: 10.1128/JVI.00716-14. Epub 2014 May 14.

PMID:
24829344
[PubMed - indexed for MEDLINE]
Free Article
7.

Loss of N-glycolylneuraminic acid in humans: Mechanisms, consequences, and implications for hominid evolution.

Varki A.

Am J Phys Anthropol. 2001;Suppl 33:54-69. Review.

PMID:
11786991
[PubMed - indexed for MEDLINE]
8.

Human CMP-N-acetylneuraminic acid hydroxylase is a novel stem cell marker linked to stem cell-specific mechanisms.

Nystedt J, Anderson H, Hirvonen T, Impola U, Jaatinen T, Heiskanen A, Blomqvist M, Satomaa T, Natunen J, Saarinen J, Lehenkari P, Valmu L, Laine J.

Stem Cells. 2010 Feb;28(2):258-67. doi: 10.1002/stem.250.

PMID:
19890979
[PubMed - indexed for MEDLINE]
Free Article
9.

A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells.

Casadesús AV, Fernández-Marrero Y, Clavell M, Gómez JA, Hernández T, Moreno E, López-Requena A.

Glycoconj J. 2013 Oct;30(7):687-99. doi: 10.1007/s10719-013-9473-y. Epub 2013 Apr 2.

PMID:
23547010
[PubMed - indexed for MEDLINE]
10.

Regulation of N-glycolylneuraminic acid biosynthesis in developing pig small intestine.

Malykh YN, King TP, Logan E, Kelly D, Schauer R, Shaw L.

Biochem J. 2003 Mar 1;370(Pt 2):601-7.

PMID:
12444926
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Extensive enrichment of N-glycolylneuraminic acid in extracellular sialoglycoproteins abundantly synthesized and secreted by human cancer cells.

Inoue S, Sato C, Kitajima K.

Glycobiology. 2010 Jun;20(6):752-62. doi: 10.1093/glycob/cwq030. Epub 2010 Mar 1.

PMID:
20197272
[PubMed - indexed for MEDLINE]
Free Article
12.

Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells.

Bardor M, Nguyen DH, Diaz S, Varki A.

J Biol Chem. 2005 Feb 11;280(6):4228-37. Epub 2004 Nov 22.

PMID:
15557321
[PubMed - indexed for MEDLINE]
Free Article
13.

A study on the regulation of N-glycoloylneuraminic acid biosynthesis and utilization in rat and mouse liver.

Lepers A, Shaw L, Schneckenburger P, Cacan R, Verbert A, Schauer R.

Eur J Biochem. 1990 Nov 13;193(3):715-23.

PMID:
2249689
[PubMed - indexed for MEDLINE]
Free Article
14.

Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation.

Naito Y, Takematsu H, Koyama S, Miyake S, Yamamoto H, Fujinawa R, Sugai M, Okuno Y, Tsujimoto G, Yamaji T, Hashimoto Y, Itohara S, Kawasaki T, Suzuki A, Kozutsumi Y.

Mol Cell Biol. 2007 Apr;27(8):3008-22. Epub 2007 Feb 12.

PMID:
17296732
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The role of CMP-N-acetylneuraminic acid hydroxylase in determining the level of N-glycolylneuraminic acid in porcine tissues.

Malykh YN, Shaw L, Schauer R.

Glycoconj J. 1998 Sep;15(9):885-93.

PMID:
10052592
[PubMed - indexed for MEDLINE]
16.

Distribution and localization of CMP-N-acetylneuraminic acid hydroxylase and N-glycolylneuraminic acid-containing glycoconjugates in porcine lymph node and peripheral blood lymphocytes.

Malykh YN, Krisch B, Shaw L, Warner TG, Sinicropi D, Smith R, Chang J, Schauer R.

Eur J Cell Biol. 2001 Jan;80(1):48-58.

PMID:
11211935
[PubMed - indexed for MEDLINE]
17.

N-glycolylneuraminic acid deficiency in humans.

Varki A.

Biochimie. 2001 Jul;83(7):615-22. Review.

PMID:
11522390
[PubMed - indexed for MEDLINE]
18.

Reduction of CMP-N-acetylneuraminic acid hydroxylase activity in engineered Chinese hamster ovary cells using an antisense-RNA strategy.

Chenu S, Grégoire A, Malykh Y, Visvikis A, Monaco L, Shaw L, Schauer R, Marc A, Goergen JL.

Biochim Biophys Acta. 2003 Jul 23;1622(2):133-44.

PMID:
12880951
[PubMed - indexed for MEDLINE]
19.

Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid.

Taylor RE, Gregg CJ, Padler-Karavani V, Ghaderi D, Yu H, Huang S, Sorensen RU, Chen X, Inostroza J, Nizet V, Varki A.

J Exp Med. 2010 Aug 2;207(8):1637-46. doi: 10.1084/jem.20100575. Epub 2010 Jul 12.

PMID:
20624889
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution.

Hedlund M, Tangvoranuntakul P, Takematsu H, Long JM, Housley GD, Kozutsumi Y, Suzuki A, Wynshaw-Boris A, Ryan AF, Gallo RL, Varki N, Varki A.

Mol Cell Biol. 2007 Jun;27(12):4340-6. Epub 2007 Apr 9.

PMID:
17420276
[PubMed - indexed for MEDLINE]
Free PMC Article

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