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Results: 1 to 20 of 85

1.

EphrinA1 is released in three forms from cancer cells by matrix metalloproteases.

Beauchamp A, Lively MO, Mintz A, Gibo D, Wykosky J, Debinski W.

Mol Cell Biol. 2012 Aug;32(16):3253-64. doi: 10.1128/MCB.06791-11. Epub 2012 Jun 11.

PMID:
22688511
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor.

Wykosky J, Palma E, Gibo DM, Ringler S, Turner CP, Debinski W.

Oncogene. 2008 Dec 11;27(58):7260-73. doi: 10.1038/onc.2008.328. Epub 2008 Sep 15.

PMID:
18794797
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

EphA2 as a novel molecular marker and target in glioblastoma multiforme.

Wykosky J, Gibo DM, Stanton C, Debinski W.

Mol Cancer Res. 2005 Oct;3(10):541-51.

PMID:
16254188
[PubMed - indexed for MEDLINE]
Free Article
4.

Structural and functional characterization of monomeric EphrinA1 binding site to EphA2 receptor.

Lema Tomé CM, Palma E, Ferluga S, Lowther WT, Hantgan R, Wykosky J, Debinski W.

J Biol Chem. 2012 Apr 20;287(17):14012-22. doi: 10.1074/jbc.M111.311670. Epub 2012 Feb 23.

PMID:
22362770
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

EphrinA1-EphA2 interaction-mediated apoptosis and FMS-like tyrosine kinase 3 receptor ligand-induced immunotherapy inhibit tumor growth in a breast cancer mouse model.

Tandon M, Vemula SV, Sharma A, Ahi YS, Mittal S, Bangari DS, Mittal SK.

J Gene Med. 2012 Feb;14(2):77-89. doi: 10.1002/jgm.1649.

PMID:
22228563
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells.

Wykosky J, Gibo DM, Debinski W.

Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3208-18.

PMID:
18089715
[PubMed - indexed for MEDLINE]
Free Article
7.

Up-regulation of EphA2 and down-regulation of EphrinA1 are associated with the aggressive phenotype and poor prognosis of malignant glioma.

Li X, Wang L, Gu JW, Li B, Liu WP, Wang YG, Zhang X, Zhen HN, Fei Z.

Tumour Biol. 2010 Oct;31(5):477-88. doi: 10.1007/s13277-010-0060-6. Epub 2010 Jun 23.

PMID:
20571968
[PubMed - indexed for MEDLINE]
8.

The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting.

Wykosky J, Debinski W.

Mol Cancer Res. 2008 Dec;6(12):1795-806. doi: 10.1158/1541-7786.MCR-08-0244. Review.

PMID:
19074825
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cell adhesion and EGFR activation regulate EphA2 expression in cancer.

Larsen AB, Stockhausen MT, Poulsen HS.

Cell Signal. 2010 Apr;22(4):636-44. doi: 10.1016/j.cellsig.2009.11.018. Epub 2009 Dec 2.

PMID:
19948216
[PubMed - indexed for MEDLINE]
10.

Receptor EphA2 activation with ephrinA1 suppresses growth of malignant mesothelioma (MM).

Nasreen N, Mohammed KA, Lai Y, Antony VB.

Cancer Lett. 2007 Dec 18;258(2):215-22. Epub 2007 Oct 18.

PMID:
17949899
[PubMed - indexed for MEDLINE]
11.

Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

Noblitt LW, Bangari DS, Shukla S, Knapp DW, Mohammed S, Kinch MS, Mittal SK.

Cancer Gene Ther. 2004 Nov;11(11):757-66.

PMID:
15359289
[PubMed - indexed for MEDLINE]
12.

EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.

Khodayari N, Mohammed KA, Goldberg EP, Nasreen N.

Cancer Gene Ther. 2011 Nov;18(11):806-16. doi: 10.1038/cgt.2011.50. Epub 2011 Aug 26.

PMID:
21869823
[PubMed - indexed for MEDLINE]
13.

EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating Ezrin through negative regulation of RhoA.

Wakayama Y, Miura K, Sabe H, Mochizuki N.

J Biol Chem. 2011 Dec 23;286(51):44243-53. doi: 10.1074/jbc.M111.267047. Epub 2011 Oct 6.

PMID:
21979959
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.

Greene AC, Lord SJ, Tian A, Rhodes C, Kai H, Groves JT.

Biophys J. 2014 May 20;106(10):2196-205. doi: 10.1016/j.bpj.2014.03.043.

PMID:
24853748
[PubMed - indexed for MEDLINE]
15.

EphA2 receptor activation by monomeric Ephrin-A1 on supported membranes.

Xu Q, Lin WC, Petit RS, Groves JT.

Biophys J. 2011 Dec 7;101(11):2731-9. doi: 10.1016/j.bpj.2011.10.039.

PMID:
22261062
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility.

Parri M, Buricchi F, Giannoni E, Grimaldi G, Mello T, Raugei G, Ramponi G, Chiarugi P.

J Biol Chem. 2007 Jul 6;282(27):19619-28. Epub 2007 Apr 22.

PMID:
17449913
[PubMed - indexed for MEDLINE]
Free Article
17.

Structure-activity relationships and mechanism of action of Eph-ephrin antagonists: interaction of cholanic acid with the EphA2 receptor.

Tognolini M, Incerti M, Hassan-Mohamed I, Giorgio C, Russo S, Bruni R, Lelli B, Bracci L, Noberini R, Pasquale EB, Barocelli E, Vicini P, Mor M, Lodola A.

ChemMedChem. 2012 Jun;7(6):1071-83. doi: 10.1002/cmdc.201200102. Epub 2012 Apr 23.

PMID:
22529030
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ephrin-A1 inhibits NSCLC tumor growth via induction of Cdx-2 a tumor suppressor gene.

Sukka-Ganesh B, Mohammed KA, Kaye F, Goldberg EP, Nasreen N.

BMC Cancer. 2012 Jul 23;12:309. doi: 10.1186/1471-2407-12-309.

PMID:
22824143
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase.

Parri M, Buricchi F, Taddei ML, Giannoni E, Raugei G, Ramponi G, Chiarugi P.

J Biol Chem. 2005 Oct 7;280(40):34008-18. Epub 2005 Jul 28.

PMID:
16051609
[PubMed - indexed for MEDLINE]
Free Article
20.

Degradation of tropoelastin by matrix metalloproteinases--cleavage site specificities and release of matrikines.

Heinz A, Jung MC, Duca L, Sippl W, Taddese S, Ihling C, Rusciani A, Jahreis G, Weiss AS, Neubert RH, Schmelzer CE.

FEBS J. 2010 Apr;277(8):1939-56. doi: 10.1111/j.1742-4658.2010.07616.x. Epub 2010 Mar 22.

PMID:
20345904
[PubMed - indexed for MEDLINE]
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