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Results: 1 to 20 of 98

1.

Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection.

Fang M, Siciliano NA, Hersperger AR, Roscoe F, Hu A, Ma X, Shamsedeen AR, Eisenlohr LC, Sigal LJ.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9983-8. doi: 10.1073/pnas.1202143109. Epub 2012 Jun 4.

PMID:
22665800
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Different roles for CD4+ and CD8+ T lymphocytes and macrophage subsets in the control of a generalized virus infection.

Karupiah G, Buller RM, Van Rooijen N, Duarte CJ, Chen J.

J Virol. 1996 Dec;70(12):8301-9.

PMID:
8970949
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.

Brown DM, Kamperschroer C, Dilzer AM, Roberts DM, Swain SL.

Cell Immunol. 2009;257(1-2):69-79. doi: 10.1016/j.cellimm.2009.03.002. Epub 2009 Mar 31.

PMID:
19338979
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection.

Brown DM, Lee S, Garcia-Hernandez Mde L, Swain SL.

J Virol. 2012 Jun;86(12):6792-803. doi: 10.1128/JVI.07172-11. Epub 2012 Apr 4.

PMID:
22491469
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pathogenesis of mousepox in H-2(d) mice: evidence for MHC class I-restricted CD8(+) and MHC class II-restricted CD4(+) CTL antiviral activity in the lymph nodes, spleen and skin, but not in the conjunctivae.

Cespedes IS, Toka FN, Schollenberger A, Gieryńska M, Niemiałtowski M.

Microbes Infect. 2001 Nov;3(13):1063-72.

PMID:
11709286
[PubMed - indexed for MEDLINE]
6.

Induction of natural killer cell responses by ectromelia virus controls infection.

Parker AK, Parker S, Yokoyama WM, Corbett JA, Buller RM.

J Virol. 2007 Apr;81(8):4070-9. Epub 2007 Feb 7.

PMID:
17287257
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes.

Müllbacher A, Waring P, Tha Hla R, Tran T, Chin S, Stehle T, Museteanu C, Simon MM.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13950-5.

PMID:
10570179
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells.

Bergmann CC, Parra B, Hinton DR, Ramakrishna C, Dowdell KC, Stohlman SA.

J Virol. 2004 Feb;78(4):1739-50.

PMID:
14747539
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Clearance of HIV type 1 envelope recombinant sendai virus depends on CD4+ T cells and interferon-gamma but not B cells, CD8+ T cells, or perforin.

Surman SL, Brown SA, Jones BG, Woodland DL, Hurwitz JL.

AIDS Res Hum Retroviruses. 2010 Jul;26(7):783-93. doi: 10.1089/aid.2009.0266.

PMID:
20623995
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections.

Hansen AK, Regner M, Bonefeld CM, Boding L, Kongsbak M, Ødum N, Müllbacher A, Geisler C, von Essen MR.

Eur J Immunol. 2011 Jul;41(7):1948-57. doi: 10.1002/eji.201141413. Epub 2011 May 27.

PMID:
21590764
[PubMed - indexed for MEDLINE]
11.

A role for early cytotoxic T cells in resistance to ectromelia virus infection in mice.

O'Neill HC, Brenan M.

J Gen Virol. 1987 Oct;68 ( Pt 10):2669-73.

PMID:
2822845
[PubMed - indexed for MEDLINE]
Free Article
12.

Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.

Kafrouni MI, Brown GR, Thiele DL.

J Immunol. 2001 Aug 1;167(3):1566-74.

PMID:
11466378
[PubMed - indexed for MEDLINE]
Free Article
13.

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection.

Remakus S, Rubio D, Lev A, Ma X, Fang M, Xu RH, Sigal LJ.

Cell Host Microbe. 2013 May 15;13(5):546-57. doi: 10.1016/j.chom.2013.04.004.

PMID:
23684306
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Protective immunity against secondary poxvirus infection is dependent on antibody but not on CD4 or CD8 T-cell function.

Panchanathan V, Chaudhri G, Karupiah G.

J Virol. 2006 Jul;80(13):6333-8.

PMID:
16775321
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection.

Matloubian M, Concepcion RJ, Ahmed R.

J Virol. 1994 Dec;68(12):8056-63.

PMID:
7966595
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

Williams NS, Engelhard VH.

J Immunol. 1996 Jan 1;156(1):153-9.

PMID:
8598456
[PubMed - indexed for MEDLINE]
17.

Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.

Woodworth JS, Wu Y, Behar SM.

J Immunol. 2008 Dec 15;181(12):8595-603.

PMID:
19050279
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human purified protein derivative-specific CD4+ T cells use both CD95-dependent and CD95-independent cytolytic mechanisms.

Lewinsohn DM, Bement TT, Xu J, Lynch DH, Grabstein KH, Reed SG, Alderson MR.

J Immunol. 1998 Mar 1;160(5):2374-9.

PMID:
9498779
[PubMed - indexed for MEDLINE]
Free Article
20.

CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.

Stohlman SA, Hinton DR, Parra B, Atkinson R, Bergmann CC.

J Virol. 2008 Mar;82(5):2130-9. Epub 2007 Dec 19.

PMID:
18094171
[PubMed - indexed for MEDLINE]
Free PMC Article

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