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Items: 1 to 20 of 171

1.

Regulation of hepatic stellate cells by connective tissue growth factor.

Huang G, Brigstock DR.

Front Biosci (Landmark Ed). 2012 Jun 1;17:2495-507. Review.

PMID:
22652794
2.

Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes.

Gressner OA, Lahme B, Demirci I, Gressner AM, Weiskirchen R.

J Hepatol. 2007 Nov;47(5):699-710. Epub 2007 Jun 26.

PMID:
17629588
3.

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes.

Tong Z, Chen R, Alt DS, Kemper S, Perbal B, Brigstock DR.

Hepatology. 2009 Sep;50(3):939-47. doi: 10.1002/hep.23102.

4.

Transforming growth factor-β (TGF-β)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activation.

Liu Y, Liu H, Meyer C, Li J, Nadalin S, Königsrainer A, Weng H, Dooley S, ten Dijke P.

J Biol Chem. 2013 Oct 18;288(42):30708-19. doi: 10.1074/jbc.M113.478685. Epub 2013 Sep 4.

5.

Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2).

Huang G, Brigstock DR.

J Cell Mol Med. 2011 May;15(5):1087-95. doi: 10.1111/j.1582-4934.2010.01072.x. Epub 2010 Apr 19.

6.

CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes.

Fujisawa T, Hattori T, Ono M, Uehara J, Kubota S, Kuboki T, Takigawa M.

Osteoarthritis Cartilage. 2008 Jul;16(7):787-95. doi: 10.1016/j.joca.2007.11.001. Epub 2008 Mar 4.

7.

Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis.

Rachfal AW, Brigstock DR.

Hepatol Res. 2003 May;26(1):1-9.

PMID:
12787797
8.

[Effect of shRNA-mediated silencing of CTGF and TIMP-1 on mRNA expression of CTGF, TIMP-1, and PC I and secretion of extracellular matrix in rat hepatic stellate cells].

Jiang YF, Sun HL, Zhang JJ, Huang F, Liu JQ.

Zhonghua Gan Zang Bing Za Zhi. 2012 Aug;20(8):576-80. doi: 10.3760/cma.j.issn.1007-3418.2012.08.007. Chinese.

PMID:
23207149
9.

Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells.

Chen L, Charrier A, Zhou Y, Chen R, Yu B, Agarwal K, Tsukamoto H, Lee LJ, Paulaitis ME, Brigstock DR.

Hepatology. 2014 Mar;59(3):1118-29. doi: 10.1002/hep.26768. Epub 2014 Jan 27.

10.

Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2).

Charrier A, Brigstock DR.

Cytokine Growth Factor Rev. 2013 Feb;24(1):59-68. doi: 10.1016/j.cytogfr.2012.07.001. Epub 2012 Aug 10. Review.

11.

CTGF/CCN2 exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1/S1P3 signaling axis: Implications in the action mechanism of TGFβ.

Bruno G, Cencetti F, Pertici I, Japtok L, Bernacchioni C, Donati C, Bruni P.

Biochim Biophys Acta. 2015 Feb;1851(2):194-202. doi: 10.1016/j.bbalip.2014.11.011. Epub 2014 Nov 29.

PMID:
25457224
12.

Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo.

Hao C, Xie Y, Peng M, Ma L, Zhou Y, Zhang Y, Kang W, Wang J, Bai X, Wang P, Jia Z.

Clin Exp Med. 2014 May;14(2):141-50. doi: 10.1007/s10238-013-0229-6. Epub 2013 Mar 2.

PMID:
23456538
13.

Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases.

Gressner OA, Gressner AM.

Liver Int. 2008 Sep;28(8):1065-79. doi: 10.1111/j.1478-3231.2008.01826.x. Review.

PMID:
18783549
14.

Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver.

Charrier A, Chen R, Chen L, Kemper S, Hattori T, Takigawa M, Brigstock DR.

Surgery. 2014 Sep;156(3):548-55. doi: 10.1016/j.surg.2014.04.014. Epub 2014 Jun 2.

15.

Effect of transforming growth factor-beta1 on expression of the connective tissue growth factor (CCN2/CTGF) gene in normal human gingival fibroblasts and periodontal ligament cells.

Takeuchi H, Kubota S, Murakashi E, Fukada T, Hashimoto S, Takigawa M, Numabe Y.

J Periodontal Res. 2009 Apr;44(2):161-9. doi: 10.1111/j.1600-0765.2008.01093.x. Epub 2008 Feb 6.

PMID:
19210343
16.

Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β.

Kawelke N, Vasel M, Sens C, Au Av, Dooley S, Nakchbandi IA.

PLoS One. 2011;6(11):e28181. doi: 10.1371/journal.pone.0028181. Epub 2011 Nov 28.

17.
18.

Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1.

Chen L, Chen R, Kemper S, Charrier A, Brigstock DR.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G491-9. doi: 10.1152/ajpgi.00140.2015. Epub 2015 Jul 30.

PMID:
26229009
19.

Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2).

Charrier A, Chen R, Kemper S, Brigstock DR.

Immunology. 2014 Apr;141(4):564-76.

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