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Results: 1 to 20 of 107

1.

Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra.

McCormack AL, Mak SK, Di Monte DA.

Cell Death Dis. 2012 May 31;3:e315. doi: 10.1038/cddis.2012.50.

PMID:
22647852
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates.

Purisai MG, McCormack AL, Langston WJ, Johnston LC, Di Monte DA.

Neurobiol Dis. 2005 Dec;20(3):898-906. Epub 2005 Jul 11.

PMID:
16006134
[PubMed - indexed for MEDLINE]
3.

Decreased alpha-synuclein expression in the aging mouse substantia nigra.

Mak SK, McCormack AL, Langston JW, Kordower JH, Di Monte DA.

Exp Neurol. 2009 Dec;220(2):359-65. doi: 10.1016/j.expneurol.2009.09.021. Epub 2009 Oct 1.

PMID:
19800328
[PubMed - indexed for MEDLINE]
4.

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

Halliday GM, Ophof A, Broe M, Jensen PH, Kettle E, Fedorow H, Cartwright MI, Griffiths FM, Shepherd CE, Double KL.

Brain. 2005 Nov;128(Pt 11):2654-64. Epub 2005 Jul 6.

PMID:
16000336
[PubMed - indexed for MEDLINE]
Free Article
5.

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.

St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ.

J Neurochem. 2007 Mar;100(6):1449-57. Epub 2007 Jan 4.

PMID:
17241127
[PubMed - indexed for MEDLINE]
7.

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, Przedborski S.

J Neurochem. 2000 Feb;74(2):721-9.

PMID:
10646524
[PubMed - indexed for MEDLINE]
8.

Oxidation and nitration of α-synuclein and their implications in neurodegenerative diseases.

Chavarría C, Souza JM.

Arch Biochem Biophys. 2013 May;533(1-2):25-32. doi: 10.1016/j.abb.2013.02.009. Epub 2013 Feb 27. Review.

PMID:
23454347
[PubMed - indexed for MEDLINE]
9.

Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice.

Al-Wandi A, Ninkina N, Millership S, Williamson SJ, Jones PA, Buchman VL.

Neurobiol Aging. 2010 May;31(5):796-804. doi: 10.1016/j.neurobiolaging.2008.11.001. Epub 2008 Dec 20.

PMID:
19097673
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ageing enhances alpha-synuclein, ubiquitin and endoplasmic reticular stress protein expression in the nigral neurons of Asian Indians.

Alladi PA, Mahadevan A, Vijayalakshmi K, Muthane U, Shankar SK, Raju TR.

Neurochem Int. 2010 Nov;57(5):530-9. doi: 10.1016/j.neuint.2010.06.018. Epub 2010 Jul 6.

PMID:
20615443
[PubMed - indexed for MEDLINE]
11.

Nitrated alpha-synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats.

Yu Z, Xu X, Xiang Z, Zhou J, Zhang Z, Hu C, He C.

PLoS One. 2010 Apr 8;5(4):e9956. doi: 10.1371/journal.pone.0009956.

PMID:
20386702
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pathologic modifications of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated squirrel monkeys.

McCormack AL, Mak SK, Shenasa M, Langston WJ, Forno LS, Di Monte DA.

J Neuropathol Exp Neurol. 2008 Aug;67(8):793-802. doi: 10.1097/NEN.0b013e318180f0bd.

PMID:
18648323
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease.

Ferrer I, Martinez A, Blanco R, Dalfó E, Carmona M.

J Neural Transm. 2011 May;118(5):821-39. doi: 10.1007/s00702-010-0482-8. Epub 2010 Sep 23. Review.

PMID:
20862500
[PubMed - indexed for MEDLINE]
14.

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.

Benner EJ, Banerjee R, Reynolds AD, Sherman S, Pisarev VM, Tsiperson V, Nemachek C, Ciborowski P, Przedborski S, Mosley RL, Gendelman HE.

PLoS One. 2008 Jan 2;3(1):e1376. doi: 10.1371/journal.pone.0001376.

PMID:
18167537
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra.

Garcia-Reitboeck P, Anichtchik O, Dalley JW, Ninkina N, Tofaris GK, Buchman VL, Spillantini MG.

Exp Neurol. 2013 Oct;248:541-5. doi: 10.1016/j.expneurol.2013.07.015. Epub 2013 Aug 8.

PMID:
23933574
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Specificity and regulation of casein kinase-mediated phosphorylation of alpha-synuclein.

Waxman EA, Giasson BI.

J Neuropathol Exp Neurol. 2008 May;67(5):402-16. doi: 10.1097/NEN.0b013e31816fc995.

PMID:
18451726
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.

McCormack AL, Mak SK, Henderson JM, Bumcrot D, Farrer MJ, Di Monte DA.

PLoS One. 2010 Aug 11;5(8):e12122. doi: 10.1371/journal.pone.0012122.

PMID:
20711464
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Relationship between mitochondria and α-synuclein: a study of single substantia nigra neurons.

Reeve AK, Park TK, Jaros E, Campbell GR, Lax NZ, Hepplewhite PD, Krishnan KJ, Elson JL, Morris CM, McKeith IG, Turnbull DM.

Arch Neurol. 2012 Mar;69(3):385-93. doi: 10.1001/archneurol.2011.2675.

PMID:
22410447
[PubMed - indexed for MEDLINE]
19.

The nigro-striatal and nigro-amygdaloid pathways undergo different degeneration processes in brains of dementia with Lewy bodies.

Iseki E, Marui W, Yamamoto R, Togo T, Katsuse O, Kato M, Iwatsubo T, Kosaka K, Arai H.

Neurosci Lett. 2005 May 20-27;380(1-2):161-5. Epub 2005 Feb 3.

PMID:
15854770
[PubMed - indexed for MEDLINE]
20.

Authentically phosphorylated α-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease.

Sato H, Arawaka S, Hara S, Fukushima S, Koga K, Koyama S, Kato T.

J Neurosci. 2011 Nov 16;31(46):16884-94. doi: 10.1523/JNEUROSCI.3967-11.2011.

PMID:
22090514
[PubMed - indexed for MEDLINE]
Free Article

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