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Temporal coding of insulin action through multiplexing of the AKT pathway.

Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, Ogawa W, Kuroda S.

Mol Cell. 2012 Jun 29;46(6):820-32. doi: 10.1016/j.molcel.2012.04.018. Epub 2012 May 24.


Differential regulation of MAP kinase, p70(S6K), and Akt by contraction and insulin in rat skeletal muscle.

Sherwood DJ, Dufresne SD, Markuns JF, Cheatham B, Moller DE, Aronson D, Goodyear LJ.

Am J Physiol. 1999 May;276(5 Pt 1):E870-8.


Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.

Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM.

Mol Cell Biol. 2004 Oct;24(19):8778-89.


Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).

Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG Jr, Rhodes CJ.

J Biol Chem. 2001 Jun 15;276(24):21110-20. Epub 2001 Mar 27.


The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism.

Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ.

J Biol Chem. 1999 Jun 18;274(25):17934-40.


Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.

Marinho R, Ropelle ER, Cintra DE, De Souza CT, Da Silva AS, Bertoli FC, Colantonio E, D'Almeida V, Pauli JR.

J Cell Physiol. 2012 Jul;227(7):2917-26. doi: 10.1002/jcp.23037.


Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characteristics.

Fujita KA, Toyoshima Y, Uda S, Ozaki Y, Kubota H, Kuroda S.

Sci Signal. 2010 Jul 27;3(132):ra56. doi: 10.1126/scisignal.2000810.


Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity.

Patel S, Lochhead PA, Rena G, Fumagalli S, Pende M, Kozma SC, Thomas G, Sutherland C.

J Biol Chem. 2002 Mar 22;277(12):9889-95. Epub 2002 Jan 9.


P2 purinergic receptors signal to glycogen synthase kinase-3beta in astrocytes.

Neary JT, Kang Y.

J Neurosci Res. 2006 Aug 15;84(3):515-24.


Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination.

Ogata T, Iijima S, Hoshikawa S, Miura T, Yamamoto S, Oda H, Nakamura K, Tanaka S.

J Neurosci. 2004 Jul 28;24(30):6724-32.


PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.

Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.

J Biol Chem. 2005 Jun 10;280(23):22523-9. Epub 2005 Apr 11.


Insulin-regulated protein kinases during postnatal development of rat heart.

Kim SO, Hasham MI, Katz S, Pelech SL.

J Cell Biochem. 1998 Dec 1;71(3):328-39.


Signaling pathways leading to phosphorylation of Akt and GSK-3β by activation of cloned human and rat cerebral D₂and D₃ receptors.

Mannoury la Cour C, Salles MJ, Pasteau V, Millan MJ.

Mol Pharmacol. 2011 Jan;79(1):91-105. doi: 10.1124/mol.110.065409. Epub 2010 Oct 15.

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