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Items: 1 to 20 of 141

1.

IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.

Keady BT, Samtani R, Tobita K, Tsuchya M, San Agustin JT, Follit JA, Jonassen JA, Subramanian R, Lo CW, Pazour GJ.

Dev Cell. 2012 May 15;22(5):940-51. doi: 10.1016/j.devcel.2012.04.009.

2.

Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.

Yang N, Li L, Eguether T, Sundberg JP, Pazour GJ, Chen J.

Development. 2015 Jun 15;142(12):2194-202. doi: 10.1242/dev.115261. Epub 2015 May 28. Erratum in: Development. 2015 Aug 15;142(16):2860.

3.

IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.

Eguether T, San Agustin JT, Keady BT, Jonassen JA, Liang Y, Francis R, Tobita K, Johnson CA, Abdelhamed ZA, Lo CW, Pazour GJ.

Dev Cell. 2014 Nov 10;31(3):279-90. doi: 10.1016/j.devcel.2014.09.011. Epub 2014 Oct 30.

4.

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.

Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61. doi: 10.1073/pnas.1011410108. Epub 2011 Jan 5.

5.

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.

Liem KF Jr, Ashe A, He M, Satir P, Moran J, Beier D, Wicking C, Anderson KV.

J Cell Biol. 2012 Jun 11;197(6):789-800. doi: 10.1083/jcb.201110049.

6.

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts.

Ocbina PJ, Anderson KV.

Dev Dyn. 2008 Aug;237(8):2030-8. doi: 10.1002/dvdy.21551.

7.

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.

Clement CA, Kristensen SG, Møllgård K, Pazour GJ, Yoder BK, Larsen LA, Christensen ST.

J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82. doi: 10.1242/jcs.049676. Epub 2009 Aug 4.

8.

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, Scales SJ.

Mol Cell Biol. 2010 Apr;30(8):1910-22. doi: 10.1128/MCB.01089-09. Epub 2010 Feb 12.

9.

Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.

Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A.

Dev Biol. 2009 Jan 1;325(1):225-37. doi: 10.1016/j.ydbio.2008.10.020. Epub 2008 Oct 29.

10.

ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.

Chaya T, Omori Y, Kuwahara R, Furukawa T.

EMBO J. 2014 Jun 2;33(11):1227-42. doi: 10.1002/embj.201488175. Epub 2014 May 5.

11.

Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.

Wang C, Low WC, Liu A, Wang B.

J Biol Chem. 2013 Oct 11;288(41):29518-29. doi: 10.1074/jbc.M113.492066. Epub 2013 Aug 16.

12.

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.

Friedland-Little JM, Hoffmann AD, Ocbina PJ, Peterson MA, Bosman JD, Chen Y, Cheng SY, Anderson KV, Moskowitz IP.

Hum Mol Genet. 2011 Oct 1;20(19):3725-37. doi: 10.1093/hmg/ddr241. Epub 2011 Jun 8.

13.

G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.

Hwang SH, Mukhopadhyay S.

Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):12-9. doi: 10.1002/bdra.23267. Epub 2014 Jun 11.

PMID:
24917297
14.

Cilia and Hedgehog responsiveness in the mouse.

Huangfu D, Anderson KV.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30. Epub 2005 Aug 1.

15.

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, Herron BJ, Chesebro AL, Qiu H, Scherz PJ, Shah JV, Yoder BK, Beier DR.

Nat Genet. 2008 Apr;40(4):403-10. doi: 10.1038/ng.105. Epub 2008 Mar 9.

PMID:
18327258
16.

Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.

Larkins CE, Aviles GD, East MP, Kahn RA, Caspary T.

Mol Biol Cell. 2011 Dec;22(23):4694-703. doi: 10.1091/mbc.E10-12-0994. Epub 2011 Oct 5.

17.

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli.

May SR, Ashique AM, Karlen M, Wang B, Shen Y, Zarbalis K, Reiter J, Ericson J, Peterson AS.

Dev Biol. 2005 Nov 15;287(2):378-89. Epub 2005 Oct 17.

18.

The primary cilium as a Hedgehog signal transduction machine.

Goetz SC, Ocbina PJ, Anderson KV.

Methods Cell Biol. 2009;94:199-222. doi: 10.1016/S0091-679X(08)94010-3. Epub 2009 Dec 23.

19.

The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis.

Yang S, Wang C.

Bone. 2012 Sep;51(3):407-17. doi: 10.1016/j.bone.2012.06.021. Epub 2012 Jul 4.

20.

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.

Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK.

PLoS Genet. 2005 Oct;1(4):e53. Epub 2005 Oct 28.

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