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Results: 1 to 20 of 96

1.

TDP-43 identified from a genome wide RNAi screen for SOD1 regulators.

Somalinga BR, Day CE, Wei S, Roth MG, Thomas PJ.

PLoS One. 2012;7(4):e35818. doi: 10.1371/journal.pone.0035818. Epub 2012 Apr 26.

PMID:
22563406
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.

Maekawa S, Leigh PN, King A, Jones E, Steele JC, Bodi I, Shaw CE, Hortobagyi T, Al-Sarraj S.

Neuropathology. 2009 Dec;29(6):672-83. doi: 10.1111/j.1440-1789.2009.01029.x. Epub 2009 Jun 3.

PMID:
19496940
[PubMed - indexed for MEDLINE]
3.

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VM, Trojanowski JQ.

Ann Neurol. 2007 May;61(5):427-34.

PMID:
17469116
[PubMed - indexed for MEDLINE]
4.

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

Volkening K, Leystra-Lantz C, Yang W, Jaffee H, Strong MJ.

Brain Res. 2009 Dec 11;1305:168-82. doi: 10.1016/j.brainres.2009.09.105. Epub 2009 Oct 6.

PMID:
19815002
[PubMed - indexed for MEDLINE]
5.

TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase.

Higashi S, Tsuchiya Y, Araki T, Wada K, Kabuta T.

Neurochem Int. 2010 Dec;57(8):906-13. doi: 10.1016/j.neuint.2010.09.010. Epub 2010 Oct 7.

PMID:
20933032
[PubMed - indexed for MEDLINE]
6.

TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.

Turner BJ, Bäumer D, Parkinson NJ, Scaber J, Ansorge O, Talbot K.

BMC Neurosci. 2008 Oct 28;9:104. doi: 10.1186/1471-2202-9-104.

PMID:
18957104
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis.

Bastow EL, Gourlay CW, Tuite MF.

Biochem Soc Trans. 2011 Oct;39(5):1482-7. doi: 10.1042/BST0391482. Review.

PMID:
21936838
[PubMed - indexed for MEDLINE]
8.

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

Crippa V, Sau D, Rusmini P, Boncoraglio A, Onesto E, Bolzoni E, Galbiati M, Fontana E, Marino M, Carra S, Bendotti C, De Biasi S, Poletti A.

Hum Mol Genet. 2010 Sep 1;19(17):3440-56. doi: 10.1093/hmg/ddq257. Epub 2010 Jun 22.

PMID:
20570967
[PubMed - indexed for MEDLINE]
Free Article
9.

Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.

Pokrishevsky E, Grad LI, Yousefi M, Wang J, Mackenzie IR, Cashman NR.

PLoS One. 2012;7(4):e35050. doi: 10.1371/journal.pone.0035050. Epub 2012 Apr 6.

PMID:
22493728
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation.

Tan CF, Eguchi H, Tagawa A, Onodera O, Iwasaki T, Tsujino A, Nishizawa M, Kakita A, Takahashi H.

Acta Neuropathol. 2007 May;113(5):535-42. Epub 2007 Feb 27.

PMID:
17333220
[PubMed - indexed for MEDLINE]
11.

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form.

Kerman A, Liu HN, Croul S, Bilbao J, Rogaeva E, Zinman L, Robertson J, Chakrabartty A.

Acta Neuropathol. 2010 Mar;119(3):335-44. doi: 10.1007/s00401-010-0646-5. Epub 2010 Jan 29.

PMID:
20111867
[PubMed - indexed for MEDLINE]
12.

Nuclear TAR DNA binding protein 43 expression in spinal cord neurons correlates with the clinical course in amyotrophic lateral sclerosis.

Sumi H, Kato S, Mochimaru Y, Fujimura H, Etoh M, Sakoda S.

J Neuropathol Exp Neurol. 2009 Jan;68(1):37-47. doi: 10.1097/NEN.0b013e3181919cb5.

PMID:
19104447
[PubMed - indexed for MEDLINE]
13.

TDP-43 in differential diagnosis of motor neuron disorders.

Dickson DW, Josephs KA, Amador-Ortiz C.

Acta Neuropathol. 2007 Jul;114(1):71-9. Epub 2007 Jun 14.

PMID:
17569066
[PubMed - indexed for MEDLINE]
14.

Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS.

Shan X, Vocadlo D, Krieger C.

Neurosci Lett. 2009 Jul 17;458(2):70-4. doi: 10.1016/j.neulet.2009.04.031. Epub 2009 Apr 18.

PMID:
19379791
[PubMed - indexed for MEDLINE]
15.

ALS pathogenesis: recent insights from genetics and mouse models.

Swarup V, Julien JP.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):363-9. doi: 10.1016/j.pnpbp.2010.08.006. Epub 2010 Aug 20.

PMID:
20728492
[PubMed - indexed for MEDLINE]
16.

SOD1 aggregation and ALS: role of metallation states and disulfide status.

Sheng Y, Chattopadhyay M, Whitelegge J, Valentine JS.

Curr Top Med Chem. 2012;12(22):2560-72. Review.

PMID:
23339308
[PubMed - indexed for MEDLINE]
17.

Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS.

Robertson J, Sanelli T, Xiao S, Yang W, Horne P, Hammond R, Pioro EP, Strong MJ.

Neurosci Lett. 2007 Jun 13;420(2):128-32. Epub 2007 Apr 8.

PMID:
17543992
[PubMed - indexed for MEDLINE]
18.

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.

Oh YK, Shin KS, Yuan J, Kang SJ.

J Neurochem. 2008 Feb;104(4):993-1005. doi: 10.1111/j.1471-4159.2007.05053.x.

PMID:
18233996
[PubMed - indexed for MEDLINE]
19.

The genetics and neuropathology of amyotrophic lateral sclerosis.

Al-Chalabi A, Jones A, Troakes C, King A, Al-Sarraj S, van den Berg LH.

Acta Neuropathol. 2012 Sep;124(3):339-52. doi: 10.1007/s00401-012-1022-4. Epub 2012 Aug 2. Review.

PMID:
22903397
[PubMed - indexed for MEDLINE]
20.

Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism.

Keller BA, Volkening K, Droppelmann CA, Ang LC, Rademakers R, Strong MJ.

Acta Neuropathol. 2012 Nov;124(5):733-47. doi: 10.1007/s00401-012-1035-z. Epub 2012 Sep 1.

PMID:
22941224
[PubMed - indexed for MEDLINE]

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