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Results: 1 to 20 of 145

1.

Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs.

Parrish AR, She X, Xiang Z, Coin I, Shen Z, Briggs SP, Dillin A, Wang L.

ACS Chem Biol. 2012 Jul 20;7(7):1292-302. doi: 10.1021/cb200542j. Epub 2012 May 11.

PMID:
22554080
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome.

Neumann H, Wang K, Davis L, Garcia-Alai M, Chin JW.

Nature. 2010 Mar 18;464(7287):441-4. doi: 10.1038/nature08817. Epub 2010 Feb 14.

PMID:
20154731
[PubMed - indexed for MEDLINE]
3.
4.

Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli.

Chatterjee A, Xiao H, Schultz PG.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14841-6. doi: 10.1073/pnas.1212454109. Epub 2012 Aug 27.

PMID:
22927411
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

An expanded genetic code with a functional quadruplet codon.

Anderson JC, Wu N, Santoro SW, Lakshman V, King DS, Schultz PG.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7566-71. Epub 2004 May 11.

PMID:
15138302
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A general approach for the generation of orthogonal tRNAs.

Wang L, Schultz PG.

Chem Biol. 2001 Sep;8(9):883-90.

PMID:
11564556
[PubMed - indexed for MEDLINE]
Free Article
7.

Performance analysis of orthogonal pairs designed for an expanded eukaryotic genetic code.

Nehring S, Budisa N, Wiltschi B.

PLoS One. 2012;7(4):e31992. doi: 10.1371/journal.pone.0031992. Epub 2012 Apr 6.

PMID:
22493661
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

De novo generation of mutually orthogonal aminoacyl-tRNA synthetase/tRNA pairs.

Neumann H, Slusarczyk AL, Chin JW.

J Am Chem Soc. 2010 Feb 24;132(7):2142-4. doi: 10.1021/ja9068722.

PMID:
20121121
[PubMed - indexed for MEDLINE]
9.

Engineering of an orthogonal aminoacyl-tRNA synthetase for efficient incorporation of the non-natural amino acid O-methyl-L-tyrosine using fluorescence-based bacterial cell sorting.

Kuhn SM, Rubini M, Fuhrmann M, Theobald I, Skerra A.

J Mol Biol. 2010 Nov 19;404(1):70-87. doi: 10.1016/j.jmb.2010.09.001. Epub 2010 Sep 15.

PMID:
20837025
[PubMed - indexed for MEDLINE]
10.

Transforming a pair of orthogonal tRNA-aminoacyl-tRNA synthetase from Archaea to function in mammalian cells.

Thibodeaux GN, Liang X, Moncivais K, Umeda A, Singer O, Alfonta L, Zhang ZJ.

PLoS One. 2010 Jun 22;5(6):e11263. doi: 10.1371/journal.pone.0011263.

PMID:
20582317
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.

Wan W, Tharp JM, Liu WR.

Biochim Biophys Acta. 2014 Jun;1844(6):1059-70. doi: 10.1016/j.bbapap.2014.03.002. Epub 2014 Mar 12. Review.

PMID:
24631543
[PubMed - indexed for MEDLINE]
12.

High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites.

Ozawa K, Loscha KV, Kuppan KV, Loh CT, Dixon NE, Otting G.

Biochem Biophys Res Commun. 2012 Feb 24;418(4):652-6. doi: 10.1016/j.bbrc.2012.01.069. Epub 2012 Jan 24.

PMID:
22293204
[PubMed - indexed for MEDLINE]
13.

An expanding genetic code.

Xie J, Schultz PG.

Methods. 2005 Jul;36(3):227-38. Review.

PMID:
16076448
[PubMed - indexed for MEDLINE]
14.

Generating permissive site-specific unnatural aminoacyl-tRNA synthetases.

Miyake-Stoner SJ, Refakis CA, Hammill JT, Lusic H, Hazen JL, Deiters A, Mehl RA.

Biochemistry. 2010 Mar 2;49(8):1667-77. doi: 10.1021/bi901947r.

PMID:
20082521
[PubMed - indexed for MEDLINE]
15.

Reprogramming the amino-acid substrate specificity of orthogonal aminoacyl-tRNA synthetases to expand the genetic code of eukaryotic cells.

Cropp TA, Anderson JC, Chin JW.

Nat Protoc. 2007;2(10):2590-600.

PMID:
17948002
[PubMed - indexed for MEDLINE]
16.

A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli.

Chatterjee A, Sun SB, Furman JL, Xiao H, Schultz PG.

Biochemistry. 2013 Mar 12;52(10):1828-37. doi: 10.1021/bi4000244. Epub 2013 Feb 27.

PMID:
23379331
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair.

Hancock SM, Uprety R, Deiters A, Chin JW.

J Am Chem Soc. 2010 Oct 27;132(42):14819-24. doi: 10.1021/ja104609m.

PMID:
20925334
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

Young DD, Young TS, Jahnz M, Ahmad I, Spraggon G, Schultz PG.

Biochemistry. 2011 Mar 22;50(11):1894-900. doi: 10.1021/bi101929e. Epub 2011 Feb 1.

PMID:
21280675
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Crucial optimization of translational components towards efficient incorporation of unnatural amino acids into proteins in mammalian cells.

Xiang L, Moncivais K, Jiang F, Willams B, Alfonta L, Zhang ZJ.

PLoS One. 2013 Jul 12;8(7):e67333. doi: 10.1371/journal.pone.0067333. Print 2013.

PMID:
23874413
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: minimizing misacylation.

Rodriguez EA, Lester HA, Dougherty DA.

RNA. 2007 Oct;13(10):1703-14. Epub 2007 Aug 13.

PMID:
17698638
[PubMed - indexed for MEDLINE]
Free PMC Article

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