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Items: 1 to 20 of 80

1.

Runx1 deficiency in CD4+ T cells causes fatal autoimmune inflammatory lung disease due to spontaneous hyperactivation of cells.

Wong WF, Kohu K, Nakamura A, Ebina M, Kikuchi T, Tazawa R, Tanaka K, Kon S, Funaki T, Sugahara-Tobinai A, Looi CY, Endo S, Funayama R, Kurokawa M, Habu S, Ishii N, Fukumoto M, Nakata K, Takai T, Satake M.

J Immunol. 2012 Jun 1;188(11):5408-20. doi: 10.4049/jimmunol.1102991. Epub 2012 May 2.

2.

The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.

Wong WF, Kohu K, Nagashima T, Funayama R, Matsumoto M, Movahed E, Tan GM, Yeow TC, Looi CY, Kurokawa M, Osato M, Igarashi K, Nakayama K, Satake M.

Mol Immunol. 2015 Dec;68(2 Pt A):223-33. doi: 10.1016/j.molimm.2015.08.012. Epub 2015 Sep 5.

PMID:
26350416
3.

Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation.

Gereke M, Gröbe L, Prettin S, Kasper M, Deppenmeier S, Gruber AD, Enelow RI, Buer J, Bruder D.

Respir Res. 2007 Jul 4;8:47.

4.

Down-regulation of Runx1 expression by TCR signal involves an autoregulatory mechanism and contributes to IL-2 production.

Wong WF, Kurokawa M, Satake M, Kohu K.

J Biol Chem. 2011 Apr 1;286(13):11110-8. doi: 10.1074/jbc.M110.166694. Epub 2011 Feb 3.

5.
6.

TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease.

Chiffoleau E, Kobayashi T, Walsh MC, King CG, Walsh PT, Hancock WW, Choi Y, Turka LA.

J Immunol. 2003 Dec 1;171(11):5751-9.

7.

Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases.

Murata K, Nose M, Ndhlovu LC, Sato T, Sugamura K, Ishii N.

J Immunol. 2002 Oct 15;169(8):4628-36.

8.

Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation.

Lippert E, Yowe DL, Gonzalo JA, Justice JP, Webster JM, Fedyk ER, Hodge M, Miller C, Gutierrez-Ramos JC, Borrego F, Keane-Myers A, Druey KM.

J Immunol. 2003 Aug 1;171(3):1542-55.

10.

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells.

Klunker S, Chong MM, Mantel PY, Palomares O, Bassin C, Ziegler M, Rückert B, Meiler F, Akdis M, Littman DR, Akdis CA.

J Exp Med. 2009 Nov 23;206(12):2701-15. doi: 10.1084/jem.20090596. Epub 2009 Nov 16.

14.

A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance.

Ishikawa S, Akakura S, Abe M, Terashima K, Chijiiwa K, Nishimura H, Hirose S, Shirai T.

J Immunol. 1998 Aug 1;161(3):1267-73.

15.

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.

Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL.

J Immunol. 2006 Jun 1;176(11):7062-70.

17.

Invariant NKT cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation.

Oh K, Byoun OJ, Ham DI, Kim YS, Lee DS.

Eur J Immunol. 2011 Feb;41(2):392-402. doi: 10.1002/eji.201040569. Epub 2010 Dec 29.

18.

Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

Lalor SJ, Dungan LS, Sutton CE, Basdeo SA, Fletcher JM, Mills KH.

J Immunol. 2011 May 15;186(10):5738-48. doi: 10.4049/jimmunol.1003597. Epub 2011 Apr 6.

19.

The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression.

Komine O, Hayashi K, Natsume W, Watanabe T, Seki Y, Seki N, Yagi R, Sukzuki W, Tamauchi H, Hozumi K, Habu S, Kubo M, Satake M.

J Exp Med. 2003 Jul 7;198(1):51-61. Epub 2003 Jun 30.

20.
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