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Results: 1 to 20 of 98

1.

Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity.

Bhattacharya P, Keating AF.

Toxicol Appl Pharmacol. 2012 Jun 15;261(3):227-35. doi: 10.1016/j.taap.2012.04.009. Epub 2012 Apr 13. Review.

PMID:
22531813
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Ovarian metabolism of xenobiotics.

Bhattacharya P, Keating AF.

Exp Biol Med (Maywood). 2011 Jul;236(7):765-71. doi: 10.1258/ebm.2011.011051. Epub 2011 May 26. Review.

PMID:
21616964
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility.

Sobinoff AP, Pye V, Nixon B, Roman SD, McLaughlin EA.

Toxicol Sci. 2010 Dec;118(2):653-66. doi: 10.1093/toxsci/kfq272. Epub 2010 Sep 9.

PMID:
20829426
[PubMed - indexed for MEDLINE]
Free Article
4.

Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries.

Keating AF, J Mark C, Sen N, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 2009 Dec 1;241(2):127-34. doi: 10.1016/j.taap.2009.08.012. Epub 2009 Aug 18.

PMID:
19695275
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model.

Hoyer PB, Devine PJ, Hu X, Thompson KE, Sipes IG.

Toxicol Pathol. 2001 Jan-Feb;29(1):91-9. Review.

PMID:
11215690
[PubMed - indexed for MEDLINE]
Free Article
6.

Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.

Borman SM, Christian PJ, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 2000 Sep 15;167(3):191-8.

PMID:
10986010
[PubMed - indexed for MEDLINE]
7.

Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study.

Hoyer PB, Sipes IG.

Birth Defects Res B Dev Reprod Toxicol. 2007 Apr;80(2):113-25. Review.

PMID:
17342769
[PubMed - indexed for MEDLINE]
8.

involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene.

Rajapaksa KS, Sipes IG, Hoyer PB.

Toxicol Sci. 2007 Apr;96(2):327-34. Epub 2007 Jan 4.

PMID:
17204581
[PubMed - indexed for MEDLINE]
Free Article
9.

Understanding the Villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling.

Sobinoff AP, Mahony M, Nixon B, Roman SD, McLaughlin EA.

Toxicol Sci. 2011 Oct;123(2):563-75. doi: 10.1093/toxsci/kfr195. Epub 2011 Jul 23.

PMID:
21785161
[PubMed - indexed for MEDLINE]
Free Article
10.

Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure.

Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB.

Toxicol Sci. 2008 Oct;105(2):351-9. doi: 10.1093/toxsci/kfn136. Epub 2008 Jul 12.

PMID:
18622027
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Xenobiotic effects on ovarian preantral follicles.

Mark-Kappeler CJ, Hoyer PB, Devine PJ.

Biol Reprod. 2011 Nov;85(5):871-83. doi: 10.1095/biolreprod.111.091173. Epub 2011 Jun 22. Review.

PMID:
21697514
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity.

Mark-Kappeler CJ, Sen N, Keating AF, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 2010 Nov 15;249(1):1-7. doi: 10.1016/j.taap.2010.08.024. Epub 2010 Sep 9.

PMID:
20816688
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary.

Uzumcu M, Kuhn PE, Marano JE, Armenti AE, Passantino L.

J Endocrinol. 2006 Dec;191(3):549-58.

PMID:
17170213
[PubMed - indexed for MEDLINE]
Free Article
14.

Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.

Springer LN, McAsey ME, Flaws JA, Tilly JL, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 1996 Aug;139(2):394-401.

PMID:
8806857
[PubMed - indexed for MEDLINE]
15.

Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.

Mark-Kappeler CJ, Sen N, Lukefahr A, McKee L, Sipes IG, Konhilas J, Hoyer PB.

Biol Reprod. 2011 Oct;85(4):755-62. doi: 10.1095/biolreprod.111.092742. Epub 2011 Jun 15.

PMID:
21677306
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity.

Kappeler CJ, Hoyer PB.

Syst Biol Reprod Med. 2012 Feb;58(1):57-62. doi: 10.3109/19396368.2011.648820. Review.

PMID:
22239082
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Assessment of follicle destruction in chemical-induced ovarian toxicity.

Hoyer PB, Sipes IG.

Annu Rev Pharmacol Toxicol. 1996;36:307-31. Review.

PMID:
8725392
[PubMed - indexed for MEDLINE]
18.

Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice.

Kao SW, Sipes IG, Hoyer PB.

Reprod Toxicol. 1999 Jan-Feb;13(1):67-75.

PMID:
10080302
[PubMed - indexed for MEDLINE]
19.

Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system.

Igawa Y, Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB.

Toxicol Appl Pharmacol. 2009 Feb 1;234(3):361-9. doi: 10.1016/j.taap.2008.10.009. Epub 2008 Nov 5.

PMID:
19027032
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss.

Thompson KE, Bourguet SM, Christian PJ, Benedict JC, Sipes IG, Flaws JA, Hoyer PB.

Toxicol Appl Pharmacol. 2005 Mar 1;203(2):114-23.

PMID:
15710172
[PubMed - indexed for MEDLINE]

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