Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 83

Related Citations for PubMed (Select 22517326)


The ancient drug salicylate directly activates AMP-activated protein kinase.

Hawley SA, Fullerton MD, Ross FA, Schertzer JD, Chevtzoff C, Walker KJ, Peggie MW, Zibrova D, Green KA, Mustard KJ, Kemp BE, Sakamoto K, Steinberg GR, Hardie DG.

Science. 2012 May 18;336(6083):918-22. doi: 10.1126/science.1215327. Epub 2012 Apr 19.


Salsalate and adiponectin ameliorate hepatic steatosis by inhibition of the hepatokine fetuin-A.

Jung TW, Youn BS, Choi HY, Lee SY, Hong HC, Yang SJ, Yoo HJ, Kim BH, Baik SH, Choi KM.

Biochem Pharmacol. 2013 Oct 1;86(7):960-9. doi: 10.1016/j.bcp.2013.07.034. Epub 2013 Aug 13.


Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

Göransson O, McBride A, Hawley SA, Ross FA, Shpiro N, Foretz M, Viollet B, Hardie DG, Sakamoto K.

J Biol Chem. 2007 Nov 9;282(45):32549-60. Epub 2007 Sep 12.


AMPK: mediating the metabolic effects of salicylate-based drugs?

Steinberg GR, Dandapani M, Hardie DG.

Trends Endocrinol Metab. 2013 Oct;24(10):481-7. doi: 10.1016/j.tem.2013.06.002. Epub 2013 Jul 19.


Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

Sanders MJ, Ali ZS, Hegarty BD, Heath R, Snowden MA, Carling D.

J Biol Chem. 2007 Nov 9;282(45):32539-48. Epub 2007 Aug 29.


AMP-activated protein kinase in metabolic control and insulin signaling.

Towler MC, Hardie DG.

Circ Res. 2007 Feb 16;100(3):328-41. Review.


AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.

Benziane B, Björnholm M, Lantier L, Viollet B, Zierath JR, Chibalin AV.

Am J Physiol Cell Physiol. 2009 Dec;297(6):C1554-66. doi: 10.1152/ajpcell.00010.2009. Epub 2009 Oct 14.


AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.

Bultot L, Guigas B, Von Wilamowitz-Moellendorff A, Maisin L, Vertommen D, Hussain N, Beullens M, Guinovart JJ, Foretz M, Viollet B, Sakamoto K, Hue L, Rider MH.

Biochem J. 2012 Apr 1;443(1):193-203. doi: 10.1042/BJ20112026.


Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

Scott JW, van Denderen BJ, Jorgensen SB, Honeyman JE, Steinberg GR, Oakhill JS, Iseli TJ, Koay A, Gooley PR, Stapleton D, Kemp BE.

Chem Biol. 2008 Nov 24;15(11):1220-30. doi: 10.1016/j.chembiol.2008.10.005.


Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.

Benziane B, Björnholm M, Pirkmajer S, Austin RL, Kotova O, Viollet B, Zierath JR, Chibalin AV.

J Biol Chem. 2012 Jul 6;287(28):23451-63. doi: 10.1074/jbc.M111.331926. Epub 2012 May 18.


A-769662 protects osteoblasts from hydrogen dioxide-induced apoptosis through activating of AMP-activated protein kinase (AMPK).

Zhu Y, Zhou J, Ao R, Yu B.

Int J Mol Sci. 2014 Jun 23;15(6):11190-203. doi: 10.3390/ijms150611190.


A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle.

Treebak JT, Birk JB, Hansen BF, Olsen GS, Wojtaszewski JF.

Am J Physiol Cell Physiol. 2009 Oct;297(4):C1041-52. doi: 10.1152/ajpcell.00051.2009. Epub 2009 Aug 5.


AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism.

Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS.

J Lipid Res. 2013 Jan;54(1):134-51. doi: 10.1194/jlr.M030528. Epub 2012 Nov 1.


Licochalcone A regulates hepatic lipid metabolism through activation of AMP-activated protein kinase.

Quan HY, Kim SJ, Kim do Y, Jo HK, Kim GW, Chung SH.

Fitoterapia. 2013 Apr;86:208-16. doi: 10.1016/j.fitote.2013.03.005. Epub 2013 Mar 14.


Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice.

Li YY, Yu LF, Zhang LN, Qiu BY, Su MB, Wu F, Chen DK, Pang T, Gu M, Zhang W, Ma WP, Jiang HW, Li JY, Nan FJ, Li J.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):325-34. doi: 10.1016/j.taap.2013.09.006. Epub 2013 Sep 18.


Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R, Zhao G, Marsh K, Kym P, Jung P, Camp HS, Frevert E.

Cell Metab. 2006 Jun;3(6):403-16.


α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase.

Chen WL, Kang CH, Wang SG, Lee HM.

Diabetologia. 2012 Jun;55(6):1824-35. doi: 10.1007/s00125-012-2530-4. Epub 2012 Mar 30.


Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK-mTOR-SREBP signaling pathway.

Quan HY, Kim do Y, Kim SJ, Jo HK, Kim GW, Chung SH.

Biochem Pharmacol. 2013 May 1;85(9):1330-40. doi: 10.1016/j.bcp.2013.02.007. Epub 2013 Feb 19.


Purple sweet potato anthocyanins attenuate hepatic lipid accumulation through activating adenosine monophosphate-activated protein kinase in human HepG2 cells and obese mice.

Hwang YP, Choi JH, Han EH, Kim HG, Wee JH, Jung KO, Jung KH, Kwon KI, Jeong TC, Chung YC, Jeong HG.

Nutr Res. 2011 Dec;31(12):896-906. doi: 10.1016/j.nutres.2011.09.026.


Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase.

Rajamohan F, Harris MS, Frisbie RK, Hoth LR, Geoghegan KF, Valentine JJ, Reyes AR, Landro JA, Qiu X, Kurumbail RG.

Protein Expr Purif. 2010 Oct;73(2):189-97. doi: 10.1016/j.pep.2010.04.022. Epub 2010 May 6.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk