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Results: 1 to 20 of 140

1.

In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.

Kitchen SG, Levin BR, Bristol G, Rezek V, Kim S, Aguilera-Sandoval C, Balamurugan A, Yang OO, Zack JA.

PLoS Pathog. 2012;8(4):e1002649. doi: 10.1371/journal.ppat.1002649. Epub 2012 Apr 12.

PMID:
22511873
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

Kitchen SG, Bennett M, Galić Z, Kim J, Xu Q, Young A, Lieberman A, Joseph A, Goldstein H, Ng H, Yang O, Zack JA.

PLoS One. 2009 Dec 7;4(12):e8208. doi: 10.1371/journal.pone.0008208.

PMID:
19997617
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Limited transplantation of antigen-expressing hematopoietic stem cells induces long-lasting cytotoxic T cell responses.

Denning WL, Xu J, Guo S, Klug CA, Hel Z.

PLoS One. 2011 Feb 17;6(2):e16897. doi: 10.1371/journal.pone.0016897.

PMID:
21379572
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.

Ringpis GE, Shimizu S, Arokium H, Camba-Colón J, Carroll MV, Cortado R, Xie Y, Kim PY, Sahakyan A, Lowe EL, Narukawa M, Kandarian FN, Burke BP, Symonds GP, An DS, Chen IS, Kamata M.

PLoS One. 2012;7(12):e53492. doi: 10.1371/journal.pone.0053492. Epub 2012 Dec 31.

PMID:
23300932
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.

Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H.

J Virol. 2008 Mar;82(6):3078-89. doi: 10.1128/JVI.01812-07. Epub 2008 Jan 9.

PMID:
18184707
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.

Giannoni F, Hardee CL, Wherley J, Gschweng E, Senadheera S, Kaufman ML, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte ON, Economou JS, Ribas A, Kohn DB.

Mol Ther. 2013 May;21(5):1044-54. doi: 10.1038/mt.2013.8. Epub 2013 Feb 5.

PMID:
23380815
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity.

Ha SP, Klemen ND, Kinnebrew GH, Brandmaier AG, Marsh J, Hangoc G, Palmer DC, Restifo NP, Cornetta K, Broxmeyer HE, Touloukian CE.

J Clin Invest. 2010 Dec;120(12):4273-88. doi: 10.1172/JCI43274. Epub 2010 Nov 15.

PMID:
21084750
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

IL-7 enhancement of antigen-driven activation/expansion of HIV-1-specific cytotoxic T lymphocyte precursors (CTLp).

Ferrari G, King K, Rathbun K, Place CA, Packard MV, Bartlett JA, Bolognesi DP, Weinhold KJ.

Clin Exp Immunol. 1995 Aug;101(2):239-48.

PMID:
7544247
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

Kalams SA, Johnson RP, Trocha AK, Dynan MJ, Ngo HS, D'Aquila RT, Kurnick JT, Walker BD.

J Exp Med. 1994 Apr 1;179(4):1261-71.

PMID:
8145043
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Potential use of T cell receptor genes to modify hematopoietic stem cells for the gene therapy of cancer.

Clay TM, Custer MC, Spiess PJ, Nishimura MI.

Pathol Oncol Res. 1999;5(1):3-15. Review.

PMID:
10079371
[PubMed - indexed for MEDLINE]
Free Article
13.

A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells.

Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, Gras S, Chikata T, Kuse N, Fastenackels S, Gostick E, Bridgeman JS, Venturi V, Arkoub ZA, Agut H, van Bockel DJ, Almeida JR, Douek DC, Meyer L, Venet A, Takiguchi M, Rossjohn J, Price DA, Appay V.

Immunity. 2013 Mar 21;38(3):425-36. doi: 10.1016/j.immuni.2012.11.021.

PMID:
23521884
[PubMed - indexed for MEDLINE]
Free Article
14.

RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication.

Bonyhadi ML, Moss K, Voytovich A, Auten J, Kalfoglou C, Plavec I, Forestell S, Su L, Böhnlein E, Kaneshima H.

J Virol. 1997 Jun;71(6):4707-16.

PMID:
9151864
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Functional and genetic integrity of the CD8 T-cell repertoire in advanced HIV infection.

Gamberg JC, Bowmer MI, Trahey JC, Campbell CM, Pardoe I, Grant MD.

AIDS. 1999 Oct 22;13(15):2043-53.

PMID:
10546856
[PubMed - indexed for MEDLINE]
16.
17.

Novel CD8+ T cell-based vaccine stimulates Gp120-specific CTL responses leading to therapeutic and long-term immunity in transgenic HLA-A2 mice.

Nanjundappa RH, Wang R, Xie Y, Umeshappa CS, Xiang J.

Vaccine. 2012 May 21;30(24):3519-25. doi: 10.1016/j.vaccine.2012.03.075. Epub 2012 Apr 6.

PMID:
22484292
[PubMed - indexed for MEDLINE]
18.

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.

Walker JE, Chen RX, McGee J, Nacey C, Pollard RB, Abedi M, Bauer G, Nolta JA, Anderson JS.

J Virol. 2012 May;86(10):5719-29. doi: 10.1128/JVI.06300-11. Epub 2012 Mar 7.

PMID:
22398281
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Poor HIV control in HLA-B*27 and B*57/58 noncontrollers is associated with limited number of polyfunctional Gag p24-specific CD8+ T cells.

Techakriengkrai N, Tansiri Y, Hansasuta P.

AIDS. 2013 Jan 2;27(1):17-27. doi: 10.1097/QAD.0b013e32835ac0e1.

PMID:
23079801
[PubMed - indexed for MEDLINE]
20.

Narrowed TCR diversity for immunised mice challenged with recombinant influenza A-HIV Env(311-320) virus.

Cukalac T, Moffat JM, Venturi V, Davenport MP, Doherty PC, Turner SJ, Stambas J.

Vaccine. 2009 Nov 12;27(48):6755-61. doi: 10.1016/j.vaccine.2009.08.079. Epub 2009 Sep 8.

PMID:
19744584
[PubMed - indexed for MEDLINE]

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