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Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni.

Ingram JR, Rafi SB, Eroy-Reveles AA, Ray M, Lambeth L, Hsieh I, Ruelas D, Lim KC, Sakanari J, Craik CS, Jacobson MP, McKerrow JH.

PLoS Negl Trop Dis. 2012;6(4):e1589. doi: 10.1371/journal.pntd.0001589. Epub 2012 Apr 3.


Cercarial elastase is encoded by a functionally conserved gene family across multiple species of schistosomes.

Salter JP, Choe Y, Albrecht H, Franklin C, Lim KC, Craik CS, McKerrow JH.

J Biol Chem. 2002 Jul 5;277(27):24618-24. Epub 2002 May 1.


The Schistosomatium douthitti cercarial elastase is biochemically and structurally distinct from that of Schistosoma mansoni.

Amiri P, Sakanari J, Basch P, Newport G, McKerrow JH.

Mol Biochem Parasitol. 1988 Mar;28(2):113-20.


Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes.

Ingram J, Knudsen G, Lim KC, Hansell E, Sakanari J, McKerrow J.

PLoS Negl Trop Dis. 2011 Sep;5(9):e1337. doi: 10.1371/journal.pntd.0001337. Epub 2011 Sep 27.


Schistosoma mansoni elastase: an immune target regulated during the parasite life-cycle.

Pierrot C, Godin C, Liu JL, Capron A, Khalife J.

Parasitology. 1996 Dec;113 ( Pt 6):519-26.


Evolutionary histories of expanded peptidase families in Schistosoma mansoni.

Silva LL, Marcet-Houben M, Zerlotini A, Gabaldón T, Oliveira G, Nahum LA.

Mem Inst Oswaldo Cruz. 2011 Nov;106(7):864-77.


Cloning and characterization of two genes encoding Schistosoma mansoni elastase.

Pierrot C, Capron A, Khalife J.

Mol Biochem Parasitol. 1995 Dec;75(1):113-7. No abstract available.


Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry.

Curwen RS, Ashton PD, Sundaralingam S, Wilson RA.

Mol Cell Proteomics. 2006 May;5(5):835-44. Epub 2006 Feb 9.


SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.

Dvorák J, Mashiyama ST, Sajid M, Braschi S, Delcroix M, Schneider EL, McKerrow WH, Bahgat M, Hansell E, Babbitt PC, Craik CS, McKerrow JH, Caffrey CR.

PLoS Negl Trop Dis. 2009 Jun 2;3(6):e449. doi: 10.1371/journal.pntd.0000449.


The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti.

Dolecková K, Kasný M, Mikes L, Cartwright J, Jedelský P, Schneider EL, Dvorák J, Mountford AP, Craik CS, Horák P.

Int J Parasitol. 2009 Jan;39(2):201-11. doi: 10.1016/j.ijpara.2008.06.010. Epub 2008 Jul 26.


Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.

Horn M, Fajtová P, Rojo Arreola L, Ulrychová L, Bartošová-Sojková P, Franta Z, Protasio AV, Opavský D, Vondrášek J, McKerrow JH, Mareš M, Caffrey CR, Dvořák J.

PLoS Negl Trop Dis. 2014 Mar 27;8(3):e2766. doi: 10.1371/journal.pntd.0002766. eCollection 2014 Mar.


A blood fluke serine protease inhibitor regulates an endogenous larval elastase.

Quezada LA, Sajid M, Lim KC, McKerrow JH.

J Biol Chem. 2012 Mar 2;287(10):7074-83. doi: 10.1074/jbc.M111.313304. Epub 2011 Dec 15.


Schistosoma japonicum reveals distinct reactivity with antisera directed to proteases mediating host infection and invasion by cercariae of S. mansoni or S. haematobium.

Chlichlia K, Schauwienold B, Kirsten C, Doenhoff MJ, Fishelson Z, Ruppel A.

Parasite Immunol. 2005 Mar;27(3):97-102.


A cyclohexanecarboxamide derivative with inhibitory effects on Schistosoma mansoni cercarial serine protease and penetration of mice skin by the parasite.

Bahgat M, Aboul-Enein MN, El Azzouny AA, Maghraby A, Ruppel A, Soliman WM.

Acta Pol Pharm. 2009 May-Jun;66(3):333-40.


Cleavage of human IgE mediated by Schistosoma mansoni.

Pleass RJ, Kusel JR, Woof JM.

Int Arch Allergy Immunol. 2000 Mar;121(3):194-204.


Proteomic analysis of skin invasion by blood fluke larvae.

Hansell E, Braschi S, Medzihradszky KF, Sajid M, Debnath M, Ingram J, Lim KC, McKerrow JH.

PLoS Negl Trop Dis. 2008 Jul 16;2(7):e262. doi: 10.1371/journal.pntd.0000262.


Characterization of phosphodiesterase-5 as a surface protein in the tegument of Schistosoma mansoni.

Rofatto HK, Tararam CA, Borges WC, Wilson RA, Leite LC, Farias LP.

Mol Biochem Parasitol. 2009 Jul;166(1):32-41. doi: 10.1016/j.molbiopara.2009.02.006. Epub 2009 Feb 24.


Molecular characterization of SUMO E2 conjugation enzyme: differential expression profile in Schistosoma mansoni.

Pereira RV, Cabral FJ, Gomes MS, Baba EH, Jannotti-Passos LK, Carvalho O, Rodrigues V, Afonso RJ, Castro-Borges W, Guerra-Sá R.

Parasitol Res. 2011 Dec;109(6):1537-46. doi: 10.1007/s00436-011-2394-4. Epub 2011 May 15.

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