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Items: 1 to 20 of 100

1.

Fabs enable single particle cryoEM studies of small proteins.

Wu S, Avila-Sakar A, Kim J, Booth DS, Greenberg CH, Rossi A, Liao M, Li X, Alian A, Griner SL, Juge N, Yu Y, Mergel CM, Chaparro-Riggers J, Strop P, Tampé R, Edwards RH, Stroud RM, Craik CS, Cheng Y.

Structure. 2012 Apr 4;20(4):582-92. doi: 10.1016/j.str.2012.02.017. Epub 2012 Apr 3.

2.

Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.

Zhang Y, Eigenbrot C, Zhou L, Shia S, Li W, Quan C, Tom J, Moran P, Di Lello P, Skelton NJ, Kong-Beltran M, Peterson A, Kirchhofer D.

J Biol Chem. 2014 Jan 10;289(2):942-55. doi: 10.1074/jbc.M113.514067. Epub 2013 Nov 13.

3.

An antibody against the C-terminal domain of PCSK9 lowers LDL cholesterol levels in vivo.

Schiele F, Park J, Redemann N, Luippold G, Nar H.

J Mol Biol. 2014 Feb 20;426(4):843-52. doi: 10.1016/j.jmb.2013.11.011. Epub 2013 Nov 16.

PMID:
24252255
4.

The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.

Ciferri C, Lipari MT, Liang WC, Estevez A, Hang J, Stawicki S, Wu Y, Moran P, Elliott M, Eigenbrot C, Katschke KJ, van Lookeren Campagne M, Kirchhofer D.

Biochem J. 2015 Dec 1;472(2):169-81. doi: 10.1042/BJ20150601. Epub 2015 Sep 18.

PMID:
26385991
5.

Multibranch and pseudopeptide approach for design of novel inhibitors of subtilisin kexin isozyme-1.

Basak S, Mohottalage D, Basak A.

Protein Pept Lett. 2006;13(9):863-76.

PMID:
17100641
6.

Structural basis for intramembrane proteolysis by rhomboid serine proteases.

Ben-Shem A, Fass D, Bibi E.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):462-6. Epub 2006 Dec 26.

7.

Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides.

Morgan DJ, Sazanov LA.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):711-8. doi: 10.1016/j.bbabio.2008.03.023. Epub 2008 Apr 3.

8.

An improved single-chain Fab platform for efficient display and recombinant expression.

Koerber JT, Hornsby MJ, Wells JA.

J Mol Biol. 2015 Jan 30;427(2):576-86. doi: 10.1016/j.jmb.2014.11.017. Epub 2014 Dec 3.

9.

A reverse binding motif that contributes to specific protease inhibition by antibodies.

Schneider EL, Lee MS, Baharuddin A, Goetz DH, Farady CJ, Ward M, Wang CI, Craik CS.

J Mol Biol. 2012 Jan 27;415(4):699-715. doi: 10.1016/j.jmb.2011.11.036. Epub 2011 Nov 27.

10.

Automated cryoEM data acquisition and analysis of 284742 particles of GroEL.

Stagg SM, Lander GC, Pulokas J, Fellmann D, Cheng A, Quispe JD, Mallick SP, Avila RM, Carragher B, Potter CS.

J Struct Biol. 2006 Sep;155(3):470-81. Epub 2006 May 22.

PMID:
16762565
11.

Antibody Fab display and selection through fusion to the pIX coat protein of filamentous phage.

Tornetta M, Baker S, Whitaker B, Lu J, Chen Q, Pisors E, Shi L, Luo J, Sweet R, Tsui P.

J Immunol Methods. 2010 Aug 31;360(1-2):39-46. doi: 10.1016/j.jim.2010.06.001. Epub 2010 Jun 17.

PMID:
20600082
12.

Generation of Fab fragment-like molecular recognition proteins against staphylococcal enterotoxin B by phage display technology.

Urushibata Y, Itoh K, Ohshima M, Seto Y.

Clin Vaccine Immunol. 2010 Nov;17(11):1708-17. doi: 10.1128/CVI.00229-10. Epub 2010 Sep 15.

13.

The role of the L2 loop in the regulation and maintaining the proteolytic activity of HtrA (DegP) protein from Escherichia coli.

Sobiecka-Szkatula A, Gieldon A, Scire A, Tanfani F, Figaj D, Koper T, Ciarkowski J, Lipinska B, Skorko-Glonek J.

Arch Biochem Biophys. 2010 Aug 15;500(2):123-30. doi: 10.1016/j.abb.2010.05.028. Epub 2010 May 31.

PMID:
20515644
14.

Improved Fab presentation on phage surface with the use of molecular chaperone coplasmid system.

Loh Q, Leong SW, Tye GJ, Choong YS, Lim TS.

Anal Biochem. 2015 May 15;477:56-61. doi: 10.1016/j.ab.2015.02.026. Epub 2015 Mar 10.

PMID:
25769419
15.

The structure of human tripeptidyl peptidase II as determined by a hybrid approach.

Schönegge AM, Villa E, Förster F, Hegerl R, Peters J, Baumeister W, Rockel B.

Structure. 2012 Apr 4;20(4):593-603. doi: 10.1016/j.str.2012.01.025. Epub 2012 Apr 3.

16.

CryoEM and image sorting for flexible protein/DNA complexes.

Villarreal SA, Stewart PL.

J Struct Biol. 2014 Jul;187(1):76-83. doi: 10.1016/j.jsb.2013.12.002. Epub 2013 Dec 9.

PMID:
24333094
17.

Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition.

Farady CJ, Egea PF, Schneider EL, Darragh MR, Craik CS.

J Mol Biol. 2008 Jul 4;380(2):351-60. doi: 10.1016/j.jmb.2008.05.009. Epub 2008 May 11.

18.

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy.

Chen S, McMullan G, Faruqi AR, Murshudov GN, Short JM, Scheres SH, Henderson R.

Ultramicroscopy. 2013 Dec;135:24-35. doi: 10.1016/j.ultramic.2013.06.004. Epub 2013 Jun 21.

19.

2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy.

Campbell MG, Veesler D, Cheng A, Potter CS, Carragher B.

Elife. 2015 Mar 11;4. doi: 10.7554/eLife.06380.

20.

Neutralizing human Fab fragments against measles virus recovered by phage display.

de Carvalho Nicacio C, Williamson RA, Parren PW, Lundkvist A, Burton DR, Björling E.

J Virol. 2002 Jan;76(1):251-8.

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