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Results: 1 to 20 of 131

Similar articles for PubMed (Select 22451913)

1.

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PØ, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. doi: 10.1073/pnas.1121623109. Epub 2012 Mar 26.

2.

The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target.

Barclay AN, Van den Berg TK.

Annu Rev Immunol. 2014;32:25-50. doi: 10.1146/annurev-immunol-032713-120142. Epub 2013 Nov 6. Review.

PMID:
24215318
3.

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K.

Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20.

PMID:
24269920
4.

CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.

Zhao XW, van Beek EM, Schornagel K, Van der Maaden H, Van Houdt M, Otten MA, Finetti P, Van Egmond M, Matozaki T, Kraal G, Birnbaum D, van Elsas A, Kuijpers TW, Bertucci F, van den Berg TK.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18342-7. doi: 10.1073/pnas.1106550108. Epub 2011 Oct 31.

5.

Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.

Ide K, Wang H, Tahara H, Liu J, Wang X, Asahara T, Sykes M, Yang YG, Ohdan H.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5062-6. Epub 2007 Mar 12.

6.

Novel CD47: SIRPα dependent mechanism for the activation of STAT3 in antigen-presenting cell.

Toledano N, Gur-Wahnon D, Ben-Yehuda A, Rachmilewitz J.

PLoS One. 2013 Sep 20;8(9):e75595. doi: 10.1371/journal.pone.0075595. eCollection 2013.

7.

Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway.

Matozaki T, Murata Y, Okazawa H, Ohnishi H.

Trends Cell Biol. 2009 Feb;19(2):72-80. doi: 10.1016/j.tcb.2008.12.001. Epub 2009 Jan 12. Review.

PMID:
19144521
8.

Soluble extracellular domains of human SIRPα and CD47 expressed in Escherichia coli enhances the phagocytosis of leukemia cells by macrophages in vitro.

Lin Y, Yan XQ, Yang F, Yang XW, Jiang X, Zhao XC, Zhu BK, Liu L, Qin HY, Liang YM, Han H.

Protein Expr Purif. 2012 Sep;85(1):109-16. doi: 10.1016/j.pep.2012.07.002. Epub 2012 Jul 17.

PMID:
22813925
9.

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

Theocharides AP, Jin L, Cheng PY, Prasolava TK, Malko AV, Ho JM, Poeppl AG, van Rooijen N, Minden MD, Danska JS, Dick JE, Wang JC.

J Exp Med. 2012 Sep 24;209(10):1883-99. Epub 2012 Sep 3.

10.

Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47.

Wang C, Wang H, Ide K, Wang Y, Van Rooijen N, Ohdan H, Yang YG.

Cell Transplant. 2011;20(11-12):1915-20. doi: 10.3727/096368911X566253. Epub 2011 Apr 29.

11.

The CD47 pathway is deregulated in human immune thrombocytopenia.

Catani L, Sollazzo D, Ricci F, Polverelli N, Palandri F, Baccarani M, Vianelli N, Lemoli RM.

Exp Hematol. 2011 Apr;39(4):486-94. doi: 10.1016/j.exphem.2010.12.011. Epub 2011 Jan 4.

PMID:
21211546
12.

The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications.

Chao MP, Weissman IL, Majeti R.

Curr Opin Immunol. 2012 Apr;24(2):225-32. doi: 10.1016/j.coi.2012.01.010. Epub 2012 Feb 4. Review.

13.

Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.

Tsai RK, Rodriguez PL, Discher DE.

Blood Cells Mol Dis. 2010 Jun 15;45(1):67-74. doi: 10.1016/j.bcmd.2010.02.016. Epub 2010 Mar 17.

14.

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.

Chao MP, Jaiswal S, Weissman-Tsukamoto R, Alizadeh AA, Gentles AJ, Volkmer J, Weiskopf K, Willingham SB, Raveh T, Park CY, Majeti R, Weissman IL.

Sci Transl Med. 2010 Dec 22;2(63):63ra94. doi: 10.1126/scitranslmed.3001375.

15.

Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells.

Kim D, Wang J, Willingham SB, Martin R, Wernig G, Weissman IL.

Leukemia. 2012 Dec;26(12):2538-45. doi: 10.1038/leu.2012.141. Epub 2012 May 30.

PMID:
22648449
16.

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies.

Weiskopf K, Ring AM, Ho CC, Volkmer JP, Levin AM, Volkmer AK, Ozkan E, Fernhoff NB, van de Rijn M, Weissman IL, Garcia KC.

Science. 2013 Jul 5;341(6141):88-91. doi: 10.1126/science.1238856. Epub 2013 May 30.

17.

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma.

Edris B, Weiskopf K, Volkmer AK, Volkmer JP, Willingham SB, Contreras-Trujillo H, Liu J, Majeti R, West RB, Fletcher JA, Beck AH, Weissman IL, van de Rijn M.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6656-61. doi: 10.1073/pnas.1121629109. Epub 2012 Mar 26.

18.

Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice.

Waern JM, Yuan Q, Rüdrich U, Becker PD, Schulze K, Strick-Marchand H, Huntington ND, Zacher BJ, Wursthorn K, DiSanto JP, Guzman CA, Manns MP, Ott M, Bock M.

Hepatology. 2012 Oct;56(4):1479-88. doi: 10.1002/hep.25816.

PMID:
22535707
19.

Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies.

Soto-Pantoja DR, Miller TW, Frazier WA, Roberts DD.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2842; author reply E2844-5. doi: 10.1073/pnas.1205441109. Epub 2012 Aug 24. No abstract available.

20.

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.

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