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Items: 1 to 20 of 184

1.

Signaling the mitochondrial unfolded protein response.

Pellegrino MW, Nargund AM, Haynes CM.

Biochim Biophys Acta. 2013 Feb;1833(2):410-6. doi: 10.1016/j.bbamcr.2012.02.019. Epub 2012 Mar 14. Review.

2.

The mitochondrial UPR - protecting organelle protein homeostasis.

Haynes CM, Ron D.

J Cell Sci. 2010 Nov 15;123(Pt 22):3849-55. doi: 10.1242/jcs.075119. Review.

3.

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans.

Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D.

Mol Cell. 2010 Feb 26;37(4):529-40. doi: 10.1016/j.molcel.2010.01.015.

4.

Surveillance-activated defenses block the ROS-induced mitochondrial unfolded protein response.

Runkel ED, Liu S, Baumeister R, Schulze E.

PLoS Genet. 2013;9(3):e1003346. doi: 10.1371/journal.pgen.1003346. Epub 2013 Mar 14.

5.

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.

Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D.

Dev Cell. 2007 Oct;13(4):467-80.

6.

Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response.

Benedetti C, Haynes CM, Yang Y, Harding HP, Ron D.

Genetics. 2006 Sep;174(1):229-39. Epub 2006 Jul 2.

7.

Mitochondria Retrograde Signaling and the UPR mt: Where Are We in Mammals?

Arnould T, Michel S, Renard P.

Int J Mol Sci. 2015 Aug 6;16(8):18224-51. doi: 10.3390/ijms160818224. Review.

8.

Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2.

Baker BM, Nargund AM, Sun T, Haynes CM.

PLoS Genet. 2012;8(6):e1002760. doi: 10.1371/journal.pgen.1002760. Epub 2012 Jun 14.

9.

The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?

Bennett CF, Kaeberlein M.

Exp Gerontol. 2014 Aug;56:142-6. doi: 10.1016/j.exger.2014.02.002. Epub 2014 Feb 8. Review.

10.

Chaperone-protease networks in mitochondrial protein homeostasis.

Voos W.

Biochim Biophys Acta. 2013 Feb;1833(2):388-99. doi: 10.1016/j.bbamcr.2012.06.005. Epub 2012 Jun 13. Review.

11.

Mitochondrial stress signaling: a pathway unfolds.

Broadley SA, Hartl FU.

Trends Cell Biol. 2008 Jan;18(1):1-4. Epub 2007 Dec 18.

PMID:
18068368
12.

Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt).

Nargund AM, Fiorese CJ, Pellegrino MW, Deng P, Haynes CM.

Mol Cell. 2015 Apr 2;58(1):123-33. doi: 10.1016/j.molcel.2015.02.008. Epub 2015 Mar 12.

13.

Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?

Hu F, Liu F.

Cell Signal. 2011 Oct;23(10):1528-33. doi: 10.1016/j.cellsig.2011.05.008. Epub 2011 May 15. Review.

14.

Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM.

Science. 2012 Aug 3;337(6094):587-90. doi: 10.1126/science.1223560. Epub 2012 Jun 14.

15.

The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism.

Lill R, Hoffmann B, Molik S, Pierik AJ, Rietzschel N, Stehling O, Uzarska MA, Webert H, Wilbrecht C, Mühlenhoff U.

Biochim Biophys Acta. 2012 Sep;1823(9):1491-508. doi: 10.1016/j.bbamcr.2012.05.009. Epub 2012 May 15. Review.

16.

A Mutation in Caenorhabditis elegans NDUF-7 Activates the Mitochondrial Stress Response and Prolongs Lifespan via ROS and CED-4.

Rauthan M, Ranji P, Abukar R, Pilon M.

G3 (Bethesda). 2015 Jun 1;5(8):1639-48. doi: 10.1534/g3.115.018598.

17.

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans.

Yang W, Hekimi S.

PLoS Biol. 2010 Dec 7;8(12):e1000556. doi: 10.1371/journal.pbio.1000556.

18.

Mitochondrial protein quality control during biogenesis and aging.

Baker BM, Haynes CM.

Trends Biochem Sci. 2011 May;36(5):254-61. doi: 10.1016/j.tibs.2011.01.004. Epub 2011 Feb 25. Review.

PMID:
21353780
19.

The mitochondrial unfolded protein response—synchronizing genomes.

Jovaisaite V, Auwerx J.

Curr Opin Cell Biol. 2015 Apr;33:74-81. doi: 10.1016/j.ceb.2014.12.003. Epub 2014 Dec 23. Review.

20.

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.

Lin YF, Schulz AM, Pellegrino MW, Lu Y, Shaham S, Haynes CM.

Nature. 2016 May 2;533(7603):416-9. doi: 10.1038/nature17989.

PMID:
27135930
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