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Items: 1 to 20 of 372

1.

Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

Gross O, Yazdi AS, Thomas CJ, Masin M, Heinz LX, Guarda G, Quadroni M, Drexler SK, Tschopp J.

Immunity. 2012 Mar 23;36(3):388-400. doi: 10.1016/j.immuni.2012.01.018.

2.

Regulation of interleukin 1α secretion by inflammasomes.

Yazdi AS, Drexler SK.

Ann Rheum Dis. 2013 Apr;72 Suppl 2:ii96-9. doi: 10.1136/annrheumdis-2012-202252. Epub 2012 Dec 19. Review.

PMID:
23253918
3.

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.

Pelegrin P, Barroso-Gutierrez C, Surprenant A.

J Immunol. 2008 Jun 1;180(11):7147-57.

4.

Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD.

Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG.

Eur Respir J. 2011 Nov;38(5):1019-28. doi: 10.1183/09031936.00158110. Epub 2011 May 26.

5.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

6.

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S.

PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6.

7.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

8.

Caspase-11: the driving factor for noncanonical inflammasomes.

Viganò E, Mortellaro A.

Eur J Immunol. 2013 Sep;43(9):2240-5. doi: 10.1002/eji.201343800. Review.

9.

Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β.

Angosto D, López-Castejón G, López-Muñoz A, Sepulcre MP, Arizcun M, Meseguer J, Mulero V.

Innate Immun. 2012 Dec;18(6):815-24. doi: 10.1177/1753425912441956. Epub 2012 Mar 28.

PMID:
22456941
10.

Non-canonical inflammasome activation targets caspase-11.

Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM.

Nature. 2011 Oct 16;479(7371):117-21. doi: 10.1038/nature10558.

PMID:
22002608
11.

Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.

Maier NK, Crown D, Liu J, Leppla SH, Moayeri M.

J Immunol. 2014 Jan 15;192(2):763-70. doi: 10.4049/jimmunol.1301434. Epub 2013 Dec 13.

12.

Inflammasomes in liver diseases.

Szabo G, Csak T.

J Hepatol. 2012 Sep;57(3):642-54. doi: 10.1016/j.jhep.2012.03.035. Epub 2012 May 23. Review.

13.

Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.

McCoy AJ, Koizumi Y, Higa N, Suzuki T.

J Immunol. 2010 Dec 1;185(11):7077-84. doi: 10.4049/jimmunol.1002165. Epub 2010 Oct 29.

14.

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.

Pétrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J.

Cell Death Differ. 2007 Sep;14(9):1583-9. Epub 2007 Jun 29.

15.

Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M.

J Immunol. 2010 Jul 15;185(2):1186-95. doi: 10.4049/jimmunol.1001058. Epub 2010 Jun 21.

17.

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo.

von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, Vance RE.

Nature. 2012 Oct 4;490(7418):107-11. doi: 10.1038/nature11351. Epub 2012 Aug 19.

18.

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE.

J Immunol. 2013 Nov 15;191(10):5239-46. doi: 10.4049/jimmunol.1301581. Epub 2013 Oct 11.

19.

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.

Bracey NA, Beck PL, Muruve DA, Hirota SA, Guo J, Jabagi H, Wright JR Jr, Macdonald JA, Lees-Miller JP, Roach D, Semeniuk LM, Duff HJ.

Exp Physiol. 2013 Feb;98(2):462-72. doi: 10.1113/expphysiol.2012.068338. Epub 2012 Jul 30.

20.

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.

Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F.

Nat Med. 2013 Jan;19(1):57-64. doi: 10.1038/nm.2999. Epub 2012 Dec 2.

PMID:
23202296
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