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Results: 1 to 20 of 93

1.

Tight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation.

Aryal RP, Ju T, Cummings RD.

J Biol Chem. 2012 May 4;287(19):15317-29. doi: 10.1074/jbc.M111.312587. Epub 2012 Mar 13.

PMID:
22416136
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase.

Aryal RP, Ju T, Cummings RD.

J Biol Chem. 2010 Jan 22;285(4):2456-62. doi: 10.1074/jbc.M109.065169. Epub 2009 Nov 18.

PMID:
19923218
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Identification of a novel protein binding motif within the T-synthase for the molecular chaperone Cosmc.

Aryal RP, Ju T, Cummings RD.

J Biol Chem. 2014 Apr 25;289(17):11630-41. doi: 10.1074/jbc.M114.555870. Epub 2014 Mar 10.

PMID:
24616093
[PubMed - indexed for MEDLINE]
4.

Co-translational function of Cosmc, core 1 synthase specific molecular chaperone, revealed by a cell-free translation system.

Narimatsu Y, Kubota T, Furukawa S, Shimojima M, Iwasaki H, Tozawa Y, Tachibana K, Narimatsu H.

FEBS Lett. 2011 May 6;585(9):1276-80. doi: 10.1016/j.febslet.2011.04.010. Epub 2011 Apr 9.

PMID:
21496458
[PubMed - indexed for MEDLINE]
Free Article
5.

Functional assays for the molecular chaperone cosmc.

Ju T, Cummings RD.

Methods Enzymol. 2010;479:107-22. doi: 10.1016/S0076-6879(10)79006-6.

PMID:
20816162
[PubMed - indexed for MEDLINE]
6.

The transmembrane domain of the molecular chaperone Cosmc directs its localization to the endoplasmic reticulum.

Sun Q, Ju T, Cummings RD.

J Biol Chem. 2011 Apr 1;286(13):11529-42. doi: 10.1074/jbc.M110.173591. Epub 2011 Jan 24.

PMID:
21262965
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc.

Ju T, Aryal RP, Stowell CJ, Cummings RD.

J Cell Biol. 2008 Aug 11;182(3):531-42. doi: 10.1083/jcb.200711151.

PMID:
18695044
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.

Ju T, Cummings RD.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16613-8. Epub 2002 Dec 3.

PMID:
12464682
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A novel fluorescent assay for T-synthase activity.

Ju T, Xia B, Aryal RP, Wang W, Wang Y, Ding X, Mi R, He M, Cummings RD.

Glycobiology. 2011 Mar;21(3):352-62. doi: 10.1093/glycob/cwq168. Epub 2010 Oct 19.

PMID:
20959392
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc.

Narimatsu Y, Ikehara Y, Iwasaki H, Nonomura C, Sato T, Nakanishi H, Narimatsu H.

Biochem Biophys Res Commun. 2008 Feb 1;366(1):199-205. Epub 2007 Dec 3.

PMID:
18061573
[PubMed - indexed for MEDLINE]
11.

Cosmc is an essential chaperone for correct protein O-glycosylation.

Wang Y, Ju T, Ding X, Xia B, Wang W, Xia L, He M, Cummings RD.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9228-33. doi: 10.1073/pnas.0914004107. Epub 2010 May 3.

PMID:
20439703
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans.

Ju T, Zheng Q, Cummings RD.

Glycobiology. 2006 Oct;16(10):947-58. Epub 2006 Jun 8.

PMID:
16762980
[PubMed - indexed for MEDLINE]
Free Article
13.

Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen.

Mi R, Song L, Wang Y, Ding X, Zeng J, Lehoux S, Aryal RP, Wang J, Crew VK, van Die I, Chapman AB, Cummings RD, Ju T.

J Biol Chem. 2012 Nov 30;287(49):41523-33. doi: 10.1074/jbc.M112.371989. Epub 2012 Oct 3. Erratum in: J Biol Chem. 2013 Apr 19;288(16):11505.

PMID:
23035125
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The residual pro-part of cathepsin C fulfills the criteria required for an intramolecular chaperone in folding and stabilizing the human proenzyme.

Cigić B, Dahl SW, Pain RH.

Biochemistry. 2000 Oct 10;39(40):12382-90.

PMID:
11015218
[PubMed - indexed for MEDLINE]
15.

Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6.

Chen J, Liu CC, Li Q, Nowak C, Bu G, Wang J.

Structure. 2011 Mar 9;19(3):313-23. doi: 10.1016/j.str.2011.01.010.

PMID:
21397183
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protein glycosylation: chaperone mutation in Tn syndrome.

Ju T, Cummings RD.

Nature. 2005 Oct 27;437(7063):1252.

PMID:
16251947
[PubMed - indexed for MEDLINE]
17.

The signal for Golgi retention of bovine beta 1,4-galactosyltransferase is in the transmembrane domain.

Teasdale RD, D'Agostaro G, Gleeson PA.

J Biol Chem. 1992 Feb 25;267(6):4084-96. Erratum in: J Biol Chem 1992 Jun 25;267(18):13113.

PMID:
1637374
[PubMed - indexed for MEDLINE]
Free Article
18.

Maturation of lipoprotein lipase in the endoplasmic reticulum. Concurrent formation of functional dimers and inactive aggregates.

Ben-Zeev O, Mao HZ, Doolittle MH.

J Biol Chem. 2002 Mar 22;277(12):10727-38. Epub 2002 Jan 16.

PMID:
11796709
[PubMed - indexed for MEDLINE]
Free Article
19.

An unstructured C-terminal region of the Hsp90 co-chaperone p23 is important for its chaperone function.

Weikl T, Abelmann K, Buchner J.

J Mol Biol. 1999 Oct 29;293(3):685-91.

PMID:
10543959
[PubMed - indexed for MEDLINE]
20.

Anti-chaperone behavior of BiP during the protein disulfide isomerase-catalyzed refolding of reduced denatured lysozyme.

Puig A, Gilbert HF.

J Biol Chem. 1994 Oct 14;269(41):25889-96.

PMID:
7929293
[PubMed - indexed for MEDLINE]
Free Article

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