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Results: 1 to 20 of 128

1.

Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains.

Houštek J, Hejzlarová K, Vrbacký M, Drahota Z, Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavy J, Mikšík I, Kazdová L, Oliyarnyk O, Kurtz T, Pravenec M.

Physiol Genomics. 2012 May 1;44(9):487-94. doi: 10.1152/physiolgenomics.00156.2011. Epub 2012 Mar 13.

PMID:
22414913
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction.

Houštěk J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Silhavý J, Simáková M, Mlejnek P, Kazdová L, Mikšík I, Neckář J, Papoušek F, Kolář F, Kurtz TW, Pravenec M.

Physiol Genomics. 2014 Sep 15;46(18):671-8. doi: 10.1152/physiolgenomics.00069.2014. Epub 2014 Jul 29.

PMID:
25073601
[PubMed - in process]
3.

Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains.

Pravenec M, Hyakukoku M, Houstek J, Zidek V, Landa V, Mlejnek P, Miksik I, Dudová-Mothejzikova K, Pecina P, Vrbacky M, Drahota Z, Vojtiskova A, Mracek T, Kazdova L, Oliyarnyk O, Wang J, Ho C, Qi N, Sugimoto K, Kurtz T.

Genome Res. 2007 Sep;17(9):1319-26. Epub 2007 Aug 10. Erratum in: Genome Res. 2008 Oct;18(10):1680.

PMID:
17693571
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Construction of two novel reciprocal conplastic rat strains and characterization of cardiac mitochondria.

Kumarasamy S, Gopalakrishnan K, Abdul-Majeed S, Partow-Navid R, Farms P, Joe B.

Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H22-32. doi: 10.1152/ajpheart.00534.2012. Epub 2012 Nov 2.

PMID:
23125210
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mitochondrial polymorphisms in rat genetic models of hypertension.

Kumarasamy S, Gopalakrishnan K, Shafton A, Nixon J, Thangavel J, Farms P, Joe B.

Mamm Genome. 2010 Jun;21(5-6):299-306. doi: 10.1007/s00335-010-9259-5. Epub 2010 May 5.

PMID:
20443117
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR.

Kren V, Qi N, Krenova D, Zidek V, Sladká M, Jáchymová M, Míková B, Horky K, Bonne A, Van Lith HA, Van Zutphen BF, Lau YF, Pravenec M, St Lezin E.

Hypertension. 2001 Apr;37(4):1147-52.

PMID:
11304517
[PubMed - indexed for MEDLINE]
Free Article
7.

Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension.

Pravenec M, Landa V, Zídek V, Musilová A, Kazdová L, Qi N, Wang J, St Lezin E, Kurtz TW.

Physiol Res. 2003;52(6):681-8.

PMID:
14640889
[PubMed - indexed for MEDLINE]
Free Article
8.

mt-Nd2 Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes.

Mathews CE, Leiter EH, Spirina O, Bykhovskaya Y, Gusdon AM, Ringquist S, Fischel-Ghodsian N.

Diabetologia. 2005 Feb;48(2):261-7. Epub 2005 Feb 4.

PMID:
15692809
[PubMed - indexed for MEDLINE]
9.

Voluntary running improves glucose tolerance and insulin resistance in female spontaneously hypertensive rats.

LaPier TL, Swislocki AL, Clark RJ, Rodnick KJ.

Am J Hypertens. 2001 Jul;14(7 Pt 1):708-15.

PMID:
11465658
[PubMed - indexed for MEDLINE]
10.

Reduced insulin receptor signaling in the obese spontaneously hypertensive Koletsky rat.

Friedman JE, Ishizuka T, Liu S, Farrell CJ, Bedol D, Koletsky RJ, Kaung HL, Ernsberger P.

Am J Physiol. 1997 Nov;273(5 Pt 1):E1014-23.

PMID:
9374689
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.

Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J.

Nat Genet. 1999 Jan;21(1):76-83.

PMID:
9916795
[PubMed - indexed for MEDLINE]
13.

Genetic analysis of metabolic defects in the spontaneously hypertensive rat.

Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz TW.

Mamm Genome. 2002 May;13(5):253-8.

PMID:
12016513
[PubMed - indexed for MEDLINE]
14.

Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat.

Pravenec M, Jansa P, Kostka V, Zídek V, Kren V, Forejt J, Kurtz TW.

Mamm Genome. 2001 Apr;12(4):295-8.

PMID:
11309661
[PubMed - indexed for MEDLINE]
15.

A new transgenic rat model of hepatic steatosis and the metabolic syndrome.

Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz TW.

Hypertension. 2005 May;45(5):1004-11. Epub 2005 Apr 4.

PMID:
15809359
[PubMed - indexed for MEDLINE]
Free Article
16.

Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat.

St Lezin E, Liu W, Wang N, Wang JM, Kren V, Zidek V, Zdobinska M, Krenova D, Bottger A, van Zutphen BF, Pravenec M.

Hypertension. 1998 Jan;31(1 Pt 2):373-7.

PMID:
9453331
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of FAT/CD36 in novel PKC isoform activation in heart of spontaneously hypertensive rats.

Klevstig MJ, Markova I, Burianova J, Kazdova L, Pravenec M, Novakova O, Novak F.

Mol Cell Biochem. 2011 Nov;357(1-2):163-9. doi: 10.1007/s11010-011-0886-2. Epub 2011 May 31.

PMID:
21625957
[PubMed - indexed for MEDLINE]
18.

Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.

Collison M, Glazier AM, Graham D, Morton JJ, Dominiczak MH, Aitman TJ, Connell JM, Gould GW, Dominiczak AF.

Diabetes. 2000 Dec;49(12):2222-6.

PMID:
11118030
[PubMed - indexed for MEDLINE]
19.

Effects of angiotensin II receptor antagonists on insulin resistance syndrome and leptin in sucrose-fed spontaneously hypertensive rats.

Umeda M, Kanda T, Murakami M.

Hypertens Res. 2003 Jun;26(6):485-92.

PMID:
12862206
[PubMed - indexed for MEDLINE]
Free Article
20.

Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension.

Pravenec M, Zidek V, Simakova M, Kren V, Krenova D, Horky K, Jachymova M, Mikova B, Kazdova L, Aitman TJ, Churchill PC, Webb RC, Hingarh NH, Yang Y, Wang JM, Lezin EM, Kurtz TW.

J Clin Invest. 1999 Jun;103(12):1651-7.

PMID:
10377171
[PubMed - indexed for MEDLINE]
Free PMC Article

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