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Items: 1 to 20 of 90

1.

A functional genetic screen reveals new regulators of β1-integrin activity.

Pellinen T, Rantala JK, Arjonen A, Mpindi JP, Kallioniemi O, Ivaska J.

J Cell Sci. 2012 Feb 1;125(Pt 3):649-61. doi: 10.1242/jcs.090704.

2.

Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer.

Virtakoivu R, Pellinen T, Rantala JK, Perälä M, Ivaska J.

Mol Biol Cell. 2012 Sep;23(17):3357-69. doi: 10.1091/mbc.E12-03-0213. Epub 2012 Jul 18.

3.

Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells.

Sameni M, Dosescu J, Yamada KM, Sloane BF, Cavallo-Medved D.

Mol Imaging. 2008 Sep-Oct;7(5):199-213.

4.

Matrix metalloproteinase-2 cleavage of the β1 integrin ectodomain facilitates colon cancer cell motility.

Kryczka J, Stasiak M, Dziki L, Mik M, Dziki A, Cierniewski C.

J Biol Chem. 2012 Oct 19;287(43):36556-66. doi: 10.1074/jbc.M112.384909. Epub 2012 Aug 16.

5.

Expression of estrogen receptor beta increases integrin alpha1 and integrin beta1 levels and enhances adhesion of breast cancer cells.

Lindberg K, Ström A, Lock JG, Gustafsson JA, Haldosén LA, Helguero LA.

J Cell Physiol. 2010 Jan;222(1):156-67. doi: 10.1002/jcp.21932.

PMID:
19780039
6.

Integrin β1 mediates epithelial growth factor-induced invasion in human ovarian cancer cells.

Lau MT, So WK, Leung PC.

Cancer Lett. 2012 Jul 28;320(2):198-204. doi: 10.1016/j.canlet.2012.02.028. Epub 2012 Mar 1.

PMID:
22388103
7.

miR-31 is a broad regulator of β1-integrin expression and function in cancer cells.

Augoff K, Das M, Bialkowska K, McCue B, Plow EF, Sossey-Alaoui K.

Mol Cancer Res. 2011 Nov;9(11):1500-8. doi: 10.1158/1541-7786.MCR-11-0311. Epub 2011 Aug 29.

8.

Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells.

Zhang Y, Gong Y, Hu D, Zhu P, Wang N, Zhang Q, Wang M, Aldeewan A, Xia H, Qu X, Ring BZ, Minato N, Su L.

Oncogene. 2015 Mar 12;34(11):1451-62. doi: 10.1038/onc.2014.36. Epub 2014 Apr 7.

PMID:
24704834
9.

β1 integrin is required for anchorage-independent growth and invasion of tumor cells in a context dependent manner.

Schooley AM, Andrews NM, Zhao H, Addison CL.

Cancer Lett. 2012 Mar 28;316(2):157-67. doi: 10.1016/j.canlet.2011.10.032. Epub 2011 Oct 30.

PMID:
22099877
10.

CD9 negatively regulates CD26 expression and inhibits CD26-mediated enhancement of invasive potential of malignant mesothelioma cells.

Okamoto T, Iwata S, Yamazaki H, Hatano R, Komiya E, Dang NH, Ohnuma K, Morimoto C.

PLoS One. 2014 Jan 23;9(1):e86671. doi: 10.1371/journal.pone.0086671. eCollection 2014.

11.

Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.

McSherry EA, Brennan K, Hudson L, Hill AD, Hopkins AM.

Breast Cancer Res. 2011 Mar 23;13(2):R31. doi: 10.1186/bcr2853.

12.

miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2).

Wang H, Zhu Y, Zhao M, Wu C, Zhang P, Tang L, Zhang H, Chen X, Yang Y, Liu G.

PLoS One. 2013 Aug 6;8(8):e70192. doi: 10.1371/journal.pone.0070192. Print 2013.

13.

Effects and mechanism of integrin-β1 gene expression inhibited by shRNA in invasion of pancreatic carcinoma PANC-1 cells.

Yu F, Li H, Bu X, Zhang Y.

Hepatogastroenterology. 2012 Mar-Apr;59(114):561-4. doi: 10.5754/hge10760.

PMID:
22353524
14.

Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.

Goel HL, Underwood JM, Nickerson JA, Hsieh CC, Languino LR.

J Cell Physiol. 2010 Jul;224(1):210-7. doi: 10.1002/jcp.22116.

15.

Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins.

Castelló-Cros R, Khan DR, Simons J, Valianou M, Cukierman E.

BMC Cancer. 2009 Mar 26;9:94. doi: 10.1186/1471-2407-9-94.

16.

The primacy of β1 integrin activation in the metastatic cascade.

Kato H, Liao Z, Mitsios JV, Wang HY, Deryugina EI, Varner JA, Quigley JP, Shattil SJ.

PLoS One. 2012;7(10):e46576. doi: 10.1371/journal.pone.0046576. Epub 2012 Oct 3.

17.
18.

Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma.

Perlino E, Lovecchio M, Vacca RA, Fornaro M, Moro L, Ditonno P, Battaglia M, Selvaggi FP, Mastropasqua MG, Bufo P, Languino LR.

Am J Pathol. 2000 Nov;157(5):1727-34.

19.
20.

Adhesion and protease activity in cell lines from human salivary gland tumors are regulated by the laminin-derived peptide AG73, syndecan-1 and beta1 integrin.

Gama-de-Souza LN, Cyreno-Oliveira E, Freitas VM, Melo ES, Vilas-Boas VF, Moriscot AS, Jaeger RG.

Matrix Biol. 2008 Jun;27(5):402-19. doi: 10.1016/j.matbio.2008.02.007. Epub 2008 Feb 29.

PMID:
18378436
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