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Items: 1 to 20 of 90

1.

Hepatoprotectant ursodeoxycholyl lysophosphatidylethanolamide increasing phosphatidylcholine levels as a potential therapy of acute liver injury.

Chamulitrat W, Zhang W, Xu W, Pathil A, Setchell K, Stremmel W.

Front Physiol. 2012 Feb 20;3:24. doi: 10.3389/fphys.2012.00024. eCollection 2012.

2.

The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury.

Pathil A, Warth A, Chamulitrat W, Stremmel W.

J Hepatol. 2011 Apr;54(4):674-84. doi: 10.1016/j.jhep.2010.07.028. Epub 2010 Sep 27.

PMID:
21146893
3.

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent.

Chamulitrat W, Burhenne J, Rehlen T, Pathil A, Stremmel W.

Hepatology. 2009 Jul;50(1):143-54. doi: 10.1002/hep.22955.

PMID:
19496180
4.

Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD.

Pathil A, Liebisch G, Okun JG, Chamulitrat W, Schmitz G, Stremmel W.

Eur J Clin Invest. 2015 Sep;45(9):925-31. doi: 10.1111/eci.12486. Epub 2015 Jul 14.

PMID:
26108973
5.

Ursodeoxycholyl lysophosphatidylethanolamide protects against hepatic ischemia and reperfusion injury in mice.

Wang J, Deng X, Yi S, Pathil A, Zhang W, Setchell K, Stremmel W, Chamulitrat W.

Shock. 2015 Apr;43(4):379-86. doi: 10.1097/SHK.0000000000000312.

PMID:
25526375
6.

Ursodeoxycholyl lysophosphatidylethanolamide inhibits lipoapoptosis by shifting fatty acid pools toward monosaturated and polyunsaturated fatty acids in mouse hepatocytes.

Chamulitrat W, Liebisch G, Xu W, Gan-Schreier H, Pathil A, Schmitz G, Stremmel W.

Mol Pharmacol. 2013 Nov;84(5):696-709. doi: 10.1124/mol.113.088039. Epub 2013 Aug 23.

7.

Comparison of different bile acid-phospholipid conjugates in acute hepatitis.

Pathil A, Warth A, Chamulitrat W, Stremmel W.

Eur J Clin Invest. 2012 Feb;42(2):130-8. doi: 10.1111/j.1365-2362.2011.02563.x. Epub 2011 Jun 27.

PMID:
21707612
8.

Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease.

Pathil A, Mueller J, Warth A, Chamulitrat W, Stremmel W.

Hepatology. 2012 May;55(5):1369-78. doi: 10.1002/hep.25531. Epub 2012 Mar 18.

PMID:
22183915
9.

Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins.

Sellinger M, Xu W, Pathil A, Stremmel W, Chamulitrat W.

Exp Biol Med (Maywood). 2015 Feb;240(2):252-60. doi: 10.1177/1535370214547157. Epub 2014 Aug 14.

PMID:
25125499
10.

Effect of ursodeoxycholic acid on in vivo and in vitro toxic liver injury in rats.

Simko V, Michael S.

Aliment Pharmacol Ther. 1994 Jun;8(3):315-22.

PMID:
7918927
11.
13.

[Protective effect of heme oxygenase-1 and its reaction product, carbon monoxide on acute liver injury induced by carbon tetrachloride in rats].

Wen T, Zhao JY, Mei S, Guan L, Zhang YL.

Beijing Da Xue Xue Bao. 2006 Dec 18;38(6):618-22. Chinese.

14.

Effect of S-adenosyl-L-methionine and dilinoleoylphosphatidylcholine on liver lipid composition and ethanol hepatotoxicity in isolated perfused rat liver.

Gigliozzi A, Romeo R, Fraioli F, Cantafora A, Delle Monache M, Cardilli A, Attili AF, Scafato E, Carli L, Alvaro D.

Dig Dis Sci. 1998 Oct;43(10):2211-22.

PMID:
9790456
15.

Studies on the mechanism of the ursodeoxycholic acid-induced increase in hepatic low-density lipoprotein binding.

Bouscarel B, Ceryak S, Robins SJ, Fromm H.

Lipids. 1995 Jul;30(7):607-17.

PMID:
7564915
16.

Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.

Rolo AP, Palmeira CM, Wallace KB.

Toxicol Lett. 2002 Feb 7;126(3):197-203.

PMID:
11814708
17.

Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice.

Fiorucci S, Antonelli E, Distrutti E, Mencarelli A, Farneti S, Del Soldato P, Morelli A.

Br J Pharmacol. 2004 Sep;143(1):33-42. Retraction in: Br J Pharmacol. 2009 Mar;156(5):868.

18.

Effect of cholestyramine on bile acid pattern and synthesis during administration of ursodeoxycholic acid in man.

Rust C, Sauter GH, Oswald M, Büttner J, Kullak-Ublick GA, Paumgartner G, Beuers U.

Eur J Clin Invest. 2000 Feb;30(2):135-9.

PMID:
10651838
19.

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation.

Rodrigues CM, Fan G, Ma X, Kren BT, Steer CJ.

J Clin Invest. 1998 Jun 15;101(12):2790-9.

20.

Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants.

Mitsuyoshi H, Nakashima T, Sumida Y, Yoh T, Nakajima Y, Ishikawa H, Inaba K, Sakamoto Y, Okanoue T, Kashima K.

Biochem Biophys Res Commun. 1999 Sep 24;263(2):537-42.

PMID:
10491327
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